{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T13:06:39Z","timestamp":1771851999542,"version":"3.50.1"},"reference-count":56,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH118151"],"award-info":[{"award-number":["R01MH118151"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Tennessee Center for AIDS Research","award":["P30 AI110527"],"award-info":[{"award-number":["P30 AI110527"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To determine the efficacy of the mLab App, a mobile-delivered HIV prevention intervention to increase HIV self-testing in MSM and TGW.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials and methods<\/jats:title>\n                  <jats:p>This was a randomized (2:2:1) clinical trial of the efficacy the mLab App as compared to standard of care vs mailed home HIV test arm among 525 MSM and TGW aged 18-29\u00a0years to increase HIV testing.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The mLab App arm participants demonstrated an increase from 35.1% reporting HIV testing in the prior 6\u00a0months compared to 88.5% at 6\u00a0months. In contrast, 28.8% of control participants reported an HIV test at baseline, which only increased to 65.1% at 6\u00a0months. In a generalized linear mixed model estimating this change and controlling for multiple observations of participants, this equated to control participants reporting a 61.2% smaller increase in HIV testing relative to mLab participants (P\u2009=\u2009.001) at 6\u00a0months. This difference was maintained at 12\u00a0months with control participants reporting an 82.6% smaller increase relative to mLab App participants (P\u2009&amp;lt;\u2009.001) from baseline to 12\u00a0months.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion and conclusion<\/jats:title>\n                  <jats:p>Findings suggest that the mLab App is well-supported, evidence-based, behavioral risk-reduction intervention for increasing HIV testing rates as compared to the standard of care, suggesting that this may be a useful behavioral risk-reduction intervention for increasing HIV testing among young MSM.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Trial registration<\/jats:title>\n                  <jats:p>This trial was registered with Clinicaltrials.gov NCT03803683.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jamia\/ocae261","type":"journal-article","created":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T13:50:58Z","timestamp":1732024258000},"page":"275-284","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy of the mLab App: a randomized clinical trial for increasing HIV testing uptake using mobile technology"],"prefix":"10.1093","volume":"32","author":[{"given":"Rebecca","family":"Schnall","sequence":"first","affiliation":[{"name":"School of Nursing, Columbia University , New York, NY 10032,","place":["United States"]},{"name":"Department of Population and Family Health, Columbia University, Mailman School of Public Health , New York, NY 10032,","place":["United States"]}]},{"given":"Thomas Foster","family":"Scherr","sequence":"additional","affiliation":[{"name":"Department of Chemistry, College of Arts and Science, Vanderbilt University , Nashville, TN 37235,","place":["United States"]}]},{"given":"Lisa M","family":"Kuhns","sequence":"additional","affiliation":[{"name":"Division of Adolescent & Young Adult Medicine, Ann & Robert H. 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