{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T13:56:18Z","timestamp":1772718978660,"version":"3.50.1"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"D1","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Third Xinjiang Scientific Expedition Program","award":["2021xjkk0605"],"award-info":[{"award-number":["2021xjkk0605"]}]},{"name":"Third Xinjiang Scientific Expedition Program","award":["2021xjkk0504"],"award-info":[{"award-number":["2021xjkk0504"]}]},{"name":"Foundation of State Key Laboratory for Sheep Genetic Improvement and Healthy Production","award":["2021ZD08"],"award-info":[{"award-number":["2021ZD08"]}]},{"name":"Bingtuan Science and Technology Project","award":["2021CB033"],"award-info":[{"award-number":["2021CB033"]}]},{"name":"Scientific and Technology Innovation Project of the China Academy of Chinese Medical Sciences","award":["C12021A04115"],"award-info":[{"award-number":["C12021A04115"]}]},{"name":"Fundamental Research Funds for the Central Public Welfare Research Institutes","award":["ZZ13-YQ-095"],"award-info":[{"award-number":["ZZ13-YQ-095"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>CRAMdb (a database for composition and roles of animal microbiome) is a comprehensive resource of curated and consistently annotated metagenomes for non-human animals. It focuses on the composition and roles of the microbiome in various animal species. The main goal of the CRAMdb is to facilitate the reuse of animal metagenomic data, and enable cross-host and cross-phenotype comparisons. To this end, we consistently annotated microbiomes (including 16S, 18S, ITS\u00a0and metagenomics sequencing data) of 516 animals from 475 projects spanning 43 phenotype pairs to construct the database that is equipped with 9430 bacteria, 278 archaea, 2216 fungi\u00a0and 458 viruses. CRAMdb provides two main contents: microbiome composition data, illustrating the landscape of the microbiota (bacteria, archaea, fungi, and viruses) in various animal species, and microbiome association data, revealing the relationships between the microbiota and various phenotypes across different animal species. More importantly, users can quickly compare the composition of the microbiota of interest cross-host or body site and the associated taxa that differ between phenotype pairs cross-host or cross-phenotype. CRAMdb is freely available at (http:\/\/www.ehbio.com\/CRAMdb).<\/jats:p>","DOI":"10.1093\/nar\/gkac973","type":"journal-article","created":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T15:50:51Z","timestamp":1667317851000},"page":"D700-D707","source":"Crossref","is-referenced-by-count":10,"title":["CRAMdb: a comprehensive database for composition and roles of microbiome in animals"],"prefix":"10.1093","volume":"51","author":[{"given":"Bingbing","family":"Lei","sequence":"first","affiliation":[{"name":"College of Life Sciences, Shihezi University , Shihezi , Xinjiang \u00a0832003, China"}]},{"given":"Yueren","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shihezi University , Shihezi , Xinjiang \u00a0832003, China"}]},{"given":"Yunjiao","family":"Lei","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shihezi University , Shihezi , Xinjiang \u00a0832003, China"}]},{"given":"Cunyuan","family":"Li","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shihezi University , Shihezi , Xinjiang \u00a0832003, China"},{"name":"Key Laboratory of Ecological Corps for Oasis City and Mountain Basin System, College of Science, Shihezi University , Shihezi , Xinjiang \u00a0832000, China"}]},{"given":"Ping","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science , Xinjiang \u00a0832003, China"}]},{"given":"Limin","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science , Xinjiang \u00a0832003, China"}]},{"given":"Qing","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Ecological Impacts of Hydraulic-Projects and Restoration of Aquatic Ecosystem of Ministry of Water Resources, Institute of Hydroecology Ministry of Water Resources and Chinese Academy of Sciences , Wuhan \u00a0430079, China"}]},{"given":"Xiaoyue","family":"Li","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shihezi University , Shihezi , Xinjiang \u00a0832003, China"}]},{"given":"Fulin","family":"Li","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shihezi University , Shihezi , Xinjiang \u00a0832003, China"}]},{"given":"Chuyang","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shihezi University , Shihezi , Xinjiang \u00a0832003, China"}]},{"given":"Chaowen","family":"Cui","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shihezi University , Shihezi , Xinjiang \u00a0832003, China"}]},{"given":"Tong","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences , Beijing , China"}]},{"given":"Wei","family":"Ni","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shihezi University , Shihezi , Xinjiang \u00a0832003, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8849-265X","authenticated-orcid":false,"given":"Shengwei","family":"Hu","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Shihezi University , Shihezi , Xinjiang \u00a0832003, China"},{"name":"State Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science , Xinjiang \u00a0832003, China"}]}],"member":"286","published-online":{"date-parts":[[2022,11,1]]},"reference":[{"key":"2023010804340337800_B1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s41579-020-0433-9","article-title":"Gut microbiota in human metabolic health and disease","volume":"19","author":"Fan","year":"2021","journal-title":"Nat. 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