{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T17:12:55Z","timestamp":1783098775755,"version":"3.54.6"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2018,2,10]],"date-time":"2018-02-10T00:00:00Z","timestamp":1518220800000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"European Community\u2019s Horizon 2020 Programme","award":["668353"],"award-info":[{"award-number":["668353"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Clinical pharmacogenomics (PGx) has the potential to make pharmacotherapy safer and more effective by utilizing genetic patient data for drug dosing and selection. However, widespread adoption of PGx depends on its successful integration into routine clinical care through clinical decision support tools, which is often hampered by insufficient or fragmented infrastructures. This paper describes the setup and implementation of a unique multimodal, multilingual clinical decision support intervention consisting of digital, paper-, and mobile-based tools that are deployed across implementation sites in seven European countries participating in the Ubiquitous PGx (U-PGx) project.<\/jats:p>","DOI":"10.1093\/jamia\/ocy005","type":"journal-article","created":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T15:52:50Z","timestamp":1515513170000},"page":"893-898","source":"Crossref","is-referenced-by-count":77,"title":["Implementing pharmacogenomics decision support across seven European countries: The Ubiquitous Pharmacogenomics (U-PGx) project"],"prefix":"10.1093","volume":"25","author":[{"given":"Kathrin","family":"Blagec","sequence":"first","affiliation":[{"name":"Section for Artificial Intelligence and Decision Support; Center for Medical Statistics, Informatics, and Intelligent Systems; Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Koopmann","sequence":"additional","affiliation":[{"name":"bio.logis Genetic Information Management GmbH, Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandy","family":"Crommentuijn \u2013 van Rhenen","sequence":"additional","affiliation":[{"name":"Medicines Information Centre; Royal Dutch Pharmacists Association (KNMP), The Hague, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inge","family":"Holsappel","sequence":"additional","affiliation":[{"name":"Medicines Information Centre; Royal Dutch Pharmacists Association (KNMP), The Hague, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathelijne H","family":"van der Wouden","sequence":"additional","affiliation":[{"name":"Deptartment of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The 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Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Just","sequence":"additional","affiliation":[{"name":"bio.logis Genetic Information Management GmbH, Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse J","family":"Swen","sequence":"additional","affiliation":[{"name":"Deptartment of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henk-Jan","family":"Guchelaar","sequence":"additional","affiliation":[{"name":"Deptartment of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Samwald","sequence":"additional","affiliation":[{"name":"Section for Artificial Intelligence and Decision Support; Center for Medical Statistics, Informatics, and Intelligent Systems; Medical University 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