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The MDsrv is a tool that streams MD trajectories and displays them interactively in web browsers without requiring advanced skills, facilitating interactive exploration and collaborative visual analysis. We have now enhanced the MDsrv to further simplify the upload and sharing of MD trajectories and improve their online viewing and analysis. With the new instance, the MDsrv simplifies the creation of sessions, which allows the exchange of MD trajectories with preset representations and perspectives. An important innovation is that the MDsrv can now access and visualize trajectories from remote datasets, which greatly expands its applicability and use, as the data no longer needs to be accessible on a local server. In addition, initial analyses such as sequence or structure alignments, distance measurements, or RMSD calculations have been implemented, which optionally support visual analysis. Finally, based on Mol*, MDsrv now provides faster and more efficient visualization of even large trajectories compared to its predecessor tool NGL.<\/jats:p>","DOI":"10.1093\/nar\/gkac398","type":"journal-article","created":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T20:09:12Z","timestamp":1651781352000},"page":"W483-W489","source":"Crossref","is-referenced-by-count":19,"title":["MDsrv: visual sharing and analysis of molecular dynamics simulations"],"prefix":"10.1093","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4359-2531","authenticated-orcid":false,"given":"Michelle","family":"Kampfrath","sequence":"first","affiliation":[{"name":"Image and Signal Processing Group, Department of Computer Science, Leipzig University , Augustusplatz 10, 04109 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6719-2997","authenticated-orcid":false,"given":"Ren\u00e9","family":"Staritzbichler","sequence":"additional","affiliation":[{"name":"Institute for Medical Physics and Biophysics, Medical Faculty, Leipzig University , H\u00e4rtelstra\u00dfe 16-18, 04107 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9287-8704","authenticated-orcid":false,"given":"Guillermo P\u00e9rez","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Institute of Medical Physics and Biophysics , Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0893-5551","authenticated-orcid":false,"given":"Alexander\u00a0S","family":"Rose","sequence":"additional","affiliation":[{"name":"Mol* Consortium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7551-6245","authenticated-orcid":false,"given":"Johanna K S","family":"Tiemann","sequence":"additional","affiliation":[{"name":"Linderstr\u00f8m-Lang Centre for Protein Science, Department of Biology, University of Copenhagen , Ole Maal\u00f8es Vej 5, DK-2200 Copenhagen N., Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerik","family":"Scheuermann","sequence":"additional","affiliation":[{"name":"Image and Signal Processing Group, Department of Computer Science, Leipzig University , Augustusplatz 10, 04109 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5356-6732","authenticated-orcid":false,"given":"Daniel","family":"Wiegreffe","sequence":"additional","affiliation":[{"name":"Image and Signal Processing Group, Department of Computer Science, Leipzig University , Augustusplatz 10, 04109 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0063-1104","authenticated-orcid":false,"given":"Peter\u00a0W","family":"Hildebrand","sequence":"additional","affiliation":[{"name":"Institute for Medical Physics and Biophysics, Medical Faculty, Leipzig University , H\u00e4rtelstra\u00dfe 16-18, 04107 Leipzig, Germany"},{"name":"Charit\u00e9 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Institute of Medical Physics and Biophysics , Berlin, Germany"},{"name":"Berlin Institute of Health , 10178 Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,5,26]]},"reference":[{"key":"2022070423564806400_B1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1146\/annurev-biophys-042910-155245","article-title":"Biomolecular simulation: a computational microscope for molecular biology","volume":"41","author":"Dror","year":"2012","journal-title":"Annu. 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