{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T02:38:49Z","timestamp":1775615929570,"version":"3.50.1"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"4","funder":[{"name":"Veterans Health Administration HSR&D Merit Review","award":["1 I01 HX002922-01A2"],"award-info":[{"award-number":["1 I01 HX002922-01A2"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We conducted an implementation planning process during the pilot phase of a pragmatic trial, which tests an intervention guided by artificial intelligence (AI) analytics sourced from noninvasive monitoring data in heart failure patients (LINK-HF2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A mixed-method analysis was conducted at 2 pilot sites. Interviews were conducted with 12 of 27 enrolled patients and with 13 participating clinicians. iPARIHS constructs were used for interview construction to identify workflow, communication patterns, and clinician\u2019s beliefs. Interviews were transcribed and analyzed using inductive coding protocols to identify key themes. Behavioral response data from the AI-generated notifications were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Clinicians responded to notifications within 24 hours in 95% of instances, with 26.7% resulting in clinical action. Four implementation themes emerged: (1) High anticipatory expectations for reliable patient communications, reduced patient burden, and less proactive provider monitoring. (2) The AI notifications required a differential and tailored balance of trust and action advice related to role. (3) Clinic experience with other home-based programs influenced utilization. (4) Responding to notifications involved significant effort, including electronic health record (EHR) review, patient contact, and consultation with other clinicians.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Clinician\u2019s use of AI data is a function of beliefs regarding the trustworthiness and usefulness of the data, the degree of autonomy in professional roles, and the cognitive effort involved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The implementation planning analysis guided development of strategies that addressed communication technology, patient education, and EHR integration to reduce clinician and patient burden in the subsequent main randomized phase of the trial. Our results provide important insights into the unique implications of implementing AI analytics into clinical workflow.<\/jats:p><\/jats:sec>","DOI":"10.1093\/jamia\/ocae017","type":"journal-article","created":{"date-parts":[[2024,2,11]],"date-time":"2024-02-11T15:39:45Z","timestamp":1707665985000},"page":"919-928","source":"Crossref","is-referenced-by-count":10,"title":["Artificial intelligence predictive analytics in heart failure: results of the pilot phase of a pragmatic randomized clinical trial"],"prefix":"10.1093","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9369-0782","authenticated-orcid":false,"given":"Konstantinos","family":"Sideris","sequence":"first","affiliation":[{"name":"Cardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center , Salt Lake City, UT 84148, United States"},{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah , Salt Lake City, UT 84112, United States"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8297-2860","authenticated-orcid":false,"given":"Charlene R","family":"Weir","sequence":"additional","affiliation":[{"name":"Cardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center , Salt Lake City, UT 84148, United States"},{"name":"Department of Biomedical Informatics, School of Medicine, University of Utah , Salt Lake City, UT 84108, United States"}]},{"given":"Carsten","family":"Schmalfuss","sequence":"additional","affiliation":[{"name":"Cardiology Section, Medical Service, Malcom Randall VA Medical Center , Gainesville, FL 32608, United States"},{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, University of Florida College of Medicine , Gainesville, FL 32610, United States"}]},{"given":"Heather","family":"Hanson","sequence":"additional","affiliation":[{"name":"Cardiology Section, Medical Service, George E. 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Wahlen Department of Veterans Affairs Medical Center , Salt Lake City, UT 84148, United States"},{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah , Salt Lake City, UT 84112, United States"}]},{"given":"Richard","family":"Schofield","sequence":"additional","affiliation":[{"name":"Cardiology Section, Medical Service, Malcom Randall VA Medical Center , Gainesville, FL 32608, United States"},{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, University of Florida College of Medicine , Gainesville, FL 32610, United States"}]},{"given":"Karen","family":"Larimer","sequence":"additional","affiliation":[{"name":"PhysIQ, Inc. , Chicago, IL 60563, United States"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9415-1245","authenticated-orcid":false,"given":"Christos P","family":"Kyriakopoulos","sequence":"additional","affiliation":[{"name":"Cardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center , Salt Lake City, UT 84148, United States"},{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah , Salt Lake City, UT 84112, United States"}]},{"given":"Iosif","family":"Taleb","sequence":"additional","affiliation":[{"name":"Cardiology Section, Medical Service, George E. Wahlen Department of Veterans Affairs Medical Center , Salt Lake City, UT 84148, United States"},{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah , Salt Lake City, UT 84112, United States"}]},{"given":"Lina","family":"Brinker","sequence":"additional","affiliation":[{"name":"Cardiology Section, Medical Service, George E. 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