{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T13:46:49Z","timestamp":1762177609691,"version":"3.37.3"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"W1","license":[{"start":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T00:00:00Z","timestamp":1684713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Polish National Science Center","award":["2014\/12\/W\/NZ2\/00466"],"award-info":[{"award-number":["2014\/12\/W\/NZ2\/00466"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Archeogenomics is a rapidly growing interdisciplinary research field driven by the development of techniques that enable the acquisition and analysis of ancient DNA (aDNA). Recent advances in aDNA studies have contributed significantly to increasing our understanding of the natural history of humans. One of the most significant challenges facing archeogenomics is the integration of highly heterogeneous genomic, archeological, and anthropological data and their comprehensive analysis, considering changes that occur in time and space. Only this complex approach can explain the relationship between past populations in the context of migration or cultural development. To address these challenges, we developed a Human AGEs web server. It focuses on creating comprehensive spatiotemporal visualizations of genomic, archeogenomic, and archeological information, which can be provided by the user or loaded from a graph database. The interactive map application at the center of Human AGEs can display multiple layers of data in various forms, such as bubble charts, pie charts, heatmaps, or tag clouds. These visualizations can be modified using various clustering, filtering, and styling options, and the map state can be exported to a high-resolution image or saved as a session file for later use. Human AGEs, along with their tutorial, are accessible at https:\/\/archeogenomics.eu\/.<\/jats:p>","DOI":"10.1093\/nar\/gkad428","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T19:33:06Z","timestamp":1684783986000},"page":"W269-W273","source":"Crossref","is-referenced-by-count":1,"title":["Human AGEs: an interactive spatio-temporal visualization and database of human archeogenomics"],"prefix":"10.1093","volume":"51","author":[{"given":"Lukasz","family":"Ciecierski","sequence":"first","affiliation":[{"name":"Institute of Bioorganic Chemistry, Polish Academy of Sciences , Poznan , Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ireneusz","family":"Stolarek","sequence":"additional","affiliation":[{"name":"Institute of Bioorganic Chemistry, Polish Academy of Sciences , Poznan , Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6392-0192","authenticated-orcid":false,"given":"Marek","family":"Figlerowicz","sequence":"additional","affiliation":[{"name":"Institute of Bioorganic Chemistry, Polish Academy of Sciences , Poznan , Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,5,22]]},"reference":[{"key":"2023070505010806600_B1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.fsigen.2007.01.018","article-title":"EMPOP\u2013a forensic mtDNA database","volume":"1","author":"Parson","year":"2007","journal-title":"Forensic Sci. Int. Genet."},{"key":"2023070505010806600_B2","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1038\/s41598-018-20705-6","article-title":"A mosaic genetic structure of the human population living in the South Baltic region during the Iron Age","volume":"8","author":"Stolarek","year":"2018","journal-title":"Sci. Rep."},{"key":"2023070505010806600_B3","doi-asserted-by":"crossref","first-page":"6737","DOI":"10.1038\/s41598-019-43183-w","article-title":"Goth migration induced changes in the matrilineal genetic structure of the central-east European population","volume":"9","author":"Stolarek","year":"2019","journal-title":"Sci. Rep."},{"key":"2023070505010806600_B4","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/s41586-022-05247-2","article-title":"The Anglo-Saxon migration and the formation of the early English gene pool","volume":"610","author":"Gretzinger","year":"2022","journal-title":"Nature"},{"key":"2023070505010806600_B5","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/nature17993","article-title":"The genetic history of Ice Age Europe","volume":"534","author":"Fu","year":"2016","journal-title":"Nature"},{"key":"2023070505010806600_B6","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nature14317","article-title":"Massive migration from the steppe was a source for Indo-European languages in Europe","volume":"522","author":"Haak","year":"2015","journal-title":"Nature"},{"key":"2023070505010806600_B7","doi-asserted-by":"crossref","first-page":"D29","DOI":"10.1093\/nar\/gky843","article-title":"AmtDB: a database of ancient human mitochondrial genomes","volume":"47","author":"Ehler","year":"2019","journal-title":"Nucleic Acids Res."}],"container-title":["Nucleic Acids Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/nar\/article-pdf\/51\/W1\/W269\/50736829\/gkad428.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/nar\/article-pdf\/51\/W1\/W269\/50736829\/gkad428.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T10:49:20Z","timestamp":1688554160000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/nar\/article\/51\/W1\/W269\/7175335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,22]]},"references-count":7,"journal-issue":{"issue":"W1","published-online":{"date-parts":[[2023,5,22]]},"published-print":{"date-parts":[[2023,7,5]]}},"URL":"https:\/\/doi.org\/10.1093\/nar\/gkad428","relation":{},"ISSN":["0305-1048","1362-4962"],"issn-type":[{"type":"print","value":"0305-1048"},{"type":"electronic","value":"1362-4962"}],"subject":[],"published-other":{"date-parts":[[2023,7,5]]},"published":{"date-parts":[[2023,5,22]]}}}