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While the recent increase in genomic resources holds great promise for a deep understanding of molluscan biology and evolution, access and utilization of these resources still pose a challenge. Here, we present the first comprehensive molluscan genomics database, MolluscDB (http:\/\/mgbase.qnlm.ac), which compiles and integrates current molluscan genomic\/transcriptomic resources and provides convenient tools for multi-level integrative and comparative genomic analyses. MolluscDB enables a systematic view of genomic information from various aspects, such as genome assembly statistics, genome phylogenies, fossil records, gene information, expression profiles, gene families, transcription factors, transposable elements and mitogenome organization information. Moreover, MolluscDB offers valuable customized datasets or resources, such as gene coexpression networks across various developmental stages and adult tissues\/organs, core gene repertoires inferred for major molluscan lineages, and macrosynteny analysis for chromosomal evolution. MolluscDB presents an integrative and comprehensive genomics platform that will allow the molluscan community to cope with ever-growing genomic resources and will expedite new scientific discoveries for understanding molluscan biology and evolution.<\/jats:p>","DOI":"10.1093\/nar\/gkaa918","type":"journal-article","created":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T11:12:38Z","timestamp":1601723558000},"page":"D988-D997","source":"Crossref","is-referenced-by-count":84,"title":["MolluscDB: an integrated functional and evolutionary genomics database for the hyper-diverse animal phylum Mollusca"],"prefix":"10.1093","volume":"49","author":[{"given":"Fuyun","family":"Liu","sequence":"first","affiliation":[{"name":"MOE Key Laboratory of Marine Genetics and Breeding and Sars-Fang Centre, Ocean University of China, Qingdao 266003, China"}]},{"given":"Yuli","family":"Li","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Marine Genetics and Breeding and Sars-Fang Centre, Ocean University of China, Qingdao 266003, China"},{"name":"Laboratory for Marine Biology and Biotechnology, Pilot Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China"}]},{"given":"Hongwei","family":"Yu","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Marine Genetics and Breeding and Sars-Fang Centre, Ocean University of China, Qingdao 266003, China"}]},{"given":"Lingling","family":"Zhang","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Marine Genetics and Breeding and Sars-Fang Centre, Ocean University of China, Qingdao 266003, China"},{"name":"Laboratory for Marine Biology and Biotechnology, Pilot Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China"}]},{"given":"Jingjie","family":"Hu","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Marine Genetics and Breeding and Sars-Fang Centre, Ocean University of China, Qingdao 266003, China"},{"name":"Laboratory of Tropical Marine Germplasm Resources and Breeding Engineering, Sanya Oceanographic Institution, Ocean University of China, Sanya 572000, China"}]},{"given":"Zhenmin","family":"Bao","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Marine Genetics and Breeding and Sars-Fang Centre, Ocean University of China, Qingdao 266003, China"},{"name":"Laboratory of Tropical Marine Germplasm Resources and Breeding Engineering, Sanya Oceanographic Institution, Ocean University of China, Sanya 572000, China"},{"name":"Laboratory for Marine Fisheries Science and Food Production Processes, Pilot Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9571-9864","authenticated-orcid":false,"given":"Shi","family":"Wang","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Marine Genetics and Breeding and Sars-Fang Centre, Ocean University of China, Qingdao 266003, China"},{"name":"Laboratory for Marine Biology and Biotechnology, Pilot Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China"},{"name":"Laboratory of Tropical Marine Germplasm Resources and Breeding Engineering, Sanya Oceanographic Institution, Ocean University of China, Sanya 572000, China"}]}],"member":"286","published-online":{"date-parts":[[2020,10,22]]},"reference":[{"key":"2021010313112245700_B1","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/nature10382","article-title":"Phylogenomics reveals deep molluscan relationships","volume":"477","author":"Kocot","year":"2011","journal-title":"Nature"},{"key":"2021010313112245700_B2","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/brv.12439","article-title":"The evolution of molluscs","volume":"94","author":"Wanninger","year":"2019","journal-title":"Biol. 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Palaeogeography, Palaeoclimatology","volume":"373","author":"Butler","year":"2013","journal-title":"Palaeoecology"},{"key":"2021010313112245700_B5","doi-asserted-by":"crossref","first-page":"e103437","DOI":"10.1371\/journal.pone.0103437","article-title":"Deep-sea octopus (Graneledone boreopacifica) conducts the longest-known egg-brooding period of any animal","volume":"9","author":"Robison","year":"2014","journal-title":"PLoS One"},{"key":"2021010313112245700_B6","volume-title":"FAO yearbook. 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