{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T21:04:39Z","timestamp":1787951079729,"version":"build-2784847793"},"reference-count":72,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T00:00:00Z","timestamp":1726704000000},"content-version":"vor","delay-in-days":262,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["NNP project (BT\/PR40265\/BTIS\/137\/62\/2023)"],"award-info":[{"award-number":["NNP project (BT\/PR40265\/BTIS\/137\/62\/2023)"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["NNP project (BT\/PR40265\/BTIS\/137\/62\/2023)"],"award-info":[{"award-number":["NNP project (BT\/PR40265\/BTIS\/137\/62\/2023)"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Autophagy pathway plays a central role in cellular degradation. The proteins involved in the core autophagy process are mostly localised on membranes or interact indirectly with lipid-associated proteins. Therefore, progress in structure determination of \u2018core autophagy proteins\u2019 remained relatively limited. Recent paradigm shift in structural biology that includes cutting-edge cryo-EM technology and robust AI-based Alphafold2 predicted models has significantly increased data points in biology. Here, we developed Autophagy3D, a web-based resource that provides an efficient way to access data associated with 40 core human autophagic proteins (80322 structures), their protein-protein interactors and ortholog structures from various species. Autophagy3D also offers detailed visualizations of protein structures, and, hence deriving direct biological insights. The database significantly enhances access to information as full datasets are available for download. The Autophagy3D can be publicly accessed via https:\/\/autophagy3d.igib.res.in.<\/jats:p>\n               <jats:p>Database URL: https:\/\/autophagy3d.igib.res.in<\/jats:p>","DOI":"10.1093\/database\/baae088","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T16:37:58Z","timestamp":1726763878000},"source":"Crossref","is-referenced-by-count":2,"title":["Autophagy3D: a comprehensive autophagy structure database"],"prefix":"10.1093","volume":"2024","author":[{"family":"Neha","sequence":"first","affiliation":[{"name":"Computational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology , Mathura Road, New Delhi 110025, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesu","family":"Castin","sequence":"additional","affiliation":[{"name":"Computational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology , Mathura Road, New Delhi 110025, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saman","family":"Fatihi","sequence":"additional","affiliation":[{"name":"Computational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology , Mathura Road, New Delhi 110025, India"},{"name":"Academy of Scientific and Innovative Research (AcSIR) , Ghaziabad 201002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepanshi","family":"Gahlot","sequence":"additional","affiliation":[{"name":"Computational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology , Mathura Road, New Delhi 110025, India"},{"name":"Academy of Scientific and Innovative Research (AcSIR) , Ghaziabad 201002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akanksha","family":"Arun","sequence":"additional","affiliation":[{"name":"Computational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology , Mathura Road, New Delhi 110025, India"},{"name":"Academy of Scientific and Innovative Research (AcSIR) , Ghaziabad 201002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1961-039X","authenticated-orcid":false,"given":"Lipi","family":"Thukral","sequence":"additional","affiliation":[{"name":"Computational Structural Biology Lab, CSIR-Institute of Genomics and Integrative Biology , Mathura Road, New Delhi 110025, India"},{"name":"Academy of Scientific and Innovative Research (AcSIR) , Ghaziabad 201002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,9,19]]},"reference":[{"key":"2024091916171161000_R1","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.1038\/ncb1991","article-title":"A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation","volume":"11","author":"Hayashi-Nishino","year":"2009","journal-title":"Nat Cell 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