{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T19:28:15Z","timestamp":1776108495896,"version":"3.50.1"},"reference-count":73,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Objective To review and evaluate available software tools for electronic health record\u2013driven phenotype authoring in order to identify gaps and needs for future development.<\/jats:p>\n               <jats:p>Materials and Methods Candidate phenotype authoring tools were identified through (1) literature search in four publication databases (PubMed, Embase, Web of Science, and Scopus) and (2) a web search. A collection of tools was compiled and reviewed after the searches. A survey was designed and distributed to the developers of the reviewed tools to discover their functionalities and features.<\/jats:p>\n               <jats:p>Results Twenty-four different phenotype authoring tools were identified and reviewed. Developers of 16 of these identified tools completed the evaluation survey (67% response rate). The surveyed tools showed commonalities but also varied in their capabilities in algorithm representation, logic functions, data support and software extensibility, search functions, user interface, and data outputs.<\/jats:p>\n               <jats:p>Discussion Positive trends identified in the evaluation included: algorithms can be represented in both computable and human readable formats; and most tools offer a web interface for easy access. However, issues were also identified: many tools were lacking advanced logic functions for authoring complex algorithms; the ability to construct queries that leveraged un-structured data was not widely implemented; and many tools had limited support for plug-ins or external analytic software.<\/jats:p>\n               <jats:p>Conclusions Existing phenotype authoring tools could enable clinical researchers to work with electronic health record data more efficiently, but gaps still exist in terms of the functionalities of such tools. The present work can serve as a reference point for the future development of similar tools.<\/jats:p>","DOI":"10.1093\/jamia\/ocv070","type":"journal-article","created":{"date-parts":[[2015,7,30]],"date-time":"2015-07-30T01:11:07Z","timestamp":1438218667000},"page":"1251-1260","source":"Crossref","is-referenced-by-count":29,"title":["Review and evaluation of electronic health records-driven phenotype algorithm authoring tools for clinical and translational research"],"prefix":"10.1093","volume":"22","author":[{"given":"Jie","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luke V","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela L","family":"Shaw","sequence":"additional","affiliation":[{"name":"Galter Health Science Library, Clinical and Translational Sciences Institute (NUCATS), Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoqian","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard C","family":"Kiefer","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan","family":"Mo","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer A","family":"Pacheco","sequence":"additional","affiliation":[{"name":"Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Speltz","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Information Systems, University of Maryland, Baltimore County (UMBC), Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua C","family":"Denny","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyotishman","family":"Pathak","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William K","family":"Thompson","sequence":"additional","affiliation":[{"name":"Center for Biomedical Research Informatics, NorthShore University Health System, Evanston, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enid","family":"Montague","sequence":"additional","affiliation":[{"name":"Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2015,7,29]]},"reference":[{"issue":"1","key":"2020110613021280900_ocv070-B1","first-page":"1","article-title":"Toward a national framework for the secondary use of health data: an American Medical Informatics Association White Paper","volume":"14","author":"Safran","year":"2007","journal-title":"JAMIA."},{"issue":"3","key":"2020110613021280900_ocv070-B2","first-page":"316","article-title":"Clinical research informatics: challenges, opportunities and definition for an emerging domain","volume":"16","author":"Embi","year":"2009","journal-title":"JAMIA."},{"key":"2020110613021280900_ocv070-B3","first-page":"181","article-title":"Research networks: can we use data from GPs' electronic health records?","volume":"124","author":"De Clercq","year":"2006","journal-title":"Stud Health Technol Inform"},{"issue":"9","key":"2020110613021280900_ocv070-B4","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1101\/gr.094615.109","article-title":"Instrumenting the health care enterprise for discovery research in the genomic era","volume":"19","author":"Murphy","year":"2009","journal-title":"Genome Res."},{"issue":"1","key":"2020110613021280900_ocv070-B5","first-page":"117","article-title":"Next-generation phenotyping of electronic health records","volume":"20","author":"Hripcsak","year":"2012","journal-title":"JAMIA."},{"issue":"10","key":"2020110613021280900_ocv070-B6","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1038\/nrg1919","article-title":"Genes, environment and the value of prospective cohort studies","volume":"7","author":"Manolio","year":"2006","journal-title":"Nat Rev Genet."},{"issue":"7145","key":"2020110613021280900_ocv070-B7","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nature05911","article-title":"Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls","volume":"447","author":"Burton","year":"2007","journal-title":"Nature."},{"issue":"7130","key":"2020110613021280900_ocv070-B8","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/nature05616","article-title":"A genome-wide association study identifies novel risk loci for type 2 diabetes","volume":"445","author":"Sladek","year":"2007","journal-title":"Nature."},{"issue":"3","key":"2020110613021280900_ocv070-B9","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/clpt.2008.89","article-title":"Development of a large-scale de-identified DNA biobank to enable personalized medicine","volume":"84","author":"Roden","year":"2008","journal-title":"Clin Pharmacol Therap."},{"issue":"8","key":"2020110613021280900_ocv070-B10","doi-asserted-by":"crossref","first-page":"A466","DOI":"10.1289\/ehp.114-a466","article-title":"Gene\u2013environment studies: who, how, when, and where?","volume":"114","author":"Spivey","year":"2006","journal-title":"Environ Health Persp."},{"issue":"2","key":"2020110613021280900_ocv070-B11","first-page":"124","article-title":"Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)","volume":"17","author":"Murphy","year":"2010","journal-title":"JAMIA."},{"issue":"e2","key":"2020110613021280900_ocv070-B12","first-page":"e226","article-title":"Electronic health records based phenotyping in next-generation clinical trials: a perspective from the NIH Health Care Systems Collaboratory","volume":"20","author":"Richesson","year":"2013","journal-title":"JAMIA."},{"key":"2020110613021280900_ocv070-B13","article-title":"Modeling and executing electronic health records driven phenotyping algorithms using the NQF Quality Data Model and JBoss\u00ae Drools engine","author":"Li","year":"2012","journal-title":"AMIA Ann Symp Proc."},{"issue":"12","key":"2020110613021280900_ocv070-B14","doi-asserted-by":"crossref","first-page":"e32","DOI":"10.1016\/j.amjmed.2010.10.006","article-title":"Comparative effectiveness research and medical informatics","volume":"123","author":"D'Avolio","year":"2010","journal-title":"Am J Med."},{"issue":"2","key":"2020110613021280900_ocv070-B15","first-page":"379","article-title":"Harvest: an open platform for developing web-based biomedical data discovery and reporting applications","volume":"21","author":"Pennington","year":"2013","journal-title":"JAMIA."},{"issue":"12","key":"2020110613021280900_ocv070-B16","doi-asserted-by":"crossref","first-page":"e1002823","DOI":"10.1371\/journal.pcbi.1002823","article-title":"Mining electronic health records in the genomics era","volume":"8","author":"Denny","year":"2012","journal-title":"PLoS Comput Biol."},{"key":"2020110613021280900_ocv070-B17","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/978-0-387-39940-9_120","article-title":"Data warehousing for clinical research","author":"Murphy","year":"2009","journal-title":"Encyclopedia of database systems"},{"key":"2020110613021280900_ocv070-B18","doi-asserted-by":"crossref","DOI":"10.1002\/0470867167.ch36","article-title":"The data deluge: An e-science perspective","volume-title":"Grid Computing: Making the Global Infrastructure a Reality","author":"Hey","year":"2003"},{"issue":"1","key":"2020110613021280900_ocv070-B19","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jbi.2009.06.001","article-title":"Evaluation of a flowchart-based EHR query system: A case study of RetroGuide","volume":"43","author":"Huser","year":"2010","journal-title":"J Biomed Inform."},{"issue":"6","key":"2020110613021280900_ocv070-B20","first-page":"511","article-title":"Data extraction and ad hoc query of an entity\u2014Attribute\u2014Value database","volume":"5","author":"Nadkarni","year":"1998","journal-title":"JAMIA."},{"key":"2020110613021280900_ocv070-B21","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.jbi.2014.07.006","article-title":"Modular design, application architecture, and usage of a self-service model for enterprise data delivery: The Duke Enterprise Data Unified Content Explorer (DEDUCE)","volume":"52","author":"Horvath","year":"2014","journal-title":"J Biomed Inform."},{"key":"2020110613021280900_ocv070-B22","article-title":"A visual interface designed for novice users to find research patient cohorts in a large biomedical database","author":"Murphy","year":"2003","journal-title":"AMIA Ann Symp Proc."},{"key":"2020110613021280900_ocv070-B23","article-title":"VISAGE: a query interface for clinical research","author":"Zhang","year":"2010","journal-title":"AMIA Summits Transl Sci Proc."},{"key":"2020110613021280900_ocv070-B24","article-title":"Characterization of the biomedical query mediation process","author":"Hruby","year":"2013","journal-title":"AMIA Summits Transl Sci Proc."},{"issue":"2","key":"2020110613021280900_ocv070-B25","first-page":"221","article-title":"A review of approaches to identifying patient phenotype cohorts using electronic health records","volume":"21","author":"Shivade","year":"2013","journal-title":"JAMIA."},{"issue":"5","key":"2020110613021280900_ocv070-B26","first-page":"624","article-title":"The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories","volume":"16","author":"Weber","year":"2009","journal-title":"JAMIA."},{"key":"2020110613021280900_ocv070-B27"},{"key":"2020110613021280900_ocv070-B28","author":"Narus"},{"key":"2020110613021280900_ocv070-B29"},{"issue":"1","key":"2020110613021280900_ocv070-B30","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1145\/1656274.1656280","article-title":"KNIME-the Konstanz information miner: version 2.0 and beyond","volume":"11","author":"Berthold","year":"2009","journal-title":"ACM SIGKDD Explorations Newsletter."},{"key":"2020110613021280900_ocv070-B31","author":"Rasmussen"},{"key":"2020110613021280900_ocv070-B32","author":"Mo"},{"issue":"2","key":"2020110613021280900_ocv070-B33","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2014A metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inform."},{"issue":"1","key":"2020110613021280900_ocv070-B34","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1472-6947-12-47","article-title":"Computational challenges and human factors influencing the design and use of clinical research participant eligibility pre-screening tools","volume":"12","author":"Pressler","year":"2012","journal-title":"BMC Med Informat Decis Mak."},{"key":"2020110613021280900_ocv070-B35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jbi.2013.11.004","article-title":"The National Institutes of Health\u2019s Biomedical Translational Research Information System (BTRIS): Design, contents, functionality and experience to date","volume":"52","author":"Cimino","year":"2014","journal-title":"J Biomed Inform."},{"issue":"Pt 2","key":"2020110613021280900_ocv070-B36","first-page":"1299","article-title":"The clinical research data repository of the US National Institutes of Health","volume":"160","author":"Cimino","year":"2010","journal-title":"Stud Health Technol Inform."},{"key":"2020110613021280900_ocv070-B37","first-page":"632","article-title":"Developing a self-service query interface for re-using de-identified electronic health record data","volume":"192","author":"Cimino","year":"2013","journal-title":"Stud Health Technol Inform."},{"issue":"1","key":"2020110613021280900_ocv070-B38","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/rheumatology\/keq309","article-title":"DANBIO\u2014powerful research database and electronic patient record","volume":"50","author":"Hetland","year":"2011","journal-title":"Rheumatology."},{"issue":"3","key":"2020110613021280900_ocv070-B39","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1109\/TITB.2004.832550","article-title":"DBMap: a space-conscious data visualization and knowledge discovery framework for biomedical data warehouse","volume":"8","author":"Zhang","year":"2004","journal-title":"Inform Technol Biomed, IEEE Transactions on."},{"issue":"2","key":"2020110613021280900_ocv070-B40","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jbi.2010.11.008","article-title":"The DEDUCE Guided Query tool: providing simplified access to clinical data for research and quality improvement","volume":"44","author":"Horvath","year":"2011","journal-title":"J Biomed Inform."},{"key":"2020110613021280900_ocv070-B41","first-page":"534","article-title":"The Electronic Healthcare Record for Clinical Research (EHR4CR) information model and terminology","volume":"180","author":"Ouagne","year":"2012","journal-title":"Stud Health Technol Inform."},{"issue":"4","key":"2020110613021280900_ocv070-B42","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3414\/ME13-01-0134","article-title":"Piloting the EHR4CR feasibility platform across Europe","volume":"53","author":"Doods","year":"2014","journal-title":"Methods Inform Med."},{"issue":"1","key":"2020110613021280900_ocv070-B43","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3122\/jabfm.19.1.93","article-title":"The Electronic Primary Care Research Network (ePCRN): a new era in practice-based research","volume":"19","author":"Peterson","year":"2006","journal-title":"J Am Board Fam Med."},{"key":"2020110613021280900_ocv070-B44","article-title":"ePCRN-IDEA2: An Agent-Based System for Large-Scale Clinical Trial Recruitment","author":"Feyisetan"},{"issue":"1","key":"2020110613021280900_ocv070-B45","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1370\/afm.1313","article-title":"Envisioning a learning health care system: the electronic primary care research network, a case study","volume":"10","author":"Delaney","year":"2012","journal-title":"Ann Fam Med."},{"key":"2020110613021280900_ocv070-B46","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jbi.2014.02.003","article-title":"Secondary use of clinical data: the Vanderbilt approach","volume":"52","author":"Danciu","year":"2014","journal-title":"J Biomed Inform."},{"key":"2020110613021280900_ocv070-B47","article-title":"Semantic ETL into i2b2 with Eureka!","author":"Post","year":"2013","journal-title":"AMIA Summits Transl Sci Proc."},{"issue":"7","key":"2020110613021280900_ocv070-B48","doi-asserted-by":"crossref","first-page":"e161","DOI":"10.2196\/jmir.3446","article-title":"Employing computers for the recruitment into clinical trials: a comprehensive systematic review","volume":"16","author":"K\u00f6pcke","year":"2014","journal-title":"J Med Internet Res."},{"issue":"1","key":"2020110613021280900_ocv070-B49","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1186\/1471-2105-14-180","article-title":"Computational framework to support integration of biomolecular and clinical data within a translational approach","volume":"14","author":"Miyoshi","year":"2013","journal-title":"BMC Bioinformatics."},{"key":"2020110613021280900_ocv070-B50"},{"key":"2020110613021280900_ocv070-B51","author":"Peissig"},{"key":"2020110613021280900_ocv070-B52","author":"Huser"},{"issue":"1","key":"2020110613021280900_ocv070-B53","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/1471-2288-11-43","article-title":"Implementation of workflow engine technology to deliver basic clinical decision support functionality","volume":"11","author":"Huser","year":"2011","journal-title":"BMC Med Res Methodol."},{"issue":"3","key":"2020110613021280900_ocv070-B54","doi-asserted-by":"crossref","first-page":"267","DOI":"10.2174\/157489312802460730","article-title":"SemanticDB: a semantic Web infrastructure for clinical research and quality reporting","volume":"7","author":"Pierce","year":"2012","journal-title":"Curr Bioinformatics."},{"key":"2020110613021280900_ocv070-B55","article-title":"STRIDE\u2013An integrated standards-based translational research informatics platform","author":"Lowe","year":"2009","journal-title":"AMIA Annual Symposium Proceedings."},{"key":"2020110613021280900_ocv070-B56","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/930362","article-title":"CrcTRP: a translational research platform for colorectal cancer","author":"Deng","year":"2013","journal-title":"Comput Math Methods Med."},{"issue":"2","key":"2020110613021280900_ocv070-B57","first-page":"292","article-title":"Exploiting the potential of large databases of electronic health records for research using rapid search algorithms and an intuitive query interface","volume":"21","author":"Tate","year":"2014","journal-title":"JAMIA."},{"issue":"12","key":"2020110613021280900_ocv070-B58","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.compbiomed.2005.08.003","article-title":"Data mining and clinical data repositories: Insights from a 667,000 patient data set","volume":"36","author":"Mullins","year":"2006","journal-title":"Comput Biol Med."},{"key":"2020110613021280900_ocv070-B59","first-page":"1216","article-title":"Web-accessible patient data warehouse at the University of Virginia","volume":"1999","author":"Scully","year":"1999","journal-title":"Proc AMIA Symp."},{"issue":"1","key":"2020110613021280900_ocv070-B60","first-page":"164","article-title":"Identifying clinical\/translational research cohorts: ascertainment via querying an integrated multi-source database","volume":"20","author":"Hurdle","year":"2012","journal-title":"JAMIA."},{"issue":"e2","key":"2020110613021280900_ocv070-B61","first-page":"e288","article-title":"Leveraging electronic healthcare record standards and semantic web technologies for the identification of patient cohorts","volume":"20","author":"Fern\u00e1ndez-Breis","year":"2013","journal-title":"JAMIA."},{"key":"2020110613021280900_ocv070-B62"},{"key":"2020110613021280900_ocv070-B63"},{"key":"2020110613021280900_ocv070-B64","author":"Rasmussen"},{"issue":"1","key":"2020110613021280900_ocv070-B65","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1755-8794-4-13","article-title":"The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies","volume":"4","author":"McCarty","year":"2011","journal-title":"BMC Med Genomics."},{"key":"2020110613021280900_ocv070-B66","first-page":"274","article-title":"Analyzing the heterogeneity and complexity of Electronic Health Record oriented phenotyping algorithms","volume":"2011","author":"Conway","year":"2011","journal-title":"AMIA Annu Symp Proc."},{"issue":"6","key":"2020110613021280900_ocv070-B67","doi-asserted-by":"crossref","first-page":"e96443","DOI":"10.1371\/journal.pone.0096443","article-title":"Dynamical phenotyping: using temporal analysis of clinically collected physiologic data to stratify populations","volume":"9","author":"Albers","year":"2014","journal-title":"PloS One."},{"issue":"e2","key":"2020110613021280900_ocv070-B68","first-page":"e334","article-title":"Automated extraction of clinical traits of multiple sclerosis in electronic medical records","volume":"20","author":"Davis","year":"2013","journal-title":"JAMIA."},{"issue":"e2","key":"2020110613021280900_ocv070-B69","first-page":"e349","article-title":"Billing code algorithms to identify cases of peripheral artery disease from administrative data","volume":"20","author":"Fan","year":"2013","journal-title":"JAMIA."},{"issue":"1","key":"2020110613021280900_ocv070-B70","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1197\/j.aem.2005.07.038","article-title":"Accuracy of Mild Traumatic Brain Injury Case Ascertainment Using ICD - 9 Codes","volume":"13","author":"Bazarian","year":"2006","journal-title":"Acad Emerg Med."},{"key":"2020110613021280900_ocv070-B71","article-title":"Comparing ICD9-encoded diagnoses and NLP-processed discharge summaries for clinical trials pre-screening: a case study","author":"Li","year":"2008","journal-title":"AMIA Ann Symp Proc."},{"issue":"e2","key":"2020110613021280900_ocv070-B72","first-page":"e306","article-title":"Use of computerized algorithm to identify individuals in need of testing for celiac disease","volume":"20","author":"Ludvigsson","year":"2013","journal-title":"JAMIA."},{"issue":"1","key":"2020110613021280900_ocv070-B73","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/00024665-200301000-00012","article-title":"Modeling nursing care in health level 7 reference information model","volume":"21","author":"Hellenman","year":"2003","journal-title":"Comput Inform Nurs."}],"container-title":["Journal of the American Medical Informatics Association"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jamia\/article-pdf\/22\/6\/1251\/34145876\/ocv070.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jamia\/article-pdf\/22\/6\/1251\/34145876\/ocv070.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T18:54:17Z","timestamp":1604688857000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jamia\/article\/22\/6\/1251\/2357681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,29]]},"references-count":73,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2015,7,29]]},"published-print":{"date-parts":[[2015,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jamia\/ocv070","relation":{},"ISSN":["1527-974X","1067-5027"],"issn-type":[{"value":"1527-974X","type":"electronic"},{"value":"1067-5027","type":"print"}],"subject":[],"published-other":{"date-parts":[[2015,11]]},"published":{"date-parts":[[2015,7,29]]}}}