{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T04:06:32Z","timestamp":1771560392315,"version":"3.50.1"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Objective Increasing the use of generic medications could help control medical costs. However, educational interventions have limited impact on prescriber behavior, and e-prescribing alerts are associated with high override rates and alert fatigue. Our objective was to evaluate the effect of a less intrusive intervention, a redesign of an e-prescribing interface that provides default options intended to \u201cnudge\u201d prescribers towards prescribing generic drugs.<\/jats:p>\n               <jats:p>Methods This retrospective cohort study in an academic ambulatory multispecialty practice assessed the effects of customizing an e-prescribing interface to substitute generic equivalents for brand-name medications during order entry and allow a one-click override to order the brand-name medication.<\/jats:p>\n               <jats:p>Results Among drugs with generic equivalents, the proportion of generic drugs prescribed more than doubled after the interface redesign, rising abruptly from 39.7% to 95.9% (a 56.2% increase; 95% confidence interval, 56.0\u201356.4%; P \u2009&amp;lt;\u2009.001). Before the redesign, generic drug prescribing rates varied by therapeutic class, with rates as low as 8.6% for genitourinary products and 15.7% for neuromuscular drugs. After the redesign, generic drug prescribing rates for all but four therapeutic classes were above 90%: endocrine drugs, neuromuscular drugs, nutritional products, and miscellaneous products.<\/jats:p>\n               <jats:p>Discussion Changing the default option in an e-prescribing interface in an ambulatory care setting was followed by large and sustained increases in the proportion of generic drugs prescribed at the practice.<\/jats:p>\n               <jats:p>Conclusions Default options in health information technology exert a powerful effect on user behavior, an effect that can be leveraged to optimize decision making.<\/jats:p>","DOI":"10.1093\/jamia\/ocv192","type":"journal-article","created":{"date-parts":[[2016,2,18]],"date-time":"2016-02-18T18:21:34Z","timestamp":1455819694000},"page":"891-898","source":"Crossref","is-referenced-by-count":45,"title":["Effects of an e-Prescribing interface redesign on rates of generic drug prescribing: exploiting default options"],"prefix":"10.1093","volume":"23","author":[{"given":"Sameer","family":"Malhotra","sequence":"first","affiliation":[{"name":"Department of Healthcare Policy and Research, Weill Cornell Medical College, New York, NY, USA"},{"name":"Physician Organization, Weill Cornell Medical College, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam D","family":"Cheriff","sequence":"additional","affiliation":[{"name":"Department of Healthcare Policy and Research, Weill Cornell Medical College, New York, NY, USA"},{"name":"Physician Organization, Weill Cornell Medical College, New York, NY, USA"},{"name":"Department of Medicine, Weill Cornell Medical College, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J Travis","family":"Gossey","sequence":"additional","affiliation":[{"name":"Physician Organization, Weill Cornell Medical College, New York, NY, USA"},{"name":"Department of Medicine, Weill Cornell Medical College, New 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