{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T03:11:16Z","timestamp":1780110676258,"version":"3.54.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["EMBO Rep"],"published-print":{"date-parts":[[2001,2,1]]},"DOI":"10.1093\/embo-reports\/kve022","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T18:48:15Z","timestamp":1027709295000},"page":"113-118","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":576,"title":["The histone H4 acetyltransferase MOF uses a C2HC zinc finger for substrate recognition"],"prefix":"10.1038","volume":"2","author":[{"given":"Asifa","family":"Akhtar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2001,2,1]]},"reference":[{"key":"BFEMBR486_CR1","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S1097-2765(00)80431-1","volume":"5","author":"A. Akhtar","year":"2000","unstructured":"Akhtar, A. and Becker, P.B. (2000) Activation of transcription through histone H4 acetylation by MOF, an acetyl transferase essential for dosage compensation in Drosophila. Mol. Cell, 5, 367\u2013375.","journal-title":"Mol. Cell"},{"key":"BFEMBR486_CR2","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/35030169","volume":"407","author":"A. Akhtar","year":"2000","unstructured":"Akhtar, A., Zink, D. and Becker, P.B. (2000) Chromodomains as RNA interaction modules. Nature, 407, 405\u2013409.","journal-title":"Nature"},{"key":"BFEMBR486_CR3","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1093\/genetics\/153.4.1825","volume":"153","author":"G. Arrizabalaga","year":"1999","unstructured":"Arrizabalaga, G. and Lehmann, R. (1999) A selective screen reveals discrete functional domains in Drosophila Nanos. Genetics, 153, 1825\u20131838.","journal-title":"Genetics"},{"key":"BFEMBR486_CR4","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1146\/annurev.ge.28.120194.002423","volume":"28","author":"B.S. Baker","year":"1994","unstructured":"Baker, B.S., Gorman, M. and Marin, I. (1994) Dosage compensation in Drosophila. Annu. Rev. Genet., 28, 491\u2013521.","journal-title":"Annu. Rev. Genet."},{"key":"BFEMBR486_CR5","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0968-0004(99)01516-9","volume":"25","author":"C.E. Brown","year":"2000","unstructured":"Brown, C.E., Lechner, T., Howe, L. and Workman, J.L. (2000). The many HATs of transcription coactivators. Trends Biochem. Sci., 25, 15\u201319.","journal-title":"Trends Biochem. Sci."},{"key":"BFEMBR486_CR6","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/emboj\/16.3.555","volume":"16","author":"R. Candau","year":"1997","unstructured":"Candau, R., Zhou, J.X., Allis, C.D. and Berger, S.L. (1997). Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo. EMBO J. 16, 555\u2013565","journal-title":"EMBO J."},{"key":"BFEMBR486_CR7","doi-asserted-by":"crossref","unstructured":"Clapier, C., L\u00e4ngst, G., Corona, D.F.V., Becker, P.B. and Nightingale, K.P. (2001). A key role for the histone H4 N\u2010terminus in nucleosome remodeling by ISWI. Mol. Cell. Biol., in press.","DOI":"10.1128\/MCB.21.3.875-883.2001"},{"key":"BFEMBR486_CR8","doi-asserted-by":"crossref","first-page":"4557","DOI":"10.1093\/nar\/23.22.4557","volume":"23","author":"J.S. Godde","year":"1995","unstructured":"Godde, J.S., Nakatani, Y. and Wolffe, A.P. (1995). The amino\u2010terminal tails of the core histones and the translational position of the TATA box determine TBP\/TFIIA association with nucleosomal DNA. Nucleic Acids Res., 23, 4557\u20134564.","journal-title":"Nucleic Acids Res."},{"key":"BFEMBR486_CR9","doi-asserted-by":"crossref","first-page":"8185","DOI":"10.1128\/JVI.73.10.8185-8195.1999","volume":"73","author":"R.J. Gorelick","year":"1999","unstructured":"Gorelick, R.J., Fu, W., Gagliardi, T.D., Bosche, W.J., Rein, A., Henderson, L.E. and Arthur, L.O. (1999) Characterization of the block in replication of nucleocapsid protein zinc finger mutants from moloney murine leukemia virus. J. Virol., 73, 8185\u20138195.","journal-title":"J. Virol."},{"key":"BFEMBR486_CR10","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1006\/scdb.1999.0298","volume":"10","author":"P.A. Grant","year":"1999","unstructured":"Grant, P.A. and Berger, S.L. (1999) Histone acetyltransferase complexes. Semin. Cell Dev. Biol., 10, 169\u2013177.","journal-title":"Semin. Cell Dev. Biol."},{"key":"BFEMBR486_CR11","first-page":"1","volume":"19","author":"W. Gu","year":"2000","unstructured":"Gu, W., Wei, X., Pannuti, A. and Lucchesi, J.C. (2000) Targeting the chromatin\u2010remodeling MSL complex of Drosophila to its sites of action on the X chromosome requires both acetyl transferase and ATPase activities. EMBO J., 19, 1\u201310.","journal-title":"EMBO J."},{"key":"BFEMBR486_CR12","doi-asserted-by":"crossref","first-page":"12723","DOI":"10.1021\/bi961149j","volume":"35","author":"A. Hammarstrom","year":"1996","unstructured":"Hammarstrom, A., Berndt, K.D., Sillard, R., Adermann, K. and Otting, G. (1996) Solution structure of a naturally\u2010occurring zinc\u2010peptide complex demonstrates that the N\u2010terminal zinc\u2010binding module of the Lasp\u20101 LIM domain is an independent folding unit. Biochemistry, 35, 12723\u201312732.","journal-title":"Biochemistry"},{"key":"BFEMBR486_CR13","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1093\/emboj\/16.8.2054","volume":"16","author":"A. Hilfiker","year":"1997","unstructured":"Hilfiker, A., Hilfiker\u2010Kleiner, D., Pannuti, A. and Lucchesi, J.C. (1997) mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila. EMBO J., 16, 2054\u20132060.","journal-title":"EMBO J."},{"key":"BFEMBR486_CR14","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/566","volume":"19","author":"A.V. Ivanova","year":"1998","unstructured":"Ivanova, A.V., Bonaduce, M.J., Ivanov, S.V. and Klar, A.J. (1998) The chromo and SET domains of the Clr4 protein are essential for silencing in fission yeast. Nature Genet., 19, 192\u2013195.","journal-title":"Nature Genet."},{"key":"BFEMBR486_CR15","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0959-437X(98)80139-1","volume":"8","author":"J.C. Lucchesi","year":"1998","unstructured":"Lucchesi, J.C. (1998) Dosage compensation in flies and worms: the ups and downs of X\u2010chromosome regulation. Curr. Opin. Genet. Dev., 8, 179\u2013184.","journal-title":"Curr. Opin. Genet. Dev."},{"key":"BFEMBR486_CR16","doi-asserted-by":"crossref","first-page":"R807","DOI":"10.1016\/S0960-9822(99)80495-3","volume":"9","author":"J.C. Lucchesi","year":"1999","unstructured":"Lucchesi, J.C. (1999) Dosage compensation: roX marks the spot. Curr. Biol., 9, R807\u2013R808.","journal-title":"Curr. Biol."},{"key":"BFEMBR486_CR17","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1006\/jmbi.1997.1235","volume":"272","author":"K. Luger","year":"1997","unstructured":"Luger, K., Rechsteiner, T.J., Flaus, A.J., Waye, M.M. and Richmond, T.J. (1997) Characterization of nucleosome core particles containing histone proteins made in bacteria. J. Mol. Biol., 272, 301\u2013311.","journal-title":"J. Mol. Biol."},{"key":"BFEMBR486_CR18","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S0960-9822(00)00311-0","volume":"10","author":"V.H. Meller","year":"2000","unstructured":"Meller, V.H., Gordadze, P.R., Park, Y., Chu, X., Stuckenholz, C., Kelley, R.L. and Kuroda, M.I. (2000) Ordered assembly of roX RNAs into MSL complexes on the dosage\u2010compensated X chromosome in Drosophila. Curr. Biol., 10, 136\u2013143.","journal-title":"Curr. Biol."},{"key":"BFEMBR486_CR19","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1073\/pnas.88.1.263","volume":"88","author":"R. Paro","year":"1991","unstructured":"Paro, R. and Hogness, D.S. (1991) The Polycomb protein shares a homologous domain with a heterochromatin\u2010associated protein of Drosophila. Proc. Natl Acad. Sci. USA, 88, 263\u2013267.","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFEMBR486_CR20","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.1073\/pnas.93.7.2822","volume":"93","author":"P.V. Pedone","year":"1996","unstructured":"Pedone, P.V., Ghirlando, R., Clore, G.M., Gronenborn, A.M., Felsenfeld, G. and Omichinski, J.G. (1996) The single Cys2\u2010His2 zinc finger domain of the GAGA protein flanked by basic residues is sufficient for high\u2010affinity specific DNA binding Proc. Natl Acad. Sci. USA, 93, 2822\u20132826.","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"BFEMBR486_CR21","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1091\/mbc.8.2.219","volume":"8","author":"K.L. Schmeichel","year":"1997","unstructured":"Schmeichel, K.L. and Beckerle, M.C. (1997) Molecular dissection of a LIM domain. Mol. Biol. Cell, 8, 219\u2013230.","journal-title":"Mol. Biol. Cell"},{"key":"BFEMBR486_CR22","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/nsb0694-345","volume":"1","author":"J.W. Schwabe","year":"1994","unstructured":"Schwabe, J.W. and Klug, A. (1994) Zinc mining for protein domains. Nature Struct. Biol., 1, 345\u2013349.","journal-title":"Nature Struct. Biol."},{"key":"BFEMBR486_CR23","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1128\/MCB.20.1.312-318.2000","volume":"20","author":"E.R. Smith","year":"2000","unstructured":"Smith, E.R., Pannuti, A., Gu, W., Steurnagel, A., Cook, R.G., Allis, C.D. and Lucchesi, J.C. (2000) The Drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation. Mol. Cell. Biol., 20, 312\u2013318.","journal-title":"Mol. Cell. Biol."},{"key":"BFEMBR486_CR24","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/47412","volume":"403","author":"B.D. Strahl","year":"2000","unstructured":"Strahl, B.D. and Allis, C.D. (2000) The language of covalent histone modifications. Nature, 403, 41\u201345.","journal-title":"Nature"},{"key":"BFEMBR486_CR25","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/S0168-9525(99)01855-7","volume":"15","author":"C. Stuckenholz","year":"1999","unstructured":"Stuckenholz, C., Kageyama, Y. and Kuroda, M.I. (1999) Guilt by association: non\u2010coding RNAs, chromosome\u2010specific proteins and dosage compensation in Drosophila. Trends Genet., 15, 454\u2013458.","journal-title":"Trends Genet."},{"key":"BFEMBR486_CR26","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1006\/bbrc.1999.1836","volume":"266","author":"S. Takechi","year":"1999","unstructured":"Takechi, S. and Nakayama, T. (1999) Sas3 is a histone acetyltransferase and requires a zinc finger motif. Biochem. Biophys. Res. Commun., 266, 405\u2013410.","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"BFEMBR486_CR27","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1006\/jmbi.1998.2521","volume":"287","author":"M.A. Urbaneja","year":"1999","unstructured":"Urbaneja, M.A., Kane, B.P., Johnson, D.G., Gorelick, R.J., Henderson, L.E. and Casas\u2010Finet, J.R. (1999) Binding properties of the human immunodeficiency virus type 1 nucleocapsid protein p7 to a model RNA: elucidation of the structural determinants for function. J. Mol. Biol., 287, 59\u201375.","journal-title":"J. Mol. Biol."}],"container-title":["The EMBO Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1093%2Fembo-reports%2Fkve022","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1093\/embo-reports\/kve022.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1093\/embo-reports\/kve022","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1093\/embo-reports\/kve022\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.embopress.org\/doi\/pdf\/10.1093\/embo-reports\/kve022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1093\/embo-reports\/kve022.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T12:28:27Z","timestamp":1779107307000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1093\/embo-reports\/kve022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,2,1]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,2,1]]}},"alternative-id":["BFEMBR486"],"URL":"https:\/\/doi.org\/10.1093\/embo-reports\/kve022","relation":{},"ISSN":["1469-221X","1469-3178"],"issn-type":[{"value":"1469-221X","type":"print"},{"value":"1469-3178","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,2,1]]},"assertion":[{"value":"11 October 2000","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2000","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2000","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 February 2001","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}