{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T13:41:43Z","timestamp":1790343703355,"version":"4.1.0"},"reference-count":81,"publisher":"China Science Publishing & Media Ltd.","issue":"8","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Cultivation Fund of Zhejiang University of Technology for Excellent Doctoral Dissertation"},{"name":"Program for Changjiang Scholars and Innovative Research Team in University","award":["IRT17R97"],"award-info":[{"award-number":["IRT17R97"]}]},{"name":"National Key R&D Program of China","award":["2017YFD0200503"],"award-info":[{"award-number":["2017YFD0200503"]}]}],"content-domain":{"domain":["engine.scichina.com"],"crossmark-restriction":false},"short-container-title":["ABBS"],"published-print":{"date-parts":[[2020,7,1]]},"DOI":"10.1093\/abbs\/gmaa049","type":"journal-article","created":{"date-parts":[[2020,4,23]],"date-time":"2020-04-23T07:07:48Z","timestamp":1587625668000},"page":"821-831","update-policy":"https:\/\/doi.org\/10.1360\/scp-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["<bold> <roman>β<\/roman> <\/bold>-Cypermethrin promotes the adipogenesis of 3T3-L1 cells via inducing autophagy and shaping an adipogenesis-friendly microenvironment"],"prefix":"10.3724","volume":"52","author":[{"given":"Bingnan","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xini","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zimeng","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbo","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caiyun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanxiang","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengwei","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2026","published-online":{"date-parts":[[2020,7,7]]},"reference":[{"key":"null","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.jhazmat.2016.10.056","volume":"324","author":"Li H","year":"2017","unstructured":"Li H, Cheng F, Wei Y, Lydy MJ, You J. Global occurrence of pyrethroid insecticides in sediment and the associated toxicological effects on benthic invertebrates: an overview. J Hazard Mater, 2017, 324: 258-271.","journal-title":"J Hazard Mater"},{"key":"null","doi-asserted-by":"crossref","first-page":"17261","DOI":"10.1007\/s11356-019-05013-4","volume":"26","author":"Li WG","year":"2019","unstructured":"Li WG, Huang DY, Chen D, Wang C, Wei GL. Temporal-spatial distribution of synthetic pyrethroids in overlying water and surface sediments in Guangzhou waterways: potential input mechanisms and ecological risk to aquatic systems. Environ Sci Pollut Res Int, 2019, 26: 17261-17276.","journal-title":"Environ Sci Pollut Res Int"},{"key":"null","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.chemosphere.2017.03.138","volume":"180","author":"Han Y","year":"2017","unstructured":"Han Y, Mo R, Yuan X, Zhong D, Tang F, Ye C, Liu Y. Pesticide residues in nut-planted soils of China and their relationship between nut\/soil. Chemosphere, 2017, 180: 42-47.","journal-title":"Chemosphere"},{"key":"null","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/s41370-018-0065-6","volume":"29","author":"Zhou J","year":"2019","unstructured":"Zhou J, Mainelis G, Weisel CP. Pyrethroid levels in toddlers' breathing zone following a simulated indoor pesticide spray. J Expo Sci Environ Epidemiol, 2019, 29: 389-396.","journal-title":"J Expo Sci Environ Epidemiol"},{"key":"null","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1007\/s11356-017-0015-1","volume":"25","author":"Feng X","year":"2018","unstructured":"Feng X, Pan L, Wang C, Zhang H. Residue analysis and risk assessment of pyrethrins in open field and greenhouse turnips. Environ Sci Pollut Res, 2018, 25: 877-886.","journal-title":"Environ Sci Pollut Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"22584","DOI":"10.1007\/s11356-018-1963-9","volume":"25","author":"Riaz G","year":"2018","unstructured":"Riaz G, Tabinda AB, Kashif M, Yasar A, Mahmood A, Rasheed R, Khan MI. Monitoring and spatiotemporal variations of pyrethroid insecticides in surface water, sediment, and fish of the river Chenab Pakistan. Environ Sci Pollut Res, 2018, 25: 22584-22597.","journal-title":"Environ Sci Pollut Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.3109\/10715762.2010.512041","volume":"44","author":"Tiwari MN","year":"2010","unstructured":"Tiwari MN, Singh AK, Ahmad I, Upadhyay G, Singh D, Patel DK, Singh C. Effects of cypermethrin on monoamine transporters, xenobiotic metabolizing enzymes and lipid peroxidation in the rat nigrostriatal system. Free Radic Res, 2010, 44: 1416-1424.","journal-title":"Free Radic Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.neuro.2016.05.005","volume":"60","author":"Johnstone AFM","year":"2017","unstructured":"Johnstone AFM, Strickland JD, Crofton KM, Gennings C, Shafer TJ. Effects of an environmentally-relevant mixture of pyrethroid insecticides on spontaneous activity in primary cortical networks on microelectrode arrays. Neurotoxicology, 2017, 60: 234-239.","journal-title":"Neurotoxicology"},{"key":"null","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1093\/abbs\/gmx111","volume":"49","author":"Wang X","year":"2017","unstructured":"Wang X, He B, Kong B, Wei L, Wang R, Zhou C, Shao Y. \u03b2-Cypermethrin and its metabolite 3-phenoxybenzoic acid exhibit immunotoxicity in murine macrophages. Acta Biochim Biophys Sin, 2017, 49: 1083-1091.","journal-title":"Acta Biochim Biophys Sin"},{"key":"null","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1093\/abbs\/gmy068","volume":"50","author":"He B","year":"2018","unstructured":"He B, Wang X, Wei L, Kong B, Jin Y, Xie X, Fu Z. \u03b2-Cypermethrin and its metabolite 3-phenoxybenzoic acid induce cytotoxicity and block granulocytic cell differentiation in HL-60 cells. Acta Biochim Biophys Sin, 2018, 50: 740-747.","journal-title":"Acta Biochim Biophys Sin"},{"key":"null","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.toxlet.2014.01.006","volume":"225","author":"Jin Y","year":"2014","unstructured":"Jin Y, Lin X, Miao W, Wu T, Shen H, Chen S, Li Y. Chronic exposure of mice to environmental endocrine-disrupting chemicals disturbs their energy metabolism. Toxicol Lett, 2014, 225: 392-400.","journal-title":"Toxicol Lett"},{"key":"null","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1093\/toxsci\/kfs245","volume":"130","author":"Starr JM","year":"2012","unstructured":"Starr JM, Scollon EJ, Hughes MF, Ross DG, Graham SE, Crofton KM, Wolansky MJ. Environmentally relevant mixtures in cumulative assessments: an acute study of toxicokinetics and effects on motor activity in rats exposed to a mixture of pyrethroids. Toxicol Lett, 2012, 130: 309-318.","journal-title":"Toxicol Lett"},{"key":"null","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1093\/toxsci\/kfm277","volume":"101","author":"Kim KB","year":"2008","unstructured":"Kim KB, Anand SS, Kim HJ, White CA, Bruckner JV. Toxicokinetics and tissue distribution of deltamethrin in adult Sprague-Dawley rats. Toxicol Lett, 2008, 101: 197-205.","journal-title":"Toxicol Lett"},{"key":"null","doi-asserted-by":"crossref","first-page":"5012","DOI":"10.1038\/s41598-017-04135-4","volume":"7","author":"He Y","year":"2017","unstructured":"He Y, Pan A, Wang Y, Yang Y, Xu J, Zhang Y, Liu D. Prevalence of overweight and obesity in 15.8 million men aged 15-49 years in rural China from 2010 to 2014. Sci Rep, 2017, 7:","journal-title":"Sci Rep"},{"key":"null","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1007\/s13679-018-0317-8","volume":"7","author":"Inoue Y","year":"2018","unstructured":"Inoue Y, Qin B, Poti J, Sokol R, Gordon-Larsen P. Epidemiology of obesity in adults: latest trends. Curr Obes Rep, 2018, 7: 276-288.","journal-title":"Curr Obes Rep"},{"key":"null","doi-asserted-by":"crossref","first-page":"3469","DOI":"10.1007\/s00204-017-2071-1","volume":"91","author":"Muscogiuri G","year":"2017","unstructured":"Muscogiuri G, Barrea L, Laudisio D, Savastano S, Colao A. Obesogenic endocrine disruptors and obesity: myths and truths. Arch Toxicol, 2017, 91: 3469-3475.","journal-title":"Arch Toxicol"},{"key":"null","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s13679-017-0240-4","volume":"6","author":"Darbre PD","year":"2017","unstructured":"Darbre PD. Endocrine disruptors and obesity. Curr Obes Rep, 2017, 6: 18-27.","journal-title":"Curr Obes Rep"},{"key":"null","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.envres.2019.02.037","volume":"172","author":"Lee KS","year":"2019","unstructured":"Lee KS, Lee YA, Lee YJ, Shin CH, Lim YH, Hong YC. The relationship of urinary 3-phenoxybenzoic acid concentrations in utero and during childhood with adiposity in 4-year-old children. Environ Res, 2019, 172: 446-453.","journal-title":"Environ Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.envres.2018.12.043","volume":"172","author":"Park J","year":"2018","unstructured":"Park J, Park SK, Choi YH. Environmental pyrethroid exposure and diabetes in U.S. adults. Environ Res, 2018, 172: 399-407.","journal-title":"Environ Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.fct.2017.11.047","volume":"111","author":"Xiao X","year":"2018","unstructured":"Xiao X, Sun Q, Kim Y, Yang S-H, Qi W, Kim D, Yoon KS. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL\/6J mice. Food Chem Toxicol, 2018, 111: 405-416.","journal-title":"Food Chem Toxicol"},{"key":"null","doi-asserted-by":"crossref","first-page":"14048","DOI":"10.1021\/acs.jafc.9b06727","volume":"67","author":"Wei C","year":"2019","unstructured":"Wei C, Wang X, Yao X, Xi F, He Y, Xu Y, Ma L. Bifenthrin induces fat deposition by improving fatty acid uptake and inhibiting lipolysis in mice. J Agric Food Chem, 2019, 67: 14048-14055.","journal-title":"J Agric Food Chem"},{"key":"null","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.fct.2017.01.015","volume":"101","author":"Shen P","year":"2017","unstructured":"Shen P, Hsieh TH, Yue Y, Sun Q, Clark JM, Park Y. Deltamethrin increases the fat accumulation in 3T3-L1 adipocytes and Caenorhabditis elegans. Food Chem Toxicol, 2017, 101: 149-156.","journal-title":"Food Chem Toxicol"},{"key":"null","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s12015-017-9774-9","volume":"14","author":"Sarantopoulos CN","year":"2018","unstructured":"Sarantopoulos CN, Banyard DA, Ziegler ME, Sun B, Shaterian A, Widgerow AD. Elucidating the preadipocyte and its role in adipocyte formation: a comprehensive review. Stem Cell Rev, 2018, 14: 27-42.","journal-title":"Stem Cell Rev"},{"key":"null","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.fct.2017.08.049","volume":"109","author":"Xiao X","year":"2017","unstructured":"Xiao X, Qi W, Clark JM, Park Y. Permethrin potentiates adipogenesis via intracellular calcium and endoplasmic reticulum stress-mediated mechanisms in 3T3-L1 adipocytes. Food Chem Toxicol, 2017, 109: 123-129.","journal-title":"Food Chem Toxicol"},{"key":"null","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/jbt.21580","volume":"28","author":"Kim J","year":"2014","unstructured":"Kim J, Park Y, Yoon KS, Clark JM, Park Y. Permethrin alters adipogenesis in 3T3-L1 adipocytes and causes insulin resistance in C2C12 myotubes. J Biochem Mol Toxic, 2014, 28: 418-424.","journal-title":"J Biochem Mol Toxic"},{"key":"null","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.4161\/auto.5.8.9991","volume":"5","author":"Baerga R","year":"2009","unstructured":"Baerga R, Zhang Y, Chen P-H, Goldman S, Jin SV. Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice. Autophagy, 2009, 5: 1118-1130.","journal-title":"Autophagy"},{"key":"null","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.tox.2017.11.010","volume":"393","author":"Luz AL","year":"2018","unstructured":"Luz AL, Kassotis CD, Stapleton HM, Meyer JN. The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPAR\u03b3 activation, in 3T3-L1 cells. Toxicology, 2018, 393: 150-159.","journal-title":"Toxicology"},{"key":"null","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0014-5793(03)00862-7","volume":"550","author":"Carriere A","year":"2003","unstructured":"Carriere A, Fernandez Y, Rigoulet M, Penicaud L, Casteilla L. Inhibition of preadipocyte proliferation by mitochondrial reactive oxygen species. FEBS Lett, 2003, 550: 163-167.","journal-title":"FEBS Lett"},{"key":"null","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1016\/j.biocel.2013.09.011","volume":"45","author":"He Q","year":"2013","unstructured":"He Q, Wang M, Petucci C, Gardell SJ, Han X. Rotenone induces reductive stress and triacylglycerol deposition in C2C12 cells. Int J Biochem Cell Biol, 2013, 45: 2749-2755.","journal-title":"Int J Biochem Cell Biol"},{"key":"null","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1161\/CIRCRESAHA.115.306885","volume":"118","author":"Fuster JJ","year":"2016","unstructured":"Fuster JJ, Ouchi N, Gokce N, Walsh K. Obesity-induced changes in adipose tissue microenvironment and their impact on cardiovascular disease. Circ Res, 2016, 118: 1786-1807.","journal-title":"Circ Res"},{"key":"null","first-page":"1151","volume":"7","author":"Lee MJ","year":"2017","unstructured":"Lee MJ. Hormonal regulation of Adipogenesis. Clin Sci, 2017, 7: 1151-1195.","journal-title":"Clin Sci"},{"key":"null","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1042\/CS20180890","volume":"133","author":"Lorente-Cebrian S","year":"2019","unstructured":"Lorente-Cebrian S, Gonzalez-Muniesa P, Milagro FI, Martinez JA. MicroRNAs and other non-coding RNAs in adipose tissue and obesity: emerging roles as biomarkers and therapeutic targets. Clin Sci, 2019, 133: 23-40.","journal-title":"Clin Sci"},{"key":"null","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.envpol.2019.04.044","volume":"250","author":"He B","year":"2019","unstructured":"He B, Wang X, Zhu J, Kong B, Wei L, Jin Y, Fu Z. Autophagy protects murine macrophages from beta-cypermethrin-induced mitochondrial dysfunction and cytotoxicity via the reduction of oxidation stress. Environ Pollut, 2019, 250: 416-425.","journal-title":"Environ Pollut"},{"key":"null","doi-asserted-by":"crossref","first-page":"885","DOI":"10.3390\/ijms17060885","volume":"17","author":"Huang F","year":"2016","unstructured":"Huang F, Liu Q, Xie S, Xu J, Huang B, Wu Y, Xia D. Cypermethrin induces macrophages death through cell cycle arrest and oxidative stress-mediated JNK\/ERK signaling regulated apoptosis. Int J Mol Sci, 2016, 17:","journal-title":"Int J Mol Sci"},{"key":"null","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1093\/toxsci\/kfy039","volume":"163","author":"Huang F","year":"2018","unstructured":"Huang F, Chen Z, Chen H, Lu W, Xie S, Meng QH, Wu Y. Cypermethrin promotes lung cancer metastasis via modulation of macrophage polarization by targeting MicroRNA-155\/Bcl6. Toxicol Sci, 2018, 163: 454-465.","journal-title":"Toxicol Sci"},{"key":"null","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.cmet.2007.11.002","volume":"7","author":"Eguchi J","year":"2008","unstructured":"Eguchi J, Yan QW, Schones DE, Kamal M, Hsu CH, Zhang MQ, Crawford GE. Interferon regulatory factors are transcriptional regulators of adipogenesis. Cell Metab, 2008, 7: 86-94.","journal-title":"Cell Metab"},{"key":"null","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.3390\/nu10101383","volume":"10","author":"Song Z","year":"2018","unstructured":"Song Z, Xiaoli AM, Yang F. Regulation and metabolic significance of de novo lipogenesis in adipose tissues. Nutrients, 2018, 10:","journal-title":"Nutrients"},{"key":"null","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/j.chemosphere.2016.11.121","volume":"168","author":"Wang X","year":"2017","unstructured":"Wang X, Gao X, He B, Jin Y, Fu Z. Cis-bifenthrin causes immunotoxicity in murine macrophages. Chemosphere, 2017, 168: 1375-1382.","journal-title":"Chemosphere"},{"key":"null","doi-asserted-by":"crossref","first-page":"e454","DOI":"10.1038\/emm.2017.288","volume":"50","author":"Poel D","year":"2018","unstructured":"Poel D, Buffart TE, Oosterling-Jansen J, Verheul HMW, Voortman J. Evaluation of several methodological challenges in circulating miRNA qPCR studies in patients with head and neck cancer. Exp Mol Med, 2018, 50:","journal-title":"Exp Mol Med"},{"key":"null","doi-asserted-by":"crossref","first-page":"e89237","DOI":"10.1371\/journal.pone.0089237","volume":"9","author":"Roberts TC","year":"2014","unstructured":"Roberts TC, Coenen-Stass AML, Wood MJA. Assessment of RT-qPCR normalization strategies for accurate quantification of extracellular microRNAs in murine serum. PLoS One, 2014, 9: e89237-e89237.","journal-title":"PLoS One"},{"key":"null","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.cbpc.2018.12.004","volume":"217","author":"Wang X","year":"2019","unstructured":"Wang X, Wei L, Wang Y, He B, Kong B, Zhu J, Jin Y. Evaluation of development, locomotor behavior, oxidative stress, immune responses and apoptosis in developing zebrafish (Danio rerio) exposed to TBECH (tetrabromoethylcyclohexane). Comp Biochem Physiol C Toxicol Pharmacol, 2019, 217: 106-113.","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"null","doi-asserted-by":"crossref","first-page":"24230","DOI":"10.1007\/s11356-018-2503-3","volume":"25","author":"Yang Y","year":"2018","unstructured":"Yang Y, Liu W, Wang J, Zhang Y, Xu W, Tao L. The different effects of natural pyrethrins and beta-cypermethrin on human hepatocyte QSG7701 cells by ROS-mediated oxidative damage. Environ Sci Pollut R, 2018, 25: 24230-24240.","journal-title":"Environ Sci Pollut R"},{"key":"null","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ecoenv.2019.03.109","volume":"177","author":"Wang Q","year":"2019","unstructured":"Wang Q, Wang HX, Shen JY, Zhang R, Hong JW, Li Z, Chen G. The anti-androgenic effects of cypermethrin mediated by non-classical testosterone pathway activation of mitogen-activated protein kinase cascade in mouse Sertoli cells. Ecotoxicol Environ Saf, 2019, 177: 58-65.","journal-title":"Ecotoxicol Environ Saf"},{"key":"null","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.ecoenv.2014.12.032","volume":"113","author":"Wei K","year":"2015","unstructured":"Wei K, Yang J. Oxidative damage induced by copper and beta-cypermethrin in gill of the freshwater crayfish Procambarus clarkii. Ecotoxicol Environ Saf, 2015, 113: 446-453.","journal-title":"Ecotoxicol Environ Saf"},{"key":"null","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.envres.2016.05.003","volume":"149","author":"Wang X","year":"2016","unstructured":"Wang X, Mart\u00ednez M-A, Dai M, Chen D, Ares I, Romero A, Castellano V. Permethrin-induced oxidative stress and toxicity and metabolism. A review. Environ Res, 2016, 149: 86-104.","journal-title":"Environ Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.cmet.2016.09.017","volume":"25","author":"Kauppila TES","year":"2017","unstructured":"Kauppila TES, Kauppila JHK, Larsson NG. Mammalian mitochondria and aging: an update. Cell Metab, 2017, 25: 57-71.","journal-title":"Cell Metab"},{"key":"null","doi-asserted-by":"crossref","first-page":"16804","DOI":"10.1074\/jbc.R117.789271","volume":"292","author":"Wong HS","year":"2017","unstructured":"Wong HS, Dighe PA, Mezera V, Monternier PA, Brand MD. Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions. J Biol Chem, 2017, 292: 16804-16809.","journal-title":"J Biol Chem"},{"key":"null","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.envres.2018.12.045","volume":"170","author":"Lu Q","year":"2019","unstructured":"Lu Q, Sun Y, Ares I, Anad\u00f3n A, Mart\u00ednez M, Mart\u00ednez-Larra\u00f1aga M-R, Yuan Z. Deltamethrin toxicity: a review of oxidative stress and metabolism. Environ Res, 2019, 170: 260-281.","journal-title":"Environ Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.freeradbiomed.2018.09.044","volume":"133","author":"Hino K","year":"2019","unstructured":"Hino K, Nishina S, Sasaki K, Hara Y. Mitochondrial damage and iron metabolic dysregulation in hepatitis C virus infection. Free Radic Biol Med, 2019, 133: 193-199.","journal-title":"Free Radic Biol Med"},{"key":"null","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/j.envpol.2018.06.049","volume":"241","author":"Yang Y","year":"2018","unstructured":"Yang Y, Gao J, Zhang Y, Xu W, Hao Y, Xu Z, Tao L. Natural pyrethrins induce autophagy of HepG2 cells through the activation of AMPK\/mTOR pathway. Environ Pollut, 2018, 241: 1091-1097.","journal-title":"Environ Pollut"},{"key":"null","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.etap.2003.11.005","volume":"15","author":"Kakko I","year":"2004","unstructured":"Kakko I, Toimela T, T\u00e4hti H. The toxicity of pyrethroid compounds in neural cell cultures studied with total ATP, mitochondrial enzyme activity and microscopic photographing. Environ Toxicol Phar, 2004, 15: 95-102.","journal-title":"Environ Toxicol Phar"},{"key":"null","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.pestbp.2018.07.003","volume":"150","author":"Smith A","year":"2018","unstructured":"Smith A, Yu X, Yin L. Diazinon exposure activated transcriptional factors CCAAT-enhancer-binding proteins \u03b1 (C\/EBP\u03b1) and peroxisome proliferator-activated receptor \u03b3 (PPAR\u03b3) and induced adipogenesis in 3T3-L1 preadipocytes. Pestic Biochem Physiol, 2018, 150: 48-58.","journal-title":"Pestic Biochem Physiol"},{"key":"null","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1146\/annurev-pharmtox-010818-021304","volume":"59","author":"Heindel JJ","year":"2019","unstructured":"Heindel JJ, Blumberg B. Environmental obesogens: mechanisms and controversies. Annu Rev Pharmacol, 2019, 59: 89-106.","journal-title":"Annu Rev Pharmacol"},{"key":"null","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1080\/10245332.2016.1165446","volume":"21","author":"Cao Y","year":"2016","unstructured":"Cao Y, Fang Y, Cai J, Li X, Xu F, Yuan N, Zhang S. ROS functions as an upstream trigger for autophagy to drive hematopoietic stem cell differentiation. Hematology, 2016, 21: 613-618.","journal-title":"Hematology"},{"key":"null","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.yexcr.2017.03.059","volume":"355","author":"Vinnai JR","year":"2017","unstructured":"Vinnai JR, Cumming RC, Thompson GJ, Timoshenko AV. The association between oxidative stress-induced galectins and differentiation of human promyelocytic HL-60 cells. Exp Cell Res, 2017, 355: 113-123.","journal-title":"Exp Cell Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.pneurobio.2011.01.007","volume":"93","author":"Vieira HL","year":"2011","unstructured":"Vieira HL, Alves PM, Vercelli A. Modulation of neuronal stem cell differentiation by hypoxia and reactive oxygen species. Prog Neurobiol, 2011, 93: 444-455.","journal-title":"Prog Neurobiol"},{"key":"null","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.jcma.2017.12.005","volume":"81","author":"Zhu XW","year":"2018","unstructured":"Zhu XW, Ding K, Dai XY, Ling WQ. \u03b2-aminoisobutyric acid accelerates the proliferation and differentiation of MC3T3-E1 cells via moderate activation of ROS signaling. J Chin Med Assoc, 2018, 81: 611-618.","journal-title":"J Chin Med Assoc"},{"key":"null","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.scr.2018.06.007","volume":"30","author":"Pashkovskaia N","year":"2018","unstructured":"Pashkovskaia N, Gey U, R\u00f6del G. Mitochondrial ROS direct the differentiation of murine pluripotent P19 cells. Stem Cell Res, 2018, 30: 180-191.","journal-title":"Stem Cell Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"6936","DOI":"10.3390\/ijms12106936","volume":"12","author":"Calzadilla P","year":"2011","unstructured":"Calzadilla P, Sapochnik D, Cosentino S, Diz V, Dicelio L, Calvo JC, Guerra LN. N-Acetylcysteine reduces markers of differentiation in 3T3-L1 adipocytes. Int J Mol Sci, 2011, 12: 6936-6951.","journal-title":"Int J Mol Sci"},{"key":"null","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1179\/1351000213Y.0000000066","volume":"18","author":"Calzadilla P","year":"2013","unstructured":"Calzadilla P, Gomez-Serrano M, Garcia-Santos E, Schiappacasse A, Abalde Y, Calvo JC, Peral B. N-Acetylcysteine affects obesity-related protein expression in 3T3-L1 adipocytes. Redox Rep, 2013, 18: 210-218.","journal-title":"Redox Rep"},{"key":"null","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.bbrc.2018.06.030","volume":"504","author":"Zhou X","year":"2018","unstructured":"Zhou X, Gao H, Guo Y, Chen Y, Ruan XZ. Knocking down Stard3 decreases adipogenesis with decreased mitochondrial ROS in 3T3-L1 cells. Biochem Biophys Res Commun, 2018, 504: 387-392.","journal-title":"Biochem Biophys Res Commun"},{"key":"null","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.exger.2018.07.017","volume":"112","author":"Wang K","year":"2018","unstructured":"Wang K, Chen S, Zhang C, Huang J, Wu J, Zhou H, Jin L. Enhanced ROS production leads to excessive fat accumulation through DAF-16 in Caenorhabditis elegans. Exp Gerontol, 2018, 112: 20-29.","journal-title":"Exp Gerontol"},{"key":"null","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.cmet.2016.08.002","volume":"24","author":"Altshuler-Keylin S","year":"2016","unstructured":"Altshuler-Keylin S, Shinoda K, Hasegawa Y, Ikeda K, Hong H, Kang Q, Yang Y. Beige adipocyte maintenance is regulated by autophagy-induced mitochondrial clearance. Cell Metab, 2016, 24: 402-419.","journal-title":"Cell Metab"},{"key":"null","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1089\/ars.2018.7626","volume":"31","author":"Ferhat M","year":"2018","unstructured":"Ferhat M, Funai K, Boudina S. Autophagy in adipose tissue physiology and pathophysiology. Antioxid Redox Signal, 2018, 31: 487-501.","journal-title":"Antioxid Redox Signal"},{"key":"null","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.cmet.2011.08.007","volume":"14","author":"Tormos Kathryn V","year":"2011","unstructured":"Tormos Kathryn V, Anso E, Hamanaka Robert B, Eisenbart J, Joseph J, Kalyanaraman B, Chandel NS. Mitochondrial complex III ROS regulate adipocyte differentiation. Cell Metab, 2011, 14: 537-544.","journal-title":"Cell Metab"},{"key":"null","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/nrm.2016.125","volume":"17","author":"Wrighton KH","year":"2016","unstructured":"Wrighton KH. Metabolism: mitophagy turns beige adipocytes white. Nat Rev Mol Cell Biol, 2016, 17:","journal-title":"Nat Rev Mol Cell Biol"},{"key":"null","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.phrs.2012.09.004","volume":"66","author":"Zhang Y","year":"2012","unstructured":"Zhang Y, Zeng X, Jin S. Autophagy in adipose tissue biology. Pharmacol Res, 2012, 66: 505-512.","journal-title":"Pharmacol Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1089\/ars.2010.3777","volume":"14","author":"Goldman SJ","year":"2011","unstructured":"Goldman SJ, Zhang Y, Jin S. Autophagic degradation of mitochondria in white adipose tissue differentiation. Antioxid Redox Signal, 2011, 14: 1971-1978.","journal-title":"Antioxid Redox Signal"},{"key":"null","doi-asserted-by":"crossref","first-page":"19860","DOI":"10.1073\/pnas.0906048106","volume":"106","author":"Zhang Y","year":"2009","unstructured":"Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, Jin S. Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis. Proc Natl Acad Sci U S A, 2009, 106:","journal-title":"Proc Natl Acad Sci U S A"},{"key":"null","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.4161\/auto.26563","volume":"9","author":"Ro SH","year":"2013","unstructured":"Ro SH, Jung CH, Hahn WS, Xu X, Kim YM, Yun YS, Park JM. Distinct functions of Ulk1 and Ulk2 in the regulation of lipid metabolism in adipocytes. Autophagy, 2013, 9: 2103-2114.","journal-title":"Autophagy"},{"key":"null","doi-asserted-by":"crossref","first-page":"e3100","DOI":"10.1038\/cddis.2017.495","volume":"8","author":"Slabakova E","year":"2017","unstructured":"Slabakova E, Culig Z, Remsik J, Soucek K. Alternative mechanisms of miR-34a regulation in cancer. Cell Death Dis, 2017, 8:","journal-title":"Cell Death Dis"},{"key":"null","doi-asserted-by":"crossref","first-page":"e1327","DOI":"10.1038\/cddis.2014.270","volume":"5","author":"Li XJ","year":"2014","unstructured":"Li XJ, Ren ZJ, Tang JH. MicroRNA-34a: a potential therapeutic target in human cancer. Cell Death Dis, 2014, 5:","journal-title":"Cell Death Dis"},{"key":"null","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/dom.12154","volume":"15","author":"Ferrante AW","year":"2013","unstructured":"Ferrante AW. The immune cells in adipose tissue. Diabetes Obes Metab, 2013, 15: 34-38.","journal-title":"Diabetes Obes Metab"},{"key":"null","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.tem.2012.05.011","volume":"23","author":"Schipper HS","year":"2012","unstructured":"Schipper HS, Prakken B, Kalkhoven E, Boes M. Adipose tissue-resident immune cells: key players in immunometabolism. Trends Endocrinol Metab, 2012, 23: 407-415.","journal-title":"Trends Endocrinol Metab"},{"key":"null","doi-asserted-by":"crossref","first-page":"3982","DOI":"10.2337\/db14-0272","volume":"63","author":"Seijkens T","year":"2014","unstructured":"Seijkens T, Kusters P, Chatzigeorgiou A, Chavakis T, Lutgens E. Immune cell crosstalk in obesity: a key role for costimulation?. Diabetes, 2014, 63:","journal-title":"Diabetes"},{"key":"null","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.metabol.2017.04.005","volume":"72","author":"Thomas D","year":"2017","unstructured":"Thomas D, Apovian C. Macrophage functions in lean and obese adipose tissue. Metabolism, 2017, 72: 120-143.","journal-title":"Metabolism"},{"key":"null","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1189\/jlb.0210072","volume":"88","author":"Suganami T","year":"2010","unstructured":"Suganami T, Ogawa Y. Adipose tissue macrophages: their role in adipose tissue remodeling. J Leukoc Biol, 2010, 88: 33-39.","journal-title":"J Leukoc Biol"},{"key":"null","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.cell.2017.11.019","volume":"172","author":"Rajbhandari P","year":"2018","unstructured":"Rajbhandari P, Thomas BJ, Feng AC, Hong C, Wang J, Vergnes L, Sallam T. IL-10 signaling remodels adipose chromatin architecture to limit thermogenesis and energy expenditure. Cell, 2018, 172: 218-233.","journal-title":"Cell"},{"key":"null","doi-asserted-by":"crossref","first-page":"22617","DOI":"10.1073\/pnas.1009152108","volume":"107","author":"Ricardo-Gonzalez RR","year":"2010","unstructured":"Ricardo-Gonzalez RR, Red Eagle A, Odegaard JI, Jouihan H, Morel CR, Heredia JE, Mukundan L. IL-4\/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity. Proc Natl Acad Sci U S A, 2010, 107: 22617-22622.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"null","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1172\/JCI123069","volume":"129","author":"Pan Y","year":"2019","unstructured":"Pan Y, Hui X, Hoo RLC, Ye D, Chan CYC, Feng T, Wang Y. Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation. J Clin Invest, 2019, 129: 834-849.","journal-title":"J Clin Invest"},{"key":"null","doi-asserted-by":"crossref","first-page":"442","DOI":"10.4161\/auto.27418","volume":"10","author":"Liu K","year":"2014","unstructured":"Liu K, Huang J, Xie M, Yu Y, Zhu S, Kang R, Cao L. MIR34A regulates autophagy and apoptosis by targeting HMGB1 in the retinoblastoma cell. Autophagy, 2014, 10: 442-452.","journal-title":"Autophagy"}],"container-title":["Acta Biochimica et Biophysica Sinica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/engine.scichina.com\/doi\/pdf\/EA36430330C645A1956DFC25CBB9AB57","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/engine.scichina.com\/doi\/10.1093\/abbs\/gmaa049","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/abbs\/article-pdf\/52\/8\/821\/33641997\/gmaa049.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/engine.scichina.com\/doi\/pdf\/EA36430330C645A1956DFC25CBB9AB57","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T23:42:31Z","timestamp":1666395751000},"score":1,"resource":{"primary":{"URL":"http:\/\/engine.scichina.com\/doi\/10.1093\/abbs\/gmaa049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,1]]},"references-count":81,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020,7,7]]},"published-print":{"date-parts":[[2020,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/abbs\/gmaa049","relation":{},"ISSN":["1672-9145"],"issn-type":[{"value":"1672-9145","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7,1]]}}}