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With the core idea of the scientific community developing and curating biological knowledge in pathway models, WikiPathways lowers all barriers for accessing and using its content. Increasingly more content creators, initiatives, projects and tools have started using WikiPathways. Central in this growth and increased use of WikiPathways are the various communities that focus on particular subsets of molecular pathways such as for rare diseases and lipid metabolism. Knowledge from published pathway figures helps prioritize pathway development, using optical character and named entity recognition. We show the growth of WikiPathways over the last three years, highlight the new communities and collaborations of pathway authors and curators, and describe various technologies to connect to external resources and initiatives. The road toward a sustainable, community-driven pathway database goes through integration with other resources such as Wikidata and allowing more use, curation and redistribution of WikiPathways content.<\/jats:p>","DOI":"10.1093\/nar\/gkaa1024","type":"journal-article","created":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T15:21:37Z","timestamp":1603120897000},"page":"D613-D621","source":"Crossref","is-referenced-by-count":778,"title":["WikiPathways: connecting communities"],"prefix":"10.1093","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2230-0840","authenticated-orcid":false,"given":"Marvin","family":"Martens","sequence":"first","affiliation":[{"name":"Department of Bioinformatics - BiGCaT, NUTRIM, Maastricht University, 6229\u00a0ER Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8399-8990","authenticated-orcid":false,"given":"Ammar","family":"Ammar","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics - 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BiGCaT, NUTRIM, Maastricht University, 6229\u00a0ER Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5934-3559","authenticated-orcid":false,"given":"Daniela","family":"Digles","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry\/Pharmacoinformatics Research Group, University of Vienna, 1090 Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1661-6304","authenticated-orcid":false,"given":"Elisson\u00a0N","family":"Lopes","sequence":"additional","affiliation":[{"name":"Instituto de Ciencias Biologicas, Departamento de Bioquimica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, 31270-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7770-620X","authenticated-orcid":false,"given":"Friederike","family":"Ehrhart","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics - BiGCaT, NUTRIM, Maastricht University, 6229\u00a0ER Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2606-3045","authenticated-orcid":false,"given":"Lauren J","family":"Dupuis","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics - BiGCaT, NUTRIM, Maastricht University, 6229\u00a0ER Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9454-4783","authenticated-orcid":false,"given":"Laurent A","family":"Winckers","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics - BiGCaT, NUTRIM, Maastricht University, 6229\u00a0ER Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1224-9690","authenticated-orcid":false,"given":"Susan\u00a0L","family":"Coort","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics - BiGCaT, NUTRIM, Maastricht University, 6229\u00a0ER Maastricht, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7542-0286","authenticated-orcid":false,"given":"Egon L","family":"Willighagen","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics - 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