{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T01:30:18Z","timestamp":1779931818312,"version":"3.53.1"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2016,11,7]],"date-time":"2016-11-07T00:00:00Z","timestamp":1478476800000},"content-version":"vor","delay-in-days":516,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Objective To share approaches and innovations adopted to deliver a relatively inexpensive clinical data management (CDM) framework within a low-income setting that aims to deliver quality pediatric data useful for supporting research, strengthening the information culture and informing improvement efforts in local clinical practice.<\/jats:p>\n               <jats:p>Materials and methods The authors implemented a CDM framework to support a Clinical Information Network (CIN) using Research Electronic Data Capture (REDCap), a noncommercial software solution designed for rapid development and deployment of electronic data capture tools. It was used for collection of standardized data from case records of multiple hospitals\u2019 pediatric wards. R, an open-source statistical language, was used for data quality enhancement, analysis, and report generation for the hospitals.<\/jats:p>\n               <jats:p>Results In the first year of CIN, the authors have developed innovative solutions to support the implementation of a secure, rapid pediatric data collection system spanning 14 hospital sites with stringent data quality checks. Data have been collated on over 37 000 admission episodes, with considerable improvement in clinical documentation of admissions observed. Using meta-programming techniques in R, coupled with branching logic, randomization, data lookup, and Application Programming Interface (API) features offered by REDCap, CDM tasks were configured and automated to ensure quality data was delivered for clinical improvement and research use.<\/jats:p>\n               <jats:p>Conclusion A low-cost clinically focused but geographically dispersed quality CDM (Clinical Data Management) in a long-term, multi-site, and real world context can be achieved and sustained and challenges can be overcome through thoughtful design and implementation of open-source tools for handling data and supporting research.<\/jats:p>","DOI":"10.1093\/jamia\/ocv028","type":"journal-article","created":{"date-parts":[[2015,6,11]],"date-time":"2015-06-11T11:04:18Z","timestamp":1434020658000},"page":"184-192","source":"Crossref","is-referenced-by-count":67,"title":["Innovating to enhance clinical data management using non-commercial and open source solutions across a multi-center network supporting inpatient pediatric care and research in Kenya"],"prefix":"10.1093","volume":"23","author":[{"given":"Timothy","family":"Tuti","sequence":"first","affiliation":[{"name":"KEMRI-Wellcome Trust Research Programme, P. O. Box 43640 - 00100, Nairobi, Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Bitok","sequence":"additional","affiliation":[{"name":"KEMRI-Wellcome Trust Research Programme, P. O. Box 43640 - 00100, Nairobi, Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Paton","sequence":"additional","affiliation":[{"name":"Nuffield Department of Medicine, University of Oxford John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boniface","family":"Makone","sequence":"additional","affiliation":[{"name":"KEMRI-Wellcome Trust Research Programme, P. O. Box 43640 - 00100, Nairobi, Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Malla","sequence":"additional","affiliation":[{"name":"KEMRI-Wellcome Trust Research Programme, P. O. 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