{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T17:23:39Z","timestamp":1780593819832,"version":"3.54.1"},"reference-count":88,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T00:00:00Z","timestamp":1728950400000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32125033"],"award-info":[{"award-number":["32125033"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Historically, there have been many outbreaks of viral diseases that have continued to claim millions of lives. Research on human\u2013virus protein\u2013protein interactions (PPIs) is vital to understanding the principles of human\u2013virus relationships, providing an essential foundation for developing virus control strategies to combat diseases. The rapidly accumulating data on human\u2013virus PPIs offer unprecedented opportunities for bioinformatics research around human\u2013virus PPIs. However, available detailed analyses and summaries to help use these resources systematically and efficiently are lacking. Here, we comprehensively review the bioinformatic resources used in human\u2013virus PPI research, and discuss and compare their functions, performance, and limitations. This review aims to provide researchers with a bioinformatic toolbox that will hopefully better facilitate the exploration of human\u2013virus PPIs based on binding modes.<\/jats:p>","DOI":"10.1093\/gpbjnl\/qzae075","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T16:40:04Z","timestamp":1729010404000},"source":"Crossref","is-referenced-by-count":3,"title":["Bioinformatic Resources for Exploring Human\u2013virus Protein\u2013protein Interactions Based on Binding Modes"],"prefix":"10.1093","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-8816-2579","authenticated-orcid":false,"given":"Huimin","family":"Chen","sequence":"first","affiliation":[{"name":"State Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensor Technology and Health, Central China Normal University , Wuhan 430079,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2527-6502","authenticated-orcid":false,"given":"Jiaxin","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensor Technology and Health, Central China Normal University , Wuhan 430079,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8718-7677","authenticated-orcid":false,"given":"Gege","family":"Tang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensor Technology and Health, Central China Normal University , Wuhan 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