{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T22:27:43Z","timestamp":1774909663302,"version":"3.50.1"},"reference-count":20,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T00:00:00Z","timestamp":1571788800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000051","name":"National Human Genome Research Institute","doi-asserted-by":"publisher","award":["U24 HG002223"],"award-info":[{"award-number":["U24 HG002223"]}],"id":[{"id":"10.13039\/100000051","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/S000453\/1"],"award-info":[{"award-number":["MR\/S000453\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BB\/P024602\/1"],"award-info":[{"award-number":["BB\/P024602\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>WormBase (https:\/\/wormbase.org\/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary facets: curation, user interface and architecture. In this update, we describe progress in each of these three areas. In particular, we discuss the status of literature curation and recently added data, detail new features of the web interface and options for users wishing to conduct data mining workflows, and discuss our efforts to build a robust and scalable architecture by leveraging commercial cloud offerings. We conclude with a description of WormBase's role as a founding member of the nascent Alliance of Genome Resources.<\/jats:p>","DOI":"10.1093\/nar\/gkz920","type":"journal-article","created":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T04:17:03Z","timestamp":1570508223000},"source":"Crossref","is-referenced-by-count":132,"title":["WormBase: a modern Model Organism Information Resource"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3406-163X","authenticated-orcid":false,"given":"Todd W","family":"Harris","sequence":"first","affiliation":[{"name":"Informatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada"}]},{"given":"Valerio","family":"Arnaboldi","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Scott","family":"Cain","sequence":"additional","affiliation":[{"name":"Informatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada"}]},{"given":"Juancarlos","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Wen J","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Jaehyoung","family":"Cho","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Paul","family":"Davis","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"}]},{"given":"Sibyl","family":"Gao","sequence":"additional","affiliation":[{"name":"Informatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada"}]},{"given":"Christian A","family":"Grove","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Ranjana","family":"Kishore","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Raymond Y N","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Hans-Michael","family":"Muller","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Cecilia","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Paulo","family":"Nuin","sequence":"additional","affiliation":[{"name":"Informatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada"}]},{"given":"Michael","family":"Paulini","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"}]},{"given":"Daniela","family":"Raciti","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Faye H","family":"Rodgers","sequence":"additional","affiliation":[{"name":"Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6140-6723","authenticated-orcid":false,"given":"Matthew","family":"Russell","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"}]},{"given":"Gary","family":"Schindelman","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Kimberly V","family":"Auken","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Qinghua","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Gary","family":"Williams","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"}]},{"given":"Adam J","family":"Wright","sequence":"additional","affiliation":[{"name":"Informatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada"}]},{"given":"Karen","family":"Yook","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]},{"given":"Kevin L","family":"Howe","sequence":"additional","affiliation":[{"name":"European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK"}]},{"given":"Tim","family":"Schedl","sequence":"additional","affiliation":[{"name":"Department of Genetics, Washington University School of Medicine, St Louis, MO 63110, USA"}]},{"given":"Lincoln","family":"Stein","sequence":"additional","affiliation":[{"name":"Informatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada"}]},{"given":"Paul W","family":"Sternberg","sequence":"additional","affiliation":[{"name":"Division of Biology and Biological Engineering 156\u201329, California Institute of Technology, Pasadena, CA 91125, USA"}]}],"member":"286","published-online":{"date-parts":[[2019,10,23]]},"reference":[{"key":"2019102305091735000_B1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1093\/nar\/29.1.82","article-title":"WormBase: network access to the genome and biology of Caenorhabditis elegans","volume":"29","author":"Stein","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"2019102305091735000_B2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/nar\/gkg053","article-title":"WormBase: a cross-species database for comparative 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