{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T11:53:47Z","timestamp":1773662027209,"version":"3.50.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2016,10,3]],"date-time":"2016-10-03T00:00:00Z","timestamp":1475452800000},"content-version":"vor","delay-in-days":1371,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,1,1]]},"DOI":"10.1093\/database\/bat059","type":"journal-article","created":{"date-parts":[[2013,8,11]],"date-time":"2013-08-11T00:13:59Z","timestamp":1376180039000},"source":"Crossref","is-referenced-by-count":83,"title":["Version 6 of the consensus yeast metabolic network refines biochemical coverage and improves model performance"],"prefix":"10.1093","volume":"2013","author":[{"given":"Benjamin D.","family":"Heavner","sequence":"first","affiliation":[{"name":"Institute for Systems Biology, 401 Terry Ave N., Seattle, WA 98109, USA, 2Manchester Centre for Integrative Systems Biology, University of Manchester, Manchester, M1 7DN, UK and 3Biomass Conversion Laboratory, Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, USA"}]},{"given":"Kieran","family":"Smallbone","sequence":"additional","affiliation":[{"name":"Institute for Systems Biology, 401 Terry Ave N., Seattle, WA 98109, USA, 2Manchester Centre for Integrative Systems Biology, University of Manchester, Manchester, M1 7DN, UK and 3Biomass Conversion Laboratory, Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, USA"}]},{"given":"Nathan D.","family":"Price","sequence":"additional","affiliation":[{"name":"Institute for Systems Biology, 401 Terry Ave N., Seattle, WA 98109, USA, 2Manchester Centre for Integrative Systems Biology, University of Manchester, Manchester, M1 7DN, UK and 3Biomass Conversion Laboratory, Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, USA"}]},{"given":"Larry P.","family":"Walker","sequence":"additional","affiliation":[{"name":"Institute for Systems Biology, 401 Terry Ave N., Seattle, WA 98109, USA, 2Manchester Centre for Integrative Systems Biology, University of Manchester, Manchester, M1 7DN, UK and 3Biomass Conversion Laboratory, Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, USA"}]}],"member":"286","published-online":{"date-parts":[[2013,8,9]]},"reference":[{"key":"key\n\t\t\t\t20180618202229_bat059-B1","first-page":"37","article-title":"Connecting extracellular metabolomic measurements to intracellular flux states in yeast","volume":"3","author":"Mo","year":"2009","journal-title":"BMC Syst. Biol."},{"key":"key\n\t\t\t\t20180618202229_bat059-B2","first-page":"1421","article-title":"Metabolic functions of duplicate genes in Saccharomyces cerevisiae","volume":"15","author":"Kuepfer","year":"2005","journal-title":"Genome Res."},{"key":"key\n\t\t\t\t20180618202229_bat059-B3","first-page":"1155","article-title":"A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology","volume":"26","author":"Herrgard","year":"2008","journal-title":"Nat. Biotech."},{"key":"key\n\t\t\t\t20180618202229_bat059-B4","first-page":"145","article-title":"Further developments towards a genome-scale metabolic model of yeast","volume":"4","author":"Dobson","year":"2010","journal-title":"BMC Syst. Biol."},{"key":"key\n\t\t\t\t20180618202229_bat059-B5","first-page":"55","article-title":"Yeast 5 - an expanded reconstruction of the Saccharomyces cerevisiae metabolic network","volume":"6","author":"Heavner","year":"2012","journal-title":"BMC Syst. Biol."},{"key":"key\n\t\t\t\t20180618202229_bat059-B6","first-page":"1290","article-title":"Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0","volume":"6","author":"Schellenberger","year":"2011","journal-title":"Nat. Protoc."},{"key":"key\n\t\t\t\t20180618202229_bat059-B7","first-page":"886","article-title":"Genome-scale models of microbial cells: evaluating the consequences of constraints","volume":"2","author":"Price","year":"2004","journal-title":"Nat. Rev. Microbiol."},{"key":"key\n\t\t\t\t20180618202229_bat059-B8","first-page":"178","article-title":"Improving the iMM 904 S. cerevisiae metabolic model using essentiality and synthetic lethality data","volume":"4","author":"Zomorrodi","year":"2010","journal-title":"BMC Syst. Biol."},{"key":"key\n\t\t\t\t20180618202229_bat059-B9","first-page":"271","article-title":"Anaerobic nutrition of Saccharomyces cerevisiae. II. Unsaturated fatty acid requirement for growth in a defined medium","volume":"43","author":"Andreasen","year":"1954","journal-title":"J. Cell. Physiol."},{"key":"key\n\t\t\t\t20180618202229_bat059-B10","first-page":"23","article-title":"Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for growth in a defined medium","volume":"41","author":"Andreasen","year":"1953","journal-title":"J. Cell. Physiol."},{"key":"key\n\t\t\t\t20180618202229_bat059-B11","first-page":"524","article-title":"The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models","volume":"19","author":"Hucka","year":"2003","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t20180618202229_bat059-B12","first-page":"1509","article-title":"Minimum information requested in the annotation of biochemical models (MIRIAM)","volume":"23","author":"Nov\u00e8re","year":"2005","journal-title":"Nat. Biotechnol."},{"key":"key\n\t\t\t\t20180618202229_bat059-B13","first-page":"D43","article-title":"Update on activities at the Universal Protein Resource (UniProt) in 2013","volume":"41","author":"The UniProt Consortium","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20180618202229_bat059-B14","first-page":"D456","article-title":"The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013","volume":"41","author":"Hastings","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20180618202229_bat059-B15","first-page":"901","article-title":"Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis","volume":"285","author":"Winzeler","year":"1999","journal-title":"Science"},{"key":"key\n\t\t\t\t20180618202229_bat059-B16","first-page":"460","article-title":"The use of \u201coverall accuracy\u201d to evaluate the validity of screening or diagnostic tests","volume":"19","author":"Alberg","year":"2004","journal-title":"J. Gen. Intern. Med."},{"key":"key\n\t\t\t\t20180618202229_bat059-B17","first-page":"195","article-title":"Machine learning for the detection of oil spills in satellite radar images","volume":"30","author":"Kubat","year":"1998","journal-title":"Mach. Learn."},{"key":"key\n\t\t\t\t20180618202229_bat059-B18","first-page":"412","article-title":"Assessing the accuracy of prediction algorithms for classification: an overview","volume":"16","author":"Baldi","year":"2000","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t20180618202229_bat059-B19","first-page":"D700","article-title":"Saccharomyces Genome Database: the genomics resource of budding yeast","volume":"40","author":"Cherry","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20180618202229_bat059-B20","first-page":"1","article-title":"Gap detection for genome-scale constraint-based models","volume":"2012","author":"Brooks","year":"2012","journal-title":"Adv. Bioinformatics"},{"key":"key\n\t\t\t\t20180618202229_bat059-B21","first-page":"299","article-title":"Integration of expression data in genome-scale metabolic network reconstructions","volume":"3","author":"Blazier","year":"2012","journal-title":"Front. Physiol."},{"key":"key\n\t\t\t\t20180618202229_bat059-B22","first-page":"17845","article-title":"Probabilistic integrative modeling of genome-scale metabolic and regulatory networks in Escherichia coli and Mycobacterium tuberculosis","volume":"107","author":"Chandrasekaran","year":"2010","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"key\n\t\t\t\t20180618202229_bat059-B23","first-page":"e27316","article-title":"Genome-Scale consequences of cofactor balancing in engineered pentose utilization pathways in Saccharomyces cerevisiae","volume":"6","author":"Ghosh","year":"2011","journal-title":"PLoS One"}],"container-title":["Database"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/database\/article-pdf\/doi\/10.1093\/database\/bat059\/16733959\/bat059.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,6,19]],"date-time":"2018-06-19T00:35:29Z","timestamp":1529368529000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/database\/article\/doi\/10.1093\/database\/bat059\/339930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,1]]},"references-count":23,"URL":"https:\/\/doi.org\/10.1093\/database\/bat059","relation":{},"ISSN":["1758-0463"],"issn-type":[{"value":"1758-0463","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2013]]},"published":{"date-parts":[[2013,1,1]]}}}