{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T10:58:52Z","timestamp":1780916332651,"version":"3.54.1"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,11,23]],"date-time":"2024-11-23T00:00:00Z","timestamp":1732320000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000133","name":"Agency for Healthcare Quality and Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000133","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100006093","name":"Patient Centered Outcomes Research Institute","doi-asserted-by":"crossref","award":["P30HS029744"],"award-info":[{"award-number":["P30HS029744"]}],"id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100006093","name":"Patient Centered Outcomes Research Institute","doi-asserted-by":"crossref","award":["P30HS029742"],"award-info":[{"award-number":["P30HS029742"]}],"id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100006093","name":"Patient Centered Outcomes Research Institute","doi-asserted-by":"crossref","award":["P30HS029767"],"award-info":[{"award-number":["P30HS029767"]}],"id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>There is rapidly growing interest in learning health systems (LHSs) nationally and globally. While the critical role of informatics is recognized, the informatics community has been relatively slow to formalize LHS as a priority area.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials and Methods<\/jats:title>\n                  <jats:p>We compiled results from a short survey of LHS leaders and American Medical Informatics Association (AMIA) members, discussion from an LHS reception at the AMIA annual meeting, and a follow-up survey to inform priorities at the intersection of LHS and informatics.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We present opportunities between informatics and LHS which fell into themes of: Understanding and Context, Shared Resources, Collaboration, Education, Data, Evaluation, and Patient Centeredness. Immediate LHS informatics priorities identified include establishing informatics LHS forum(s), case reports of LHS informatics successes and failures, LHS informatics education resources, and improved understanding of LHS principles in informatics.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Increased informatics and LHS alignment is critical for advancing this transformative national priority.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jamia\/ocae281","type":"journal-article","created":{"date-parts":[[2024,11,23]],"date-time":"2024-11-23T18:00:02Z","timestamp":1732384802000},"page":"253-257","source":"Crossref","is-referenced-by-count":6,"title":["Opportunities for the informatics community to advance learning health systems"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8051-8102","authenticated-orcid":false,"given":"Melissa A","family":"Gunderson","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Minnesota , Minneapolis, MN 55455,","place":["United States"]},{"name":"Center for Learning Health System Sciences, University of Minnesota , Minneapolis, MN 55455,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7733-0847","authenticated-orcid":false,"given":"Peter","family":"Emb\u00ed","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University , Nashville, TN 37203,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3395-5199","authenticated-orcid":false,"given":"Charles P","family":"Friedman","sequence":"additional","affiliation":[{"name":"Department of Learning Health Sciences, University of Michigan , Ann Arbor, MI 48109,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5193-1663","authenticated-orcid":false,"given":"Genevieve B","family":"Melton","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Minnesota , Minneapolis, MN 55455,","place":["United States"]},{"name":"Center for Learning Health System Sciences, University of Minnesota , Minneapolis, MN 55455,","place":["United States"]},{"name":"Institute for Health Informatics, University of Minnesota , Minneapolis, MN 55455,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,11,23]]},"reference":[{"key":"2024121616113780700_ocae281-B1","volume-title":"The Learning Healthcare System: Workshop Summary","author":"Institute of Medicine (US) Roundtable on Evidence-Based Medicine","year":"2007"},{"key":"2024121616113780700_ocae281-B2"},{"key":"2024121616113780700_ocae281-B3","doi-asserted-by":"crossref","first-page":"e10328","DOI":"10.1002\/lrh2.10328","article-title":"What is unique about learning health systems?","volume":"6","author":"Friedman","year":"2022","journal-title":"Learn Health Syst"},{"key":"2024121616113780700_ocae281-B4","doi-asserted-by":"crossref","first-page":"e10315","DOI":"10.1002\/lrh2.10315","article-title":"A framework for understanding, designing, developing and evaluating learning health systems","volume":"7","author":"Foley","year":"2023","journal-title":"Learn Health Syst"},{"key":"2024121616113780700_ocae281-B5","doi-asserted-by":"crossref","first-page":"e10342","DOI":"10.1002\/lrh2.10342","article-title":"Training the next generation of learning health system scientists","volume":"6","author":"Lozano","year":"2022","journal-title":"Learn Health Syst"},{"key":"2024121616113780700_ocae281-B6","doi-asserted-by":"crossref","first-page":"e10287","DOI":"10.1002\/lrh2.10287","article-title":"Clarifying the concept of a learning health system for healthcare delivery organizations: implications from a qualitative analysis of the scientific literature","volume":"6","author":"Easterling","year":"2022","journal-title":"Learn Health Syst"},{"key":"2024121616113780700_ocae281-B7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.mayocpiqo.2020.10.004","article-title":"Learning health system in crisis: lessons from the COVID-19 pandemic","volume":"5","author":"Romanelli","year":"2021","journal-title":"Mayo Clin Proc Innov Qual Outcomes"},{"key":"2024121616113780700_ocae281-B8","doi-asserted-by":"crossref","first-page":"e10309","DOI":"10.1002\/lrh2.10309","article-title":"Better together: integrating biomedical informatics and healthcare IT operations to create a learning health system during the COVID-19 pandemic","volume":"6","author":"Payne","year":"2022","journal-title":"Learn Health Syst"},{"key":"2024121616113780700_ocae281-B9","doi-asserted-by":"crossref","first-page":"e076175","DOI":"10.1136\/bmj-2023-076175","article-title":"Data to knowledge to improvement: creating the learning health system","volume":"384","author":"McDonald","year":"2024","journal-title":"BMJ"},{"key":"2024121616113780700_ocae281-B10","doi-asserted-by":"crossref","first-page":"e10258","DOI":"10.1002\/lrh2.10258","article-title":"A roadmap to operationalize and evaluate impact in a learning health system","volume":"5","author":"Allen","year":"2021","journal-title":"Learn Health Syst"},{"key":"2024121616113780700_ocae281-B11","first-page":"397","article-title":"How are leading research institutions engaging with data sharing tools and programs?","volume":"2023","author":"Hall","year":"2023","journal-title":"AMIA Annu Symp 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