{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T09:22:15Z","timestamp":1789118535980,"version":"build-2803163510"},"reference-count":63,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T00:00:00Z","timestamp":1764633600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Although extensive evidence has underscored the critical role of alternative splicing (AS) in generating mature circular RNA (circRNA) isoforms and augmenting their functional diversity, a significant gap remains in the availability of specialized databases housing circRNA AS events. To bridge this gap, we develop circASbase, a pioneering and comprehensive database that catalogs 452,129 AS events in 884,047 full-length circRNAs from 581 samples across 13 species, and provides rich annotations to facilitate understanding the splicing regulation of circRNA. Our findings reveal substantial differences between circRNAs and linear transcripts regarding the distribution and occurrence of AS events, highlighting the unique regulatory landscape of circRNAs. These special splicing events result in functional differences of circRNAs by affecting internal ribosome entry sites, N6-methyladenosine sites, open reading frames, protein features, microRNA targets, and more. In summary, circASbase not only meets the urgent need of the research community for data repositories, but also represents a significant advancement in our understanding of circRNA biology. With its user-friendly interfaces and web-based visualization tools, circASbase is poised to become an indispensable resource for researchers exploring the regulatory mechanisms and functional roles of AS events in circRNAs. This database will continuously drive new insights and discoveries in the field, setting the stage for further advancements in circRNA research. circASbase is freely available at http:\/\/reprod.njmu.edu.cn\/cgi-bin\/circASbase\/.<\/jats:p>","DOI":"10.1093\/gpbjnl\/qzaf121","type":"journal-article","created":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T16:22:32Z","timestamp":1764692552000},"source":"Crossref","is-referenced-by-count":1,"title":["circASbase: A Comprehensive Database of Alternative Splicing Events in circRNAs"],"prefix":"10.1093","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7158-4750","authenticated-orcid":false,"given":"Lingxiao","family":"Zou (\u90b9\u51cc\u9704)","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics , Nanjing 211106,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7857-4766","authenticated-orcid":false,"given":"Jian","family":"Zhao (\u8d75\u5065)","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics , Nanjing 211106,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0858-9130","authenticated-orcid":false,"given":"Haojie","family":"Li (\u674e\u8c6a\u6770)","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Reproductive Medicine and Offspring Health, Department of Histology and Embryology, Nanjing Medical University , Nanjing 211166,","place":["China"]},{"name":"Changzhou Medical Center, The Affiliated Changzhou Second People\u2019s Hospital of Nanjing Medical University, Changzhou Second People\u2019s Hospital, Nanjing Medical University , Changzhou 213000,","place":["China"]},{"name":"Medical Research Center, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University , Changzhou 213000,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9641-0685","authenticated-orcid":false,"given":"Chen","family":"Xu (\u8bb8\u741b)","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Reproductive Medicine and Offspring Health, Department of Histology and Embryology, Nanjing Medical University , Nanjing 211166,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9208-7538","authenticated-orcid":false,"given":"Yulan","family":"Wang (\u6c6a\u7389\u5170)","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics , Nanjing 211106,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0475-5705","authenticated-orcid":false,"given":"Xuejiang","family":"Guo (\u90ed\u96ea\u6c5f)","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Reproductive Medicine and Offspring Health, Department of Histology and Embryology, Nanjing Medical University , Nanjing 211166,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7445-4302","authenticated-orcid":false,"given":"Xiaofeng","family":"Song (\u5b8b\u6653\u5cf0)","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics , Nanjing 211106,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,12,2]]},"reference":[{"key":"2026091104564451900_qzaf121-B1","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.ymthe.2019.07.001","article-title":"Circular RNAs: a novel class of functional RNA molecules with a therapeutic perspective","volume":"27","author":"Santer","year":"2019","journal-title":"Mol Ther"},{"key":"2026091104564451900_qzaf121-B2","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1261\/rna.043687.113","article-title":"circBase: a database for circular RNAs","volume":"20","author":"Gla\u017ear","year":"2014","journal-title":"RNA"},{"key":"2026091104564451900_qzaf121-B3","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1093\/dnares\/dsx039","article-title":"Circular RNAs are abundant and dynamically expressed during embryonic muscle development in chickens","volume":"25","author":"Ouyang","year":"2018","journal-title":"DNA Res"},{"key":"2026091104564451900_qzaf121-B4","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1080\/15476286.2019.1591034","article-title":"Circular RNAs in human and vertebrate neural retinas","volume":"16","author":"Sun","year":"2019","journal-title":"RNA Biol"},{"key":"2026091104564451900_qzaf121-B5","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s13045-016-0370-2","article-title":"Circular RNAs in cancer: an emerging key player","volume":"10","author":"Dong","year":"2017","journal-title":"J Hematol Oncol"},{"key":"2026091104564451900_qzaf121-B6","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/nature11928","article-title":"Circular RNAs are a large class of animal RNAs with regulatory potency","volume":"495","author":"Memczak","year":"2013","journal-title":"Nature"},{"key":"2026091104564451900_qzaf121-B7","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13048-018-0381-4","article-title":"Circular RNAs: biogenesis, expression and their potential roles in reproduction","volume":"11","author":"Quan","year":"2018","journal-title":"J Ovarian Res"},{"key":"2026091104564451900_qzaf121-B8","doi-asserted-by":"crossref","first-page":"761698","DOI":"10.3389\/fmolb.2021.761698","article-title":"Diverse roles and therapeutic potentials of circular RNAs in urological cancers","volume":"8","author":"Wang","year":"2021","journal-title":"Front Mol Biosci"},{"key":"2026091104564451900_qzaf121-B9","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/s41576-019-0158-7","article-title":"The biogenesis, biology and characterization of circular RNAs","volume":"20","author":"Kristensen","year":"2019","journal-title":"Nat Rev Genet"},{"key":"2026091104564451900_qzaf121-B10","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1038\/s41419-021-03743-3","article-title":"CircRNAs: role in human diseases and potential use as biomarkers","volume":"12","author":"Verduci","year":"2021","journal-title":"Cell Death Dis"},{"key":"2026091104564451900_qzaf121-B11","doi-asserted-by":"crossref","first-page":"12060","DOI":"10.1038\/ncomms12060","article-title":"Comprehensive identification of internal structure and alternative splicing events in circular RNAs","volume":"7","author":"Gao","year":"2016","journal-title":"Nat Commun"},{"key":"2026091104564451900_qzaf121-B12","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/s41580-020-0243-y","article-title":"The expanding regulatory mechanisms and cellular functions of circular RNAs","volume":"21","author":"Chen","year":"2020","journal-title":"Nat Rev Mol Cell Biol"},{"key":"2026091104564451900_qzaf121-B13","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1016\/j.cell.2022.04.021","article-title":"Circular RNAs: characterization, cellular roles, and applications","volume":"185","author":"Liu","year":"2022","journal-title":"Cell"},{"key":"2026091104564451900_qzaf121-B14","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/nsmb.2959","article-title":"Exon-intron circular RNAs regulate transcription in the nucleus","volume":"22","author":"Li","year":"2015","journal-title":"Nat Struct Mol Biol"},{"key":"2026091104564451900_qzaf121-B15","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1261\/rna.457207","article-title":"Global analysis of alternative splicing during T-cell activation","volume":"13","author":"Ip","year":"2007","journal-title":"RNA"},{"key":"2026091104564451900_qzaf121-B16","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1186\/s12864-019-5572-x","article-title":"Differential isoform expression and alternative splicing in sex determination in mice","volume":"20","author":"Planells","year":"2019","journal-title":"BMC Genomics"},{"key":"2026091104564451900_qzaf121-B17","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/j.celrep.2015.12.081","article-title":"LRRTM3 regulates excitatory synapse development through alternative splicing and neurexin binding","volume":"14","author":"Um","year":"2016","journal-title":"Cell Rep"},{"key":"2026091104564451900_qzaf121-B18","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1146\/annurev-cancerbio-030617-050407","article-title":"Aberrant RNA splicing in cancer","volume":"3","author":"Escobar-Hoyos","year":"2019","journal-title":"Annu Rev Cancer Biol"},{"key":"2026091104564451900_qzaf121-B19","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1042\/EBC20200060","article-title":"Circular RNAs as microRNA sponges: evidence and controversies","volume":"65","author":"Jarlstad Olesen","year":"2021","journal-title":"Essays Biochem"},{"key":"2026091104564451900_qzaf121-B20","doi-asserted-by":"crossref","first-page":"e2012881118","DOI":"10.1073\/pnas.2012881118","article-title":"CircURI1 interacts with hnRNPM to inhibit metastasis by modulating alternative splicing in gastric cancer","volume":"118","author":"Wang","year":"2021","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2026091104564451900_qzaf121-B21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s12943-019-0996-0","article-title":"Genome-wide identification of cancer-specific alternative splicing in circRNA","volume":"18","author":"Feng","year":"2019","journal-title":"Mol Cancer"},{"key":"2026091104564451900_qzaf121-B22","doi-asserted-by":"crossref","first-page":"34985","DOI":"10.1038\/srep34985","article-title":"circRNADb: a comprehensive database for human circular RNAs with protein-coding annotations","volume":"6","author":"Chen","year":"2016","journal-title":"Sci Rep"},{"key":"2026091104564451900_qzaf121-B23","doi-asserted-by":"crossref","first-page":"D93","DOI":"10.1093\/nar\/gkab1036","article-title":"CircNet 2.0: an updated database for exploring circular RNA regulatory networks in cancers","volume":"50","author":"Chen","year":"2022","journal-title":"Nucleic Acids Res"},{"key":"2026091104564451900_qzaf121-B24","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.gpb.2018.08.001","article-title":"CIRCpedia v2: an updated database for comprehensive circular RNA annotation and expression comparison","volume":"16","author":"Dong","year":"2018","journal-title":"Genomics Proteomics Bioinformatics"},{"key":"2026091104564451900_qzaf121-B25","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1080\/15476286.2019.1600395","article-title":"Circbank: a comprehensive database for circRNA with standard nomenclature","volume":"16","author":"Liu","year":"2019","journal-title":"RNA Biol"},{"key":"2026091104564451900_qzaf121-B26","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/s13059-020-02018-y","article-title":"CircAtlas: an integrated resource of one million highly accurate circular RNAs from 1070 vertebrate transcriptomes","volume":"21","author":"Wu","year":"2020","journal-title":"Genome Biol"},{"key":"2026091104564451900_qzaf121-B27","doi-asserted-by":"crossref","first-page":"D925","DOI":"10.1093\/nar\/gkx863","article-title":"CSCD: a database for cancer-specific circular RNAs","volume":"46","author":"Xia","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"2026091104564451900_qzaf121-B28","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41467-020-20459-8","article-title":"isoCirc catalogs full-length circular RNA isoforms in human transcriptomes","volume":"12","author":"Xin","year":"2021","journal-title":"Nat Commun"},{"key":"2026091104564451900_qzaf121-B29","doi-asserted-by":"crossref","first-page":"100343","DOI":"10.1016\/j.xplc.2022.100343","article-title":"PlantcircBase 7.0: full-length transcripts and conservation of plant circRNAs","volume":"3","author":"Xu","year":"2022","journal-title":"Plant Commun"},{"key":"2026091104564451900_qzaf121-B30","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s13073-019-0614-1","article-title":"Reconstruction of full-length circular RNAs enables isoform-level quantification","volume":"11","author":"Zheng","year":"2019","journal-title":"Genome Med"},{"key":"2026091104564451900_qzaf121-B31","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.gpb.2019.03.004","article-title":"CircAST: full-length assembly and quantification of alternatively spliced isoforms in circular RNAs","volume":"17","author":"Wu","year":"2019","journal-title":"Genomics Proteomics Bioinformatics"},{"key":"2026091104564451900_qzaf121-B32","doi-asserted-by":"crossref","first-page":"e63","DOI":"10.1093\/nar\/gkl151","article-title":"Characterization of RNase R-digested cellular RNA source that consists of lariat and circular RNAs from pre-mRNA splicing","volume":"34","author":"Suzuki","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"2026091104564451900_qzaf121-B33","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/j.molcel.2015.03.027","article-title":"Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed","volume":"58","author":"Rybak-Wolf","year":"2015","journal-title":"Mol Cell"},{"key":"2026091104564451900_qzaf121-B34","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s13059-014-0571-3","article-title":"CIRI: an efficient and unbiased algorithm for de novo circular RNA identification","volume":"16","author":"Gao","year":"2015","journal-title":"Genome Biol"},{"key":"2026091104564451900_qzaf121-B35","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/bib\/bbq072","article-title":"PHAST and RPHAST: phylogenetic analysis with space\/time models","volume":"12","author":"Hubisz","year":"2011","journal-title":"Brief Bioinform"},{"key":"2026091104564451900_qzaf121-B36","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1093\/bioinformatics\/btu056","article-title":"bwtool: a tool for bigWig files","volume":"30","author":"Pohl","year":"2014","journal-title":"Bioinformatics"},{"key":"2026091104564451900_qzaf121-B37","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/bioinformatics\/btp698","article-title":"Fast and accurate long-read alignment with Burrows-Wheeler transform","volume":"26","author":"Li","year":"2010","journal-title":"Bioinformatics"},{"key":"2026091104564451900_qzaf121-B38","doi-asserted-by":"crossref","first-page":"e69457","DOI":"10.7554\/eLife.69457","article-title":"circFL-seq reveals full-length circular RNAs with rolling circular reverse transcription and nanopore sequencing","volume":"10","author":"Liu","year":"2021","journal-title":"Elife"},{"key":"2026091104564451900_qzaf121-B39","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1093\/bioinformatics\/btl158","article-title":"Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences","volume":"22","author":"Li","year":"2006","journal-title":"Bioinformatics"},{"key":"2026091104564451900_qzaf121-B40","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1182\/blood-2018-99-117815","article-title":"Genetic predisposition to therapy-related myeloid neoplasm by rare, deleterious germline variants in DNA repair pathway and myeloid driver genes","volume":"132","author":"Singhal","year":"2018","journal-title":"Blood"},{"key":"2026091104564451900_qzaf121-B41","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1136\/jnnp-2017-315929","article-title":"Mutations in BAG3 cause adult-onset Charcot-Marie-Tooth disease","volume":"89","author":"Shy","year":"2018","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2026091104564451900_qzaf121-B42","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.jgg.2018.07.006","article-title":"IRESfinder: identifying RNA internal ribosome entry site in eukaryotic cell using framed k-mer features","volume":"45","author":"Zhao","year":"2018","journal-title":"J Genet Genomics"},{"key":"2026091104564451900_qzaf121-B43","doi-asserted-by":"crossref","first-page":"e91","DOI":"10.1093\/nar\/gkw104","article-title":"SRAMP: prediction of mammalian N6-methyladenosine (m6A) sites based on sequence-derived features","volume":"44","author":"Zhou","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"2026091104564451900_qzaf121-B44","doi-asserted-by":"crossref","first-page":"e27836","DOI":"10.1371\/journal.pone.0027836","article-title":"SProtP: a web server to recognize those short-lived proteins based on sequence-derived features in human cells","volume":"6","author":"Song","year":"2011","journal-title":"PLoS One"},{"key":"2026091104564451900_qzaf121-B45","first-page":"310","article-title":"Prediction of glycosylation across the human proteome and the correlation to protein function","author":"Gupta","year":"2002","journal-title":"Pac Symp Biocomput"},{"key":"2026091104564451900_qzaf121-B46","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1093\/glycob\/cwm050","article-title":"NetCGlyc 1.0: prediction of mammalian C-mannosylation sites","volume":"17","author":"Julenius","year":"2007","journal-title":"Glycobiology"},{"key":"2026091104564451900_qzaf121-B47","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1038\/emboj.2013.79","article-title":"Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology","volume":"32","author":"Steentoft","year":"2013","journal-title":"EMBO J"},{"key":"2026091104564451900_qzaf121-B48","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/protein\/gzq094","article-title":"GPS 2.1: enhanced prediction of kinase-specific phosphorylation sites with an algorithm of motif length selection","volume":"24","author":"Xue","year":"2011","journal-title":"Protein Eng Des Sel"},{"key":"2026091104564451900_qzaf121-B49","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1186\/gb-2003-5-1-r1","article-title":"MicroRNA targets in","volume":"5","author":"Enright","year":"2003","journal-title":"Genome Biol"},{"key":"2026091104564451900_qzaf121-B50","doi-asserted-by":"crossref","first-page":"W451","DOI":"10.1093\/nar\/gkl243","article-title":"RNAhybrid: microRNA target prediction easy, fast and flexible","volume":"34","author":"Kr\u00fcger","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"2026091104564451900_qzaf121-B51","doi-asserted-by":"crossref","DOI":"10.1126\/science.aav1741","article-title":"The biochemical basis of microRNA targeting efficacy","volume":"366","author":"McGeary","year":"2019","journal-title":"Science"},{"key":"2026091104564451900_qzaf121-B52","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.molcel.2014.08.019","article-title":"circRNA biogenesis competes with pre-mRNA splicing","volume":"56","author":"Ashwal-Fluss","year":"2014","journal-title":"Mol Cell"},{"key":"2026091104564451900_qzaf121-B53","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s12943-017-0598-7","article-title":"Circular RNAs in human cancer","volume":"16","author":"Wang","year":"2017","journal-title":"Mol Cancer"},{"key":"2026091104564451900_qzaf121-B54","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1261\/rna.047126.114","article-title":"Circular RNAs: diversity of form and function","volume":"20","author":"Lasda","year":"2014","journal-title":"RNA"},{"key":"2026091104564451900_qzaf121-B55","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/s12870-023-04155-5","article-title":"Identification and characterization of CircRNA-associated CeRNA networks in moso bamboo under nitrogen stress","volume":"23","author":"Zhu","year":"2023","journal-title":"BMC Plant Biol"},{"key":"2026091104564451900_qzaf121-B56","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.isci.2019.08.058","article-title":"Long and repeat-rich intronic sequences favor circular RNA formation under conditions of reduced spliceosome activity","volume":"20","author":"Wang","year":"2019","journal-title":"iScience"},{"key":"2026091104564451900_qzaf121-B57","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.cell.2014.09.001","article-title":"Complementary sequence-mediated exon circularization","volume":"159","author":"Zhang","year":"2014","journal-title":"Cell"},{"key":"2026091104564451900_qzaf121-B58","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1261\/rna.035667.112","article-title":"Circular RNAs are abundant, conserved, and associated with ALU repeats","volume":"19","author":"Jeck","year":"2013","journal-title":"RNA"},{"key":"2026091104564451900_qzaf121-B59","doi-asserted-by":"crossref","first-page":"e69148","DOI":"10.7554\/eLife.69148","article-title":"Evolutionary dynamics of circular RNAs in primates","volume":"10","author":"Santos-Rodriguez","year":"2021","journal-title":"Elife"},{"key":"2026091104564451900_qzaf121-B60","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/s41598-020-79781-2","article-title":"Novel circRNA discovery in sheep shows evidence of high backsplice junction conservation","volume":"11","author":"Varela-Mart\u00ednez","year":"2021","journal-title":"Sci Rep"},{"key":"2026091104564451900_qzaf121-B61","doi-asserted-by":"crossref","first-page":"e67991","DOI":"10.7554\/eLife.67991","article-title":"Circular RNA repertoires are associated with evolutionarily young transposable elements","volume":"10","author":"Gruhl","year":"2021","journal-title":"Elife"},{"key":"2026091104564451900_qzaf121-B62","doi-asserted-by":"crossref","first-page":"D115","DOI":"10.1093\/nar\/gkad829","article-title":"FL-circAS: an integrative resource and analysis for full-length sequences and alternative splicing of circular RNAs with nanopore sequencing","volume":"52","author":"Chiang","year":"2024","journal-title":"Nucleic Acids Res"},{"key":"2026091104564451900_qzaf121-B63","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/j.gpb.2022.12.004","article-title":"Database Commons: a catalog of worldwide biological databases","volume":"21","author":"Ma","year":"2023","journal-title":"Genomics Proteomics Bioinformatics"}],"container-title":["Genomics, Proteomics &amp; Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/gpb\/advance-article-pdf\/doi\/10.1093\/gpbjnl\/qzaf121\/65672906\/qzaf121.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/gpb\/article-pdf\/24\/2\/qzaf121\/65672906\/qzaf121.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/gpb\/article-pdf\/24\/2\/qzaf121\/65672906\/qzaf121.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T08:57:00Z","timestamp":1789117020000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/gpb\/article\/doi\/10.1093\/gpbjnl\/qzaf121\/8362869"}},"subtitle":[],"editor":[{"given":"Fangqing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,12,2]]},"references-count":63,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6,26]]}},"URL":"https:\/\/doi.org\/10.1093\/gpbjnl\/qzaf121","relation":{},"ISSN":["1672-0229","2210-3244"],"issn-type":[{"value":"1672-0229","type":"print"},{"value":"2210-3244","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,2]]},"published":{"date-parts":[[2025,12,2]]},"article-number":"qzaf121"}}