{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:04:26Z","timestamp":1767827066504,"version":"3.49.0"},"reference-count":56,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T00:00:00Z","timestamp":1556323200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000092","name":"National Library of Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000092","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01LM011966"],"award-info":[{"award-number":["R01LM011966"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The study sought to determine availability and use of structured override reasons for drug-drug interaction (DDI) alerts in electronic health records.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials and Methods<\/jats:title>\n                  <jats:p>We collected data on DDI alerts and override reasons from 10 clinical sites across the United States using a variety of electronic health records. We used a multistage iterative card sort method to categorize the override reasons from all sites and identified best practices.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Our methodology established 177 unique override reasons across the 10 sites. The number of coded override reasons at each site ranged from 3 to 100. Many sites offered override reasons not relevant to DDIs. Twelve categories of override reasons were identified. Three categories accounted for 78% of all overrides: \u201cwill monitor or take precautions,\u201d \u201cnot clinically significant,\u201d and \u201cbenefit outweighs risk.\u201d<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>We found wide variability in override reasons between sites and many opportunities to improve alerts. Some override reasons were irrelevant to DDIs. Many override reasons attested to a future action (eg, decreasing a dose or ordering monitoring tests), which requires an additional step after the alert is overridden, unless the alert is made actionable. Some override reasons deferred to another party, although override reasons often are not visible to other users. Many override reasons stated that the alert was inaccurate, suggesting that specificity of alerts could be improved.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Organizations should improve the options available to providers who choose to override DDI alerts. DDI alerting systems should be actionable and alerts should be tailored to the patient and drug pairs.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jamia\/ocz033","type":"journal-article","created":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T04:22:36Z","timestamp":1551932556000},"page":"934-942","source":"Crossref","is-referenced-by-count":41,"title":["Structured override reasons for drug-drug interaction alerts in electronic health records"],"prefix":"10.1093","volume":"26","author":[{"given":"Adam","family":"Wright","sequence":"first","affiliation":[{"name":"Division of General Internal Medicine and Primary Care, Brigham and Women\u2019s Hospital, Boston, Massachusetts, USA"},{"name":"Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA"},{"name":"Partners eCare, Partners HealthCare, Boston, Massachusetts, USA"}]},{"given":"Dustin S","family":"McEvoy","sequence":"additional","affiliation":[{"name":"Partners eCare, Partners HealthCare, Boston, Massachusetts, USA"}]},{"given":"Skye","family":"Aaron","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine and Primary Care, Brigham and Women\u2019s Hospital, Boston, Massachusetts, USA"}]},{"given":"Allison B","family":"McCoy","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}]},{"given":"Mary G","family":"Amato","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine and Primary Care, Brigham and Women\u2019s Hospital, Boston, Massachusetts, USA"},{"name":"Department of Pharmacy Practice, Massachusetts College of Pharmacy and Health Sciences University, Boston, Massachusetts, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6970-8387","authenticated-orcid":false,"given":"Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Clinical Pharmacogenomics Service, Boston Children\u2019s Hospital, Boston, Massachusetts, USA"}]},{"given":"Angela","family":"Ai","sequence":"additional","affiliation":[{"name":"University of Wisconsin School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, USA"}]},{"given":"James J","family":"Cimino","sequence":"additional","affiliation":[{"name":"Informatics Institute and Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA"}]},{"given":"Bimal R","family":"Desai","sequence":"additional","affiliation":[{"name":"Division of General Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA"}]},{"given":"Robert","family":"El-Kareh","sequence":"additional","affiliation":[{"name":"Department of Medicine, UC San Diego Health, University of California, San Diego, San Diego, California, USA"}]},{"given":"William","family":"Galanter","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4908-6856","authenticated-orcid":false,"given":"Christopher A","family":"Longhurst","sequence":"additional","affiliation":[{"name":"Department of Medicine, UC San Diego Health, University of California, San Diego, San Diego, California, USA"}]},{"given":"Sameer","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Department of Healthcare Policy and Research, Weill Cornell Medicine, New York, New York, USA"}]},{"given":"Ryan P","family":"Radecki","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Northwest Permanente, Portland, Oregon, USA"}]},{"given":"Lipika","family":"Samal","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine and Primary Care, Brigham and Women\u2019s Hospital, Boston, Massachusetts, USA"},{"name":"Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA"}]},{"given":"Richard","family":"Schreiber","sequence":"additional","affiliation":[{"name":"Physician Informatics and Department of Internal Medicine, Geisinger Holy Spirit, Camp Hill, Pennsylvania, USA"}]},{"given":"Eric","family":"Shelov","sequence":"additional","affiliation":[{"name":"Division of General Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA"}]},{"given":"Anwar Mohammad","family":"Sirajuddin","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Memorial Hermann Health System, Houston, Texas, USA"}]},{"given":"Dean F","family":"Sittig","sequence":"additional","affiliation":[{"name":"School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, Texas, USA"}]}],"member":"286","published-online":{"date-parts":[[2019,4,26]]},"reference":[{"issue":"4","key":"2020110613064446700_ocz033-B1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1001\/jama.1997.03540280039031","article-title":"Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality","volume":"277","author":"Classen","year":"1997","journal-title":"JAMA"},{"issue":"24","key":"2020110613064446700_ocz033-B2","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1056\/NEJM197106172842408","article-title":"Preventable drug reactions\u2013causes and cures","volume":"284","author":"Melmon","year":"1971","journal-title":"N Engl J Med"},{"issue":"1","key":"2020110613064446700_ocz033-B3","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1001\/jama.1995.03530010043033","article-title":"Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group","volume":"274","author":"Bates","year":"1995","journal-title":"JAMA"},{"issue":"6","key":"2020110613064446700_ocz033-B4","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/BF02600138","article-title":"Incidence and preventability of adverse drug events in hospitalized adults","volume":"8","author":"Bates","year":"1993","journal-title":"J Gen Intern Med"},{"issue":"4","key":"2020110613064446700_ocz033-B5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BF02600255","article-title":"Relationship between medication errors and adverse drug events","volume":"10","author":"Bates","year":"1995","journal-title":"J Gen Intern Med"},{"issue":"4","key":"2020110613064446700_ocz033-B6","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1001\/jama.1997.03540280050033","article-title":"Factors related to errors in medication prescribing","volume":"277","author":"Lesar","year":"1997","journal-title":"JAMA"},{"issue":"12","key":"2020110613064446700_ocz033-B7","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1001\/archinte.163.12.1409","article-title":"Effects of computerized physician order entry and clinical decision support systems on medication safety: a systematic review","volume":"163","author":"Kaushal","year":"2003","journal-title":"Arch Intern Med"},{"issue":"1","key":"2020110613064446700_ocz033-B8","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1197\/jamia.M2170","article-title":"Medication-related clinical decision support in computerized provider order entry systems: a review","volume":"14","author":"Kuperman","year":"2007","journal-title":"J Am Med Inform Assoc"},{"key":"2020110613064446700_ocz033-B9","doi-asserted-by":"crossref","DOI":"10.1007\/s11606-018-4415-9","article-title":"Reduced effectiveness of interruptive drug-drug interaction alerts after conversion to a commercial electronic health record","author":"Wright","year":"2018","journal-title":"J Gen Intern Med"},{"issue":"2","key":"2020110613064446700_ocz033-B10","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1197\/jamia.M1809","article-title":"Overriding of drug safety alerts in computerized physician order entry","volume":"13","author":"van der Sijs","year":"2006","journal-title":"J Am Med Inform Assoc"},{"issue":"2","key":"2020110613064446700_ocz033-B11","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S1086-5802(16)31243-8","article-title":"Preventable medication errors: identifying and eliminating serious drug interactions","volume":"41","author":"Peterson","year":"2001","journal-title":"J Am Pharm Assoc (Wash)"},{"key":"2020110613064446700_ocz033-B12","article-title":"Evaluation of harm associated with high dose-range clinical decision support overrides in the intensive care unit","author":"Wong","year":"2018","journal-title":"Drug Saf"},{"issue":"2","key":"2020110613064446700_ocz033-B13","first-page":"195","article-title":"Clinical decision support alert appropriateness: a review and proposal for improvement","volume":"14","author":"McCoy","year":"2014","journal-title":"Ochsner J"},{"issue":"3","key":"2020110613064446700_ocz033-B14","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1136\/amiajnl-2011-000185","article-title":"A framework for evaluating the appropriateness of clinical decision support alerts and responses","volume":"19","author":"McCoy","year":"2012","journal-title":"J Am Med Inform Assoc"},{"issue":"2","key":"2020110613064446700_ocz033-B15","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1055\/s-0038-1642608","article-title":"Determining Inappropriate Medication Alerts from \u201cInaccurate Warning\u201d Overrides in the Intensive Care Unit","volume":"09","author":"Rehr","year":"2018","journal-title":"Appl Clin Inform"},{"issue":"12","key":"2020110613064446700_ocz033-B16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0085071","article-title":"Are we heeding the warning signs? Examining providers\u2019 overrides of computerized drug-drug interaction alerts in primary care","volume":"8","author":"Slight","year":"2013","journal-title":"PLoS One"},{"issue":"21","key":"2020110613064446700_ocz033-B17","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1001\/archinte.163.21.2625","article-title":"Physicians' decisions to override computerized drug alerts in primary care","volume":"163","author":"Weingart","year":"2003","journal-title":"Arch Intern Med"},{"issue":"6","key":"2020110613064446700_ocz033-B18","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1056\/NEJMp1006114","article-title":"The \u201cmeaningful use\u201d regulation for electronic health records","volume":"363","author":"Blumenthal","year":"2010","journal-title":"N Engl J Med"},{"issue":"8","key":"2020110613064446700_ocz033-B19","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1056\/NEJMc1213481","article-title":"Early results of the meaningful use program for electronic health records","volume":"368","author":"Wright","year":"2013","journal-title":"N Engl J Med"},{"issue":"3","key":"2020110613064446700_ocz033-B20","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1136\/amiajnl-2012-001089","article-title":"Drug-drug interactions that should be non-interruptive in order to reduce alert fatigue in electronic health records","volume":"20","author":"Phansalkar","year":"2013","journal-title":"J Am Med Inform Assoc"},{"key":"2020110613064446700_ocz033-B21","doi-asserted-by":"crossref","first-page":"19.","DOI":"10.1186\/s13326-015-0018-0","article-title":"Evaluating drug-drug interaction information in NDF-RT and DrugBank","volume":"6","author":"Peters","year":"2015","journal-title":"J Biomed Semantics"},{"issue":"2","key":"2020110613064446700_ocz033-B22","article-title":"Drug-drug interaction alerts: emphasizing the evidence","volume":"5","author":"Hoffman","year":"2012","journal-title":"Saint Louis Univ J Health Law Policy"},{"issue":"4","key":"2020110613064446700_ocz033-B23","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1093\/ajhp\/61.4.380","article-title":"Evaluation of personal digital assistant software for drug interactions","volume":"61","author":"Barrons","year":"2004","journal-title":"Am J Health Syst Pharm"},{"key":"2020110613064446700_ocz033-B24","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.ijmedinf.2017.05.011","article-title":"A systematic review of the effectiveness of interruptive medication prescribing alerts in hospital CPOE systems to change prescriber behavior and improve patient safety","volume":"105","author":"Page","year":"2017","journal-title":"Int J Med Inform"},{"issue":"3","key":"2020110613064446700_ocz033-B25","doi-asserted-by":"crossref","first-page":"866","DOI":"10.4338\/ACI-2017-04-RA-0059","article-title":"Comparison of overridden medication-related clinical decision support in the intensive care unit between a commercial system and a legacy system","volume":"08","author":"Wong","year":"2017","journal-title":"Appl Clin Inform"},{"issue":"2","key":"2020110613064446700_ocz033-B26","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1093\/jamia\/ocw114","article-title":"Variation in high-priority drug-drug interaction alerts across institutions and electronic health records","volume":"24","author":"McEvoy","year":"2017","journal-title":"J Am Med Inform Assoc"},{"issue":"5","key":"2020110613064446700_ocz033-B27","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1136\/amiajnl-2011-000612","article-title":"High-priority drug-drug interactions for use in electronic health records","volume":"19","author":"Phansalkar","year":"2012","journal-title":"J Am Med Inform Assoc"},{"issue":"11","key":"2020110613064446700_ocz033-B28","doi-asserted-by":"crossref","DOI":"10.1093\/jamia\/ocy112","article-title":"Efficacy and unintended consequences of hard-stop alerts in electronic health record systems: a systematic review","volume":"25","author":"Powers","year":"2018","journal-title":"J Am Med Inform Assoc"},{"key":"2020110613064446700_ocz033-B29","first-page":"111","article-title":"Alert override reasons: a failure to communicate","volume":"2008:","author":"Chused","year":"2008","journal-title":"AMIA Annu Symp Proc"},{"key":"2020110613064446700_ocz033-B30","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ijmedinf.2018.08.001","article-title":"Best practices for preventing malfunctions in rule-based clinical decision support alerts and reminders: results of a Delphi study","volume":"118","author":"Wright","year":"2018","journal-title":"Int J Med Inform"},{"key":"2020110613064446700_ocz033-B31","volume-title":"The Accidental Taxonomist","author":"Hedden","year":"2016","edition":"2nd ed"},{"key":"2020110613064446700_ocz033-B32","volume-title":"Structures for Organizing Knowledge: Exploring Taxonomies, Ontologies, and Other Schemas","author":"Abbas","year":"2010"},{"key":"2020110613064446700_ocz033-B33","doi-asserted-by":"crossref","DOI":"10.1016\/0147-1767(85)90062-8","volume-title":"Naturalistic Inquiry","author":"Lincoln","year":"1985"},{"issue":"5","key":"2020110613064446700_ocz033-B34","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1197\/jamia.M2042","article-title":"Types of unintended consequences related to computerized provider order entry","volume":"13","author":"Campbell","year":"2006","journal-title":"J Am Med Inform Assoc"},{"issue":"4","key":"2020110613064446700_ocz033-B35","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1197\/jamia.M2364","article-title":"A description and functional taxonomy of rule-based decision support content at a large integrated delivery network","volume":"14","author":"Wright","year":"2007","journal-title":"J Am Med Inform Assoc"},{"issue":"3","key":"2020110613064446700_ocz033-B36","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1136\/amiajnl-2011-000113","article-title":"Development and evaluation of a comprehensive clinical decision support taxonomy: comparison of front-end tools in commercial and internally developed electronic health record systems","volume":"18","author":"Wright","year":"2011","journal-title":"J Am Med Inform Assoc"},{"key":"2020110613064446700_ocz033-B37","first-page":"158","article-title":"Persistent paper: the myth of \u201cgoing paperless\u201d","volume":"2009","author":"Dykstra","year":"2009","journal-title":"AMIA Annu Symp Proc"},{"issue":"1","key":"2020110613064446700_ocz033-B38","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s11606-008-0857-9","article-title":"Computerized provider order entry adoption: implications for clinical workflow","volume":"24","author":"Campbell","year":"2009","journal-title":"J Gen Intern Med"},{"key":"2020110613064446700_ocz033-B39","doi-asserted-by":"crossref","first-page":"S69","DOI":"10.1016\/j.ijmedinf.2008.07.015","article-title":"The unintended consequences of computerized provider order entry: findings from a mixed methods exploration","volume":"78 (Suppl 1)","author":"Ash","year":"2009","journal-title":"Int J Med Inform"},{"issue":"Pt 1","key":"2020110613064446700_ocz033-B40","first-page":"198","article-title":"Exploring the unintended consequences of computerized physician order entry","volume":"129","author":"Ash","year":"2007","journal-title":"Stud Health Technol Inform"},{"issue":"6","key":"2020110613064446700_ocz033-B41","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/jamia\/ocy003","article-title":"Communication failure: analysis of prescribers' use of an internal free-text field on electronic prescriptions","volume":"25","author":"Ai","year":"2018","journal-title":"J Am Med Inform Assoc"},{"issue":"5","key":"2020110613064446700_ocz033-B42","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1093\/jamia\/ocx106","article-title":"Clinical decision support alert malfunctions: analysis and empirically derived taxonomy","volume":"25","author":"Wright","year":"2018","journal-title":"J Am Med Inform Assoc"},{"issue":"10","key":"2020110613064446700_ocz033-B43","first-page":"573","article-title":"Reasons provided by prescribers when overriding drug-drug interaction alerts","volume":"13","author":"Grizzle","year":"2007","journal-title":"Am J Manag Care"},{"issue":"6","key":"2020110613064446700_ocz033-B44","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/0735-6757(91)90110-6","article-title":"Ciprofloxacin interaction with sodium warfarin: a potentially dangerous side effect","volume":"9","author":"Renzi","year":"1991","journal-title":"Am J Emerg Med"},{"issue":"1","key":"2020110613064446700_ocz033-B45","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s11239-007-0164-z","article-title":"Impact of preemptive warfarin dose reduction on anticoagulation after initiation of trimethoprim-sulfamethoxazole or levofloxacin","volume":"26","author":"Ahmed","year":"2008","journal-title":"J Thromb Thrombolysis"},{"issue":"1","key":"2020110613064446700_ocz033-B46","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.hjdsi.2017.06.004","article-title":"Improving the safety of health information technology requires shared responsibility: It is time we all step up","volume":"6","author":"Sittig","year":"2018","journal-title":"Healthc (Amst)"},{"key":"2020110613064446700_ocz033-B47","first-page":"80","article-title":"Studying the vendor perspective on clinical decision support","volume":"2011","author":"Ash","year":"2011","journal-title":"AMIA Annu Symp Proc"},{"issue":"1","key":"2020110613064446700_ocz033-B48","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1197\/jamia.M2808","article-title":"Tiering drug-drug interaction alerts by severity increases compliance rates","volume":"16","author":"Paterno","year":"2009","journal-title":"J Am Med Inform Assoc"},{"issue":"6","key":"2020110613064446700_ocz033-B49","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1197\/jamia.M1370","article-title":"Ten commandments for effective clinical decision support: making the practice of evidence-based medicine a reality","volume":"10","author":"Bates","year":"2003","journal-title":"J Am Med Inform Assoc"},{"issue":"7494","key":"2020110613064446700_ocz033-B50","doi-asserted-by":"crossref","first-page":"765.","DOI":"10.1136\/bmj.38398.500764.8F","article-title":"Improving clinical practice using clinical decision support systems: a systematic review of trials to identify features critical to success","volume":"330","author":"Kawamoto","year":"2005","journal-title":"BMJ"},{"issue":"2","key":"2020110613064446700_ocz033-B51","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/PTS.0b013e31821d6f6e","article-title":"Critical drug-drug interactions for use in electronic health records systems with computerized physician order entry: review of leading approaches","volume":"7","author":"Classen","year":"2011","journal-title":"J Patient Saf"},{"issue":"1","key":"2020110613064446700_ocz033-B52","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/PTS.0000000000000050","article-title":"Core drug-drug interaction alerts for inclusion in pediatric electronic health records with computerized prescriber order entry","volume":"10","author":"Harper","year":"2014","journal-title":"J Patient Saf"},{"issue":"e1","key":"2020110613064446700_ocz033-B53","doi-asserted-by":"crossref","first-page":"e85","DOI":"10.1136\/amiajnl-2012-001549","article-title":"Relationship between medication event rates and the Leapfrog computerized physician order entry evaluation tool","volume":"20","author":"Leung","year":"2013","journal-title":"J Am Med Inform Assoc"},{"issue":"4","key":"2020110613064446700_ocz033-B54","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1377\/hlthaff.2010.0160","article-title":"Mixed results in the safety performance of computerized physician order entry","volume":"29","author":"Metzger","year":"2010","journal-title":"Health Aff (Millwood)"},{"issue":"2","key":"2020110613064446700_ocz033-B55","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/jamia\/ocw134","article-title":"National trends in safety performance of electronic health record systems in children's hospitals","volume":"24","author":"Chaparro","year":"2017","journal-title":"J Am Med Inform Assoc"},{"issue":"1","key":"2020110613064446700_ocz033-B56","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1093\/jamia\/ocy139","article-title":"Cranky comments: detecting clinical decision support malfunctions through free-text override reasons","volume":"26","author":"Aaron","year":"2019","journal-title":"J Am Med Inform Assoc"}],"container-title":["Journal of the American Medical Informatics Association"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jamia\/article-pdf\/26\/10\/934\/34151769\/ocz033.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jamia\/article-pdf\/26\/10\/934\/34151769\/ocz033.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T19:10:01Z","timestamp":1604689801000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jamia\/article\/26\/10\/934\/5480565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,26]]},"references-count":56,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2019,4,26]]},"published-print":{"date-parts":[[2019,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jamia\/ocz033","relation":{},"ISSN":["1527-974X"],"issn-type":[{"value":"1527-974X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,10]]},"published":{"date-parts":[[2019,4,26]]}}}