{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T09:34:10Z","timestamp":1767864850421,"version":"3.49.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"D1","license":[{"start":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T00:00:00Z","timestamp":1636416000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["XDB38030400"],"award-info":[{"award-number":["XDB38030400"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["XDA19050302"],"award-info":[{"award-number":["XDA19050302"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004739","name":"Youth Innovation Promotion Association of Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["2019104"],"award-info":[{"award-number":["2019104"]}],"id":[{"id":"10.13039\/501100004739","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32030021"],"award-info":[{"award-number":["32030021"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31871328"],"award-info":[{"award-number":["31871328"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>LncRNAWiki, a knowledgebase of human long non-coding RNAs (lncRNAs), has been rapidly expanded by incorporating more experimentally validated lncRNAs. Since it was built based on MediaWiki as its database system, it fails to manage data in a structured way and is ineffective to support systematic exploration of lncRNAs. Here we present LncRNAWiki 2.0 (https:\/\/ngdc.cncb.ac.cn\/lncrnawiki), which is significantly improved with enhanced database system and curation model. In LncRNAWiki 2.0, all contents are organized in a structured manner powered by MySQL\/Java and curators are able to submit\/edit annotations based on the curation model that includes a wider range of annotation items. Moreover, it is equipped with popular online tools to help users identify lncRNAs with potentially important functions, and provides more user-friendly web interfaces to facilitate data curation, retrieval and visualization. Consequently, LncRNAWiki 2.0 incorporates a total of 2512 lncRNAs and 106 242 associations for disease, function, drug, interacting partner, molecular signature, experimental sample, CRISPR design, etc., thus providing a comprehensive and up-to-date resource of functionally annotated lncRNAs in human.<\/jats:p>","DOI":"10.1093\/nar\/gkab998","type":"journal-article","created":{"date-parts":[[2021,10,9]],"date-time":"2021-10-09T12:18:42Z","timestamp":1633781922000},"page":"D190-D195","source":"Crossref","is-referenced-by-count":33,"title":["LncRNAWiki 2.0: a knowledgebase of human long non-coding RNAs with enhanced curation model and database system"],"prefix":"10.1093","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0419-6130","authenticated-orcid":false,"given":"Lin","family":"Liu","sequence":"first","affiliation":[{"name":"National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing\u00a0100101, China"},{"name":"China National Center for Bioinformation, Beijing\u00a0100101, China"}]},{"given":"Zhao","family":"Li","sequence":"additional","affiliation":[{"name":"National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing\u00a0100101, China"},{"name":"China National Center for Bioinformation, Beijing\u00a0100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing\u00a0100049, China"}]},{"given":"Chang","family":"Liu","sequence":"additional","affiliation":[{"name":"National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing\u00a0100101, China"},{"name":"China National Center for Bioinformation, Beijing\u00a0100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing\u00a0100049, China"}]},{"given":"Dong","family":"Zou","sequence":"additional","affiliation":[{"name":"National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing\u00a0100101, China"},{"name":"China National Center for Bioinformation, Beijing\u00a0100101, China"}]},{"given":"Qianpeng","family":"Li","sequence":"additional","affiliation":[{"name":"National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing\u00a0100101, China"},{"name":"China National Center for Bioinformation, Beijing\u00a0100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing\u00a0100049, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2024-8575","authenticated-orcid":false,"given":"Changrui","family":"Feng","sequence":"additional","affiliation":[{"name":"National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing\u00a0100101, China"},{"name":"China National Center for Bioinformation, Beijing\u00a0100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing\u00a0100049, China"}]},{"given":"Wei","family":"Jing","sequence":"additional","affiliation":[{"name":"National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing\u00a0100101, China"},{"name":"China National Center for Bioinformation, Beijing\u00a0100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing\u00a0100049, China"}]},{"given":"Sicheng","family":"Luo","sequence":"additional","affiliation":[{"name":"National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing\u00a0100101, China"},{"name":"China National Center for Bioinformation, Beijing\u00a0100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing\u00a0100049, China"},{"name":"Sino-Danish College, University of Chinese Academy of Sciences, Beijing\u00a0100049, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6603-5060","authenticated-orcid":false,"given":"Zhang","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing\u00a0100101, China"},{"name":"China National Center for Bioinformation, Beijing\u00a0100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing\u00a0100049, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6390-6289","authenticated-orcid":false,"given":"Lina","family":"Ma","sequence":"additional","affiliation":[{"name":"National Genomics Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing\u00a0100101, China"},{"name":"China National Center for Bioinformation, Beijing\u00a0100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing\u00a0100049, China"}]}],"member":"286","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"key":"2022010507414770400_B1","doi-asserted-by":"crossref","first-page":"D187","DOI":"10.1093\/nar\/gku1167","article-title":"LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs","volume":"43","author":"Ma","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"2022010507414770400_B2","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1101\/gr.132159.111","article-title":"The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression","volume":"22","author":"Derrien","year":"2012","journal-title":"Genome 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Genet."},{"key":"2022010507414770400_B5","doi-asserted-by":"crossref","first-page":"D203","DOI":"10.1093\/nar\/gkv1252","article-title":"NONCODE 2016: an informative and valuable data source of long non-coding RNAs","volume":"44","author":"Zhao","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"2022010507414770400_B6","doi-asserted-by":"crossref","first-page":"D128","DOI":"10.1093\/nar\/gky960","article-title":"LncBook: a curated knowledgebase of human long non-coding RNAs","volume":"47","author":"Ma","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"2022010507414770400_B7","doi-asserted-by":"crossref","first-page":"D962","DOI":"10.1093\/nar\/gkaa850","article-title":"LncExpDB: an expression database of human long non-coding RNAs","volume":"49","author":"Li","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"2022010507414770400_B8","doi-asserted-by":"crossref","first-page":"D18","DOI":"10.1093\/nar\/gkw1060","article-title":"The BIG Data Center: from 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Soc. Trans."},{"key":"2022010507414770400_B30","doi-asserted-by":"crossref","first-page":"D212","DOI":"10.1093\/nar\/gkaa921","article-title":"RNAcentral 2021: secondary structure integration, improved sequence search and new member databases","volume":"49","author":"RNAcentral Consortium","year":"2021","journal-title":"Nucleic Acids Res."}],"container-title":["Nucleic Acids Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/nar\/article-pdf\/50\/D1\/D190\/42058606\/gkab998.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/nar\/article-pdf\/50\/D1\/D190\/42058606\/gkab998.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T08:23:36Z","timestamp":1641371016000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/nar\/article\/50\/D1\/D190\/6423927"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,9]]},"references-count":30,"journal-issue":{"issue":"D1","published-online":{"date-parts":[[2021,11,9]]},"published-print":{"date-parts":[[2022,1,7]]}},"URL":"https:\/\/doi.org\/10.1093\/nar\/gkab998","relation":{},"ISSN":["0305-1048","1362-4962"],"issn-type":[{"value":"0305-1048","type":"print"},{"value":"1362-4962","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,1,7]]},"published":{"date-parts":[[2021,11,9]]}}}