{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T11:57:14Z","timestamp":1765886234366,"version":"3.37.3"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,1,5]],"date-time":"2021-01-05T00:00:00Z","timestamp":1609804800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1 OT2 OD026549","1 OT2 OD026554","1 OT2 OD026557","1 OT2 OD026556","1 OT2 OD026550","1 OT2 OD 026552","1 OT2 OD026553","1 OT2 OD026548","1 OT2 OD026551","1 OT2 OD026555","IAA #: AOD 1603"],"award-info":[{"award-number":["1 OT2 OD026549","1 OT2 OD026554","1 OT2 OD026557","1 OT2 OD026556","1 OT2 OD026550","1 OT2 OD 026552","1 OT2 OD026553","1 OT2 OD026548","1 OT2 OD026551","1 OT2 OD026555","IAA #: AOD 1603"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Federally Qualified Health Centers","award":["HHSN 263201600085U"],"award-info":[{"award-number":["HHSN 263201600085U"]}]},{"name":"Data and Research Center","award":["5 U2C OD023196"],"award-info":[{"award-number":["5 U2C OD023196"]}]},{"name":"Biobank","award":["1 U24 OD023121"],"award-info":[{"award-number":["1 U24 OD023121"]}]},{"name":"Participant Center","award":["U24 OD023176"],"award-info":[{"award-number":["U24 OD023176"]}]},{"name":"Participant Technology Systems Center","award":["1 U24 OD023163"],"award-info":[{"award-number":["1 U24 OD023163"]}]},{"name":"Communications and Engagement","award":["3 OT2 OD023205","3 OT2 OD023206"],"award-info":[{"award-number":["3 OT2 OD023205","3 OT2 OD023206"]}]},{"name":"Community Partners","award":["1 OT2 OD025277","3 OT2 OD025315","1 OT2 OD025337","1 OT2 OD025276"],"award-info":[{"award-number":["1 OT2 OD025277","3 OT2 OD025315","1 OT2 OD025337","1 OT2 OD025276"]}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23HL141447"],"award-info":[{"award-number":["K23HL141447"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institutes of Health Office of the Director","award":["1OT2OD026549"],"award-info":[{"award-number":["1OT2OD026549"]}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, And Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["K01HL143137"],"award-info":[{"award-number":["K01HL143137"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,3,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Family health history is important to clinical care and precision medicine. Prior studies show gaps in data collected from patient surveys and electronic health records (EHRs). The All of Us Research Program collects family history from participants via surveys and EHRs. This Demonstration Project aims to evaluate availability of family health history information within the publicly available data from All of Us and to characterize the data from both sources.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials and Methods<\/jats:title>\n                  <jats:p>Surveys were completed by participants on an electronic portal. EHR data was mapped to the Observational Medical Outcomes Partnership data model. We used descriptive statistics to perform exploratory analysis of the data, including evaluating a list of medically actionable genetic disorders. We performed a subanalysis on participants who had both survey and EHR data.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There were 54\u00a0872 participants with family history data. Of those, 26% had EHR data only, 63% had survey only, and 10.5% had data from both sources. There were 35\u00a0217 participants with reported family history of a medically actionable genetic disorder (9% from EHR only, 89% from surveys, and 2% from both). In the subanalysis, we found inconsistencies between the surveys and EHRs. More details came from surveys. When both mentioned a similar disease, the source of truth was unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Compiling data from both surveys and EHR can provide a more comprehensive source for family health history, but informatics challenges and opportunities exist. Access to more complete understanding of a person\u2019s family health history may provide opportunities for precision medicine.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jamia\/ocaa315","type":"journal-article","created":{"date-parts":[[2020,11,29]],"date-time":"2020-11-29T20:06:40Z","timestamp":1606680400000},"page":"695-703","source":"Crossref","is-referenced-by-count":18,"title":["Comparison of family health history in surveys vs electronic health record data mapped to the observational medical outcomes partnership data model in the <i>All of Us<\/i> Research Program"],"prefix":"10.1093","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1916-6521","authenticated-orcid":false,"given":"Robert M","family":"Cronin","sequence":"first","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"},{"name":"Department of Medicine, The Ohio State University, Columbus, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alese E","family":"Halvorson","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cassie","family":"Springer","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoke","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"Sulieman","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roxana","family":"Loperena-Cortes","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelsey","family":"Mayo","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J","family":"Carroll","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingxia","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, 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