{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T19:52:24Z","timestamp":1780429944706,"version":"3.54.1"},"reference-count":62,"publisher":"Oxford University Press (OUP)","issue":"D1","funder":[{"DOI":"10.13039\/100000015","name":"U.S. Department of Energy","doi-asserted-by":"publisher","award":["DE-AC02-05CH11231"],"award-info":[{"award-number":["DE-AC02-05CH11231"]}],"id":[{"id":"10.13039\/100000015","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Viruses are integral components of all ecosystems and microbiomes on Earth. Through pervasive infections of their cellular hosts, viruses can reshape microbial community structure and drive global nutrient cycling. Over the past decade, viral sequences identified from genomes and metagenomes have provided an unprecedented view of viral genome diversity in nature. Since 2016, the IMG\/VR database has provided access to the largest collection of viral sequences obtained from (meta)genomes. Here, we present the third version of IMG\/VR, composed of 18 373 cultivated and 2 314 329 uncultivated viral genomes (UViGs), nearly tripling the total number of sequences compared to the previous version. These clustered into 935 362 viral Operational Taxonomic Units (vOTUs), including 188 930 with two or more members. UViGs in IMG\/VR are now reported as single viral contigs, integrated proviruses or genome bins, and are annotated with a new standardized pipeline including genome quality estimation using CheckV, taxonomic classification reflecting the latest ICTV update, and expanded host taxonomy prediction. The new IMG\/VR interface enables users to efficiently browse, search, and select UViGs based on genome features and\/or sequence similarity. IMG\/VR v3 is available at https:\/\/img.jgi.doe.gov\/vr, and the underlying data are available to download at https:\/\/genome.jgi.doe.gov\/portal\/IMG_VR.<\/jats:p>","DOI":"10.1093\/nar\/gkaa946","type":"journal-article","created":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T11:18:49Z","timestamp":1602242329000},"page":"D764-D775","source":"Crossref","is-referenced-by-count":318,"title":["IMG\/VR v3: an integrated ecological and evolutionary framework for interrogating genomes of uncultivated viruses"],"prefix":"10.1093","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5831-5895","authenticated-orcid":false,"given":"Simon","family":"Roux","sequence":"first","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2939-5398","authenticated-orcid":false,"given":"David","family":"P\u00e1ez-Espino","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2026-9798","authenticated-orcid":false,"given":"I-Min A","family":"Chen","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna","family":"Palaniappan","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Ratner","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Chu","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0871-5567","authenticated-orcid":false,"given":"T B K","family":"Reddy","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Nayfach","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederik","family":"Schulz","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Call","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell Y","family":"Neches","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Woyke","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia N","family":"Ivanova","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emiley A","family":"Eloe-Fadrosh","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikos C","family":"Kyrpides","sequence":"additional","affiliation":[{"name":"DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,11,2]]},"reference":[{"key":"2021010313125920100_B1","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/nature19094","article-title":"Uncovering Earth's virome","volume":"536","author":"P\u00e1ez-Espino","year":"2016","journal-title":"Nature"},{"key":"2021010313125920100_B2","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1146\/annurev-virology-101416-041639","article-title":"Viruses in soil ecosystems: an unknown quantity within an unexplored territory","volume":"4","author":"Williamson","year":"2017","journal-title":"Annu. Rev. Virol."},{"key":"2021010313125920100_B3","doi-asserted-by":"crossref","DOI":"10.1038\/nrmicro3404","article-title":"Rising to the challenge: accelerated pace of discovery transforms marine virology","volume":"13","author":"Brum","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"2021010313125920100_B4","doi-asserted-by":"crossref","first-page":"8107","DOI":"10.1128\/JVI.01340-15","article-title":"Dark matter of the biosphere: the amazing world of bacteriophage diversity","volume":"89","author":"Hatfull","year":"2015","journal-title":"J. Virol."},{"key":"2021010313125920100_B5","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1146\/annurev-micro-092412-155633","article-title":"The wonderful world of archaeal viruses","volume":"67","author":"Prangishvili","year":"2013","journal-title":"Annu. Rev. Microbiol."},{"key":"2021010313125920100_B6","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.chom.2019.01.017","article-title":"Bacteriophages of the human gut: the \u201cKnown Unknown\u201d of the microbiome","volume":"25","author":"Shkoporov","year":"2019","journal-title":"Cell Host Microbe"},{"key":"2021010313125920100_B7","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/nrmicro1750","article-title":"Marine viruses\u2013major players in the global ecosystem","volume":"5","author":"Suttle","year":"2007","journal-title":"Nat. Rev. Microbiol."},{"key":"2021010313125920100_B8","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1128\/MMBR.68.3.560-602.2004","article-title":"Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion","volume":"68","author":"Br\u00fcssow","year":"2004","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"2021010313125920100_B9","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/s41564-018-0166-y","article-title":"Phage puppet masters of the marine microbial realm","volume":"3","author":"Breitbart","year":"2018","journal-title":"Nat. Microbiol."},{"key":"2021010313125920100_B10","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/1758-2229.12504","article-title":"Viral ecology comes of age","volume":"9","author":"Sullivan","year":"2017","journal-title":"Environ. Microbiol. Rep."},{"key":"2021010313125920100_B11","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1128\/JVI.03289-14","article-title":"Viromes, not gene markers for studying dsDNA viral communities","volume":"89","author":"Sullivan","year":"2015","journal-title":"J. Virol."},{"key":"2021010313125920100_B12","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1038\/nrmicro1163","article-title":"Viral metagenomics","volume":"3","author":"Edwards","year":"2005","journal-title":"Nat. Rev. Microbiol."},{"key":"2021010313125920100_B13","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3389\/fmicb.2017.01710","article-title":"Virus discovery by metagenomics: the (im)possibilities","volume":"8","author":"Dutilh","year":"2017","journal-title":"Front. Microbiol."},{"key":"2021010313125920100_B14","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/nbt.4306","article-title":"Minimum information about an Uncultivated Virus Genome (MIUViG)","volume":"37","author":"Roux","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"2021010313125920100_B15","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1146\/annurev-virology-092818-015851","article-title":"Expanding the RNA virosphere by unbiased metagenomics","volume":"6","author":"Zhang","year":"2019","journal-title":"Annu. Rev. Virol."},{"key":"2021010313125920100_B16","doi-asserted-by":"crossref","first-page":"e03125","DOI":"10.7554\/eLife.03125","article-title":"Ecology and evolution of viruses infecting uncultivated SUP05 bacteria as revealed by single-cell- and meta- genomics","volume":"3","author":"Roux","year":"2014","journal-title":"Elife"},{"key":"2021010313125920100_B17","doi-asserted-by":"crossref","first-page":"e08490","DOI":"10.7554\/eLife.08490","article-title":"Viral dark matter and virus-host interactions resolved from publicly available microbial genomes","volume":"4","author":"Roux","year":"2015","journal-title":"Elife"},{"key":"2021010313125920100_B18","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1038\/ismej.2015.48","article-title":"Single cell genomics-based analysis of virus-host interactions in marine surface bacterioplankton","volume":"9","author":"Labont\u00e9","year":"2015","journal-title":"ISME J."},{"key":"2021010313125920100_B19","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1038\/s41396-020-0705-4","article-title":"Insights into the dynamics between viruses and their hosts in a hot spring microbial mat","volume":"14","author":"Jarett","year":"2020","journal-title":"ISME J."},{"key":"2021010313125920100_B20","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1038\/nrmicro.2016.177","article-title":"Consensus statement: Virus taxonomy in the age of metagenomics","volume":"15","author":"Simmonds","year":"2017","journal-title":"Nat. Rev. Microbiol."},{"key":"2021010313125920100_B21","doi-asserted-by":"crossref","first-page":"D666","DOI":"10.1093\/nar\/gky901","article-title":"IMG\/M v.5.0: an integrated data management and comparative analysis system for microbial genomes and microbiomes","volume":"47","author":"Chen","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"2021010313125920100_B22","doi-asserted-by":"crossref","first-page":"D457","DOI":"10.1093\/nar\/gkw1030","article-title":"IMG\/VR: a database of cultured and uncultured DNA viruses and retroviruses","volume":"45","author":"P\u00e1ez-Espino","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"2021010313125920100_B23","doi-asserted-by":"crossref","first-page":"D678","DOI":"10.1093\/nar\/gky1127","article-title":"IMG\/VR v.2.0: an integrated data management and analysis system for cultivated and environmental viral genomes","volume":"47","author":"Paez-Espino","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"2021010313125920100_B24","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1038\/s41564-019-0510-x","article-title":"Cryptic inoviruses revealed as pervasive in bacteria and archaea across Earth's biomes","volume":"4","author":"Roux","year":"2019","journal-title":"Nat. Microbiol."},{"key":"2021010313125920100_B25","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1038\/s41586-020-1957-x","article-title":"Giant virus diversity and host interactions through global metagenomics","volume":"578","author":"Schulz","year":"2020","journal-title":"Nature"},{"key":"2021010313125920100_B26","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1186\/s40168-019-0768-5","article-title":"Diversity, evolution, and classification of virophages uncovered through global metagenomics","volume":"7","author":"Paez-Espino","year":"2019","journal-title":"Microbiome"},{"key":"2021010313125920100_B27","doi-asserted-by":"crossref","DOI":"10.1038\/s41587-020-00774-7","article-title":"CheckV: assessing the quality of metagenome-assembled viral genomes","author":"Nayfach","year":"2020","journal-title":"Nat. Biotechnol."},{"key":"2021010313125920100_B28","doi-asserted-by":"crossref","first-page":"e00061-19","DOI":"10.1128\/MMBR.00061-19","article-title":"Global organization and proposed megataxonomy of the viru world","volume":"84","author":"Koonin","year":"2020","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"2021010313125920100_B29","article-title":"A genomic catalogue of Earth's microbiomes","author":"Nayfach","year":"2020","journal-title":"Nat. Biotechnol."},{"key":"2021010313125920100_B30","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1093\/femsre\/fuv048","article-title":"Computational approaches to predict bacteriophage-host relationships","volume":"40","author":"Edwards","year":"2016","journal-title":"FEMS Microbiol. Rev."},{"key":"2021010313125920100_B31","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1038\/nprot.2017.063","article-title":"Nontargeted virus sequence discovery pipeline and virus clustering for metagenomic data","volume":"12","author":"P\u00e1ez-Espino","year":"2017","journal-title":"Nat. Protoc."},{"key":"2021010313125920100_B32","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s40168-017-0283-5","article-title":"VirFinder: a novel k-mer based tool for identifying viral sequences from assembled metagenomic data","volume":"5","author":"Ren","year":"2017","journal-title":"Microbiome"},{"key":"2021010313125920100_B33","doi-asserted-by":"crossref","first-page":"e985","DOI":"10.7717\/peerj.985","article-title":"VirSorter: mining viral signal from microbial genomic data","volume":"3","author":"Roux","year":"2015","journal-title":"PeerJ"},{"key":"2021010313125920100_B34","doi-asserted-by":"crossref","first-page":"D733","DOI":"10.1093\/nar\/gkv1189","article-title":"Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation","volume":"44","author":"O\u2019Leary","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"2021010313125920100_B35","first-page":"D84","article-title":"GenBank","volume":"48","author":"Sayers","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"2021010313125920100_B36","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.cell.2019.03.040","article-title":"Marine DNA viral Macro- and microdiversity from pole to pole","volume":"177","author":"Gregory","year":"2019","journal-title":"Cell"},{"key":"2021010313125920100_B37","doi-asserted-by":"crossref","DOI":"10.1016\/j.chom.2020.08.003","article-title":"The gut virome database reveals age-dependent patterns of virome diversity in the human gut","volume":"28","author":"Gregory","year":"2020","journal-title":"Cell Host Microbe"},{"key":"2021010313125920100_B38","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1186\/1471-2105-10-421","article-title":"BLAST+: architecture and applications","volume":"10","author":"Camacho","year":"2009","journal-title":"BMC Bioinformatics"},{"key":"2021010313125920100_B39","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1038\/ismej.2017.126","article-title":"dRep: a tool for fast and accurate genomic comparisons that enables improved genome recovery from metagenomes through de-replication","volume":"11","author":"Olm","year":"2017","journal-title":"ISME J."},{"key":"2021010313125920100_B40","doi-asserted-by":"crossref","first-page":"806","DOI":"10.3389\/fmicb.2019.00806","article-title":"The promises and pitfalls of machine learning for detecting viruses in aquatic metagenomes","volume":"10","author":"Ponsero","year":"2019","journal-title":"Front. Microbiol."},{"key":"2021010313125920100_B41","doi-asserted-by":"crossref","first-page":"e1002195","DOI":"10.1371\/journal.pcbi.1002195","article-title":"Accelerated profile HMM searches","volume":"7","author":"Eddy","year":"2011","journal-title":"PLoS Comput. Biol."},{"key":"2021010313125920100_B42","doi-asserted-by":"crossref","DOI":"10.1101\/2020.05.15.090266","article-title":"SpacePHARER: sensitive identification of phages from CRISPR spacers in prokaryotic hosts","author":"Zhang","year":"2020"},{"key":"2021010313125920100_B43","doi-asserted-by":"crossref","first-page":"D427","DOI":"10.1093\/nar\/gky995","article-title":"The Pfam protein families database in 2019","volume":"47","author":"El-Gebali","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"2021010313125920100_B44","doi-asserted-by":"crossref","first-page":"e0234636","DOI":"10.1371\/journal.pone.0234636","article-title":"Genomic diversity of bacteriophages infecting Microbacterium spp","volume":"15","author":"Jacobs-Sera","year":"2020","journal-title":"PLoS One"},{"key":"2021010313125920100_B45","doi-asserted-by":"crossref","first-page":"e00992-19","DOI":"10.1128\/AEM.00992-19","article-title":"Potential SUP05-Phage interactions in hydrothermal vent sponges","volume":"85","author":"Zhou","year":"2019","journal-title":"Appl. Environ. Microbiol."},{"key":"2021010313125920100_B46","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s40168-018-0452-1","article-title":"Phages infecting Faecalibacterium prausnitzii belong to novel viral genera that help to decipher intestinal viromes","volume":"6","author":"Cornuault","year":"2018","journal-title":"Microbiome"},{"key":"2021010313125920100_B47","doi-asserted-by":"crossref","first-page":"4498","DOI":"10.1038\/ncomms5498","article-title":"A highly abundant bacteriophage discovered in the unknown sequences of human faecal metagenomes","volume":"5","author":"Dutilh","year":"2014","journal-title":"Nat. Commun."},{"key":"2021010313125920100_B48","doi-asserted-by":"crossref","first-page":"D649","DOI":"10.1093\/nar\/gky977","article-title":"Genomes OnLine database (GOLD) v.7: updates and new features","volume":"47","author":"Mukherjee","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"2021010313125920100_B49","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1111\/j.1462-2920.2010.02270.x","article-title":"A call for standardized classification of metagenome projects","volume":"12","author":"Ivanova","year":"2010","journal-title":"Environ. Microbiol."},{"key":"2021010313125920100_B50","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1021\/acs.est.7b04203","article-title":"Diversity of DNA and RNA viruses in indoor air as assessed via metagenomic sequencing","volume":"52","author":"Rosario","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"2021010313125920100_B51","doi-asserted-by":"crossref","first-page":"194","DOI":"10.3390\/genes10030194","article-title":"Halobacterium salinarum virus ChaoS9, a novel halovirus related to PhiH1 and PhiCh1","volume":"10","author":"Dyall-Smith","year":"2019","journal-title":"Genes (Basel)."},{"key":"2021010313125920100_B52","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1038\/s41396-019-0450-8","article-title":"Diversity patterns of bacteriophages infecting Aggregatibacter and Haemophilus species across clades and niches","volume":"13","author":"Szafra\u0144ski","year":"2019","journal-title":"ISME J."},{"key":"2021010313125920100_B53","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.3389\/fmicb.2019.01951","article-title":"Metagenomic analysis of the diversity of DNA viruses in the surface and deep sea of the south China sea","volume":"10","author":"Liang","year":"2019","journal-title":"Front. Microbiol."},{"key":"2021010313125920100_B54","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.chom.2019.08.019","article-title":"A phage protein aids bacterial symbionts in eukaryote immune evasion","volume":"26","author":"Jahn","year":"2019","journal-title":"Cell Host Microbe"},{"key":"2021010313125920100_B55","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/s41564-019-0612-5","article-title":"A jumbo phage that forms a nucleus-like structure evades CRISPR\u2013Cas DNA targeting but is vulnerable to type III RNA-based immunity","volume":"5","author":"Malone","year":"2020","journal-title":"Nat. Microbiol."},{"key":"2021010313125920100_B56","first-page":"1","article-title":"Long-read viral metagenomics captures abundant and microdiverse viral populations and their niche-defining genomic islands","volume":"2019","author":"Warwick-Dugdale","year":"2019","journal-title":"PeerJ"},{"key":"2021010313125920100_B57","doi-asserted-by":"crossref","first-page":"4126","DOI":"10.1093\/bioinformatics\/btaa490","article-title":"Metaviral SPAdes: assembly of viruses from metagenomic data","volume":"36","author":"Antipov","year":"2020","journal-title":"Bioinformatics"},{"key":"2021010313125920100_B58","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1007\/s00705-020-04577-8","article-title":"Taxonomy of prokaryotic viruses: 2018\u20132019 update from the ICTV Bacterial and Archaeal Viruses Subcommittee","volume":"165","author":"Adriaenssens","year":"2020","journal-title":"Arch. Virol."},{"key":"2021010313125920100_B59","doi-asserted-by":"crossref","first-page":"lqaa044","DOI":"10.1093\/nargab\/lqaa044","article-title":"A network-based integrated framework for predicting virus-host interactions","volume":"2","author":"Wang","year":"2019","journal-title":"NAR Genomics Bioinforma."},{"key":"2021010313125920100_B60","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/ismej.2016.89","article-title":"iVirus: facilitating new insights in viral ecology with software and community data sets imbedded in a cyberinfrastructure","volume":"11","author":"Bolduc","year":"2017","journal-title":"ISME J."},{"key":"2021010313125920100_B61","doi-asserted-by":"crossref","first-page":"D700","DOI":"10.1093\/nar\/gkx1124","article-title":"MVP: a microbe \u2013 phage interaction database","volume":"4","author":"Gao","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"2021010313125920100_B62","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/nbt.4163","article-title":"KBase: the United States Department of Energy systems biology knowledgebase","volume":"36","author":"Arkin","year":"2018","journal-title":"Nat. Biotechnol."}],"container-title":["Nucleic Acids Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/nar\/article-pdf\/49\/D1\/D764\/35364297\/gkaa946.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/nar\/article-pdf\/49\/D1\/D764\/35364297\/gkaa946.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,3]],"date-time":"2021-01-03T18:17:24Z","timestamp":1609697844000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/nar\/article\/49\/D1\/D764\/5952208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,2]]},"references-count":62,"journal-issue":{"issue":"D1","published-online":{"date-parts":[[2020,11,2]]},"published-print":{"date-parts":[[2021,1,8]]}},"URL":"https:\/\/doi.org\/10.1093\/nar\/gkaa946","relation":{},"ISSN":["0305-1048","1362-4962"],"issn-type":[{"value":"0305-1048","type":"print"},{"value":"1362-4962","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,1,8]]},"published":{"date-parts":[[2020,11,2]]}}}