{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T17:47:05Z","timestamp":1773164825320,"version":"3.50.1"},"reference-count":28,"publisher":"China Science Publishing & Media Ltd.","issue":"4","content-domain":{"domain":["engine.scichina.com"],"crossmark-restriction":false},"short-container-title":["ABBS"],"published-print":{"date-parts":[[2016,4,1]]},"DOI":"10.1093\/abbs\/gmw009","type":"journal-article","created":{"date-parts":[[2016,3,24]],"date-time":"2016-03-24T16:15:06Z","timestamp":1458836106000},"page":"378-384","update-policy":"https:\/\/doi.org\/10.1360\/scp-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["Atorvastatin blocks increased l-type Ca&amp;lt;sup&amp;gt;2+&amp;lt;\/sup&amp;gt; current and cell injury elicited by angiotensin II via inhibiting oxide stress"],"prefix":"10.3724","volume":"48","author":[{"given":"Yanzhuo","family":"Ma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingfeng","family":"Kong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuying","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongmei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2026","published-online":{"date-parts":[[2016,4,1]]},"reference":[{"key":"null","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1097\/FJC.0b013e3180a72606","volume":"50","author":"Rugale C","year":"2007","unstructured":"Rugale C, Delbosc S, Mimran A, Jover B. Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine. J Cardiovasc Pharmacol, 2007, 50: 293-298.","journal-title":"J Cardiovasc Pharmacol"},{"key":"null","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s10863-013-9514-z","volume":"45","author":"Ozturk N","year":"2013","unstructured":"Ozturk N, Yaras N, Ozmen A, Ozdemir S. Long-term administration of rosuvastatin prevents contractile and electrical remodelling of diabetic rat heart. J Bioenerg Biomembr, 2013, 45: 343-352.","journal-title":"J Bioenerg Biomembr"},{"key":"null","doi-asserted-by":"crossref","first-page":"e66404","DOI":"10.1371\/journal.pone.0066404","volume":"8","author":"Seto SW","year":"2013","unstructured":"Seto SW, Au AL, Poon CC, Zhang Q, Li RW, Yeung JH, Kong SK. Acute simvastatin inhibits K ATP channels of porcine coronary artery myocytes. PLoS One, 2013, 8:","journal-title":"PLoS One"},{"key":"null","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1038\/sj.bjp.0707327","volume":"151","author":"Seto SW","year":"2007","unstructured":"Seto SW, Au AL, Lam TY, Chim SS, Lee SM, Wan S, Tjiu DC. Modulation by simvastatin of iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine coronary artery smooth muscle cells. Br J Pharmacol, 2007, 151: 987-997.","journal-title":"Br J Pharmacol"},{"key":"null","doi-asserted-by":"crossref","first-page":"236","DOI":"10.7150\/ijbs.8.236","volume":"8","author":"Su F","year":"2012","unstructured":"Su F, Shi M, Yan Z, Ou D, Li J, Lu Z, Zheng Q. Simvastatin modulates remodeling of Kv4.3 expression in rat hypertrophied cardiomyocytes. Int J Biol Sci, 2012, 8: 236-248.","journal-title":"Int J Biol Sci"},{"key":"null","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1002\/jps.22809","volume":"101","author":"Plante I","year":"2012","unstructured":"Plante I, Vigneault P, Drolet B, Turgeon J. Rosuvastatin blocks hERG current and prolongs cardiac repolarization. J Pharm Sci, 2012, 101: 868-878.","journal-title":"J Pharm Sci"},{"key":"null","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/00029330-200803020-00017","volume":"121","author":"Ding C","year":"2008","unstructured":"Ding C, Fu XH, He ZS, Chen HX, Xue L, Li JX. Cardioprotective effects of simvastatin on reversing electrical remodeling induced by myocardial ischemia-reperfusion in normocholesterolemic rabbits. Chin Med J, 2008, 121: 551-556.","journal-title":"Chin Med J"},{"key":"null","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.lfs.2010.09.010","volume":"87","author":"Laszlo R","year":"2010","unstructured":"Laszlo R, Menzel KA, Bentz K, Schreiner B, Kettering K, Eick C, Schreieck J. Atorvastatin treatment affects atrial ion currents and their tachycardia-induced remodeling in rabbits. Life Sci, 2010, 87: 507-513.","journal-title":"Life Sci"},{"key":"null","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.pharmthera.2006.12.002","volume":"114","author":"Tamargo J","year":"2007","unstructured":"Tamargo J, Caballero R, Gomez R, Nunez L, Vaquero M, Delpon E. Lipid-lowering therapy with statins, a new approach to antiarrhythmic therapy. Pharmacol Ther, 2007, 114: 107-126.","journal-title":"Pharmacol Ther"},{"key":"null","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1034\/j.1600-0773.2003.930304.x","volume":"93","author":"Bergdahl A","year":"2003","unstructured":"Bergdahl A, Persson E, Hellstrand P, Sward K. Lovastatin induces relaxation and inhibits L-type Ca(2+) current in the rat basilar artery. Pharmacol Toxicol, 2003, 93: 128-134.","journal-title":"Pharmacol Toxicol"},{"key":"null","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1161\/CIRCULATIONAHA.105.581397","volume":"113","author":"Zhang M","year":"2006","unstructured":"Zhang M, Kho AL, Anilkumar N, Chibber R, Pagano PJ, Shah AM, Cave AC. Glycated proteins stimulate reactive oxygen species production in cardiac myocytes: involvement of Nox2 (gp91phox)-containing NADPH oxidase. Circulation, 2006, 113: 1235-1243.","journal-title":"Circulation"},{"key":"null","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1161\/01.RES.0000218989.52072.e7","volume":"98","author":"Zhou C","year":"2006","unstructured":"Zhou C, Ziegler C, Birder LA, Stewart AF, Levitan ES. Angiotensin II and stretch activate NADPH oxidase to destabilize cardiac Kv4.3 channel mRNA. Circ Res, 2006, 98: 1040-1047.","journal-title":"Circ Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"H1528","DOI":"10.1152\/ajpheart.2001.280.4.H1528","volume":"280","author":"Aiello EA","year":"2001","unstructured":"Aiello EA, Cingolani HE. Angiotensin II stimulates cardiac L-type Ca(2+) current by a Ca(2+)- and protein kinase C-dependent mechanism. Am J Physiol Heart Circ Physiol, 2001, 280: H1528-H1536.","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"null","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1161\/01.CIR.0000091084.46500.BB","volume":"108","author":"Maack C","year":"2003","unstructured":"Maack C, Kartes T, Kilter H, Schafers HJ, Nickenig G, Bohm M, Laufs U. Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment. Circulation, 2003, 108: 1567-1574.","journal-title":"Circulation"},{"key":"null","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1161\/01.RES.0000261657.76299.ff","volume":"100","author":"Doerries C","year":"2007","unstructured":"Doerries C, Grote K, Hilfiker-Kleiner D, Luchtefeld M, Schaefer A, Holland SM, Sorrentino S. Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling\/dysfunction and survival after myocardial infarction. Circ Res, 2007, 100: 894-903.","journal-title":"Circ Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1056\/NEJM199209033271001","volume":"327","author":"Pfeffer MA","year":"1992","unstructured":"Pfeffer MA, Braunwald E, Moye LA, Basta L, Brown EJ, Cuddy TE, Davis BR. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med, 1992, 327: 669-677.","journal-title":"N Engl J Med"},{"key":"null","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1056\/NEJMoa032292","volume":"349","author":"Pfeffer MA","year":"2003","unstructured":"Pfeffer MA, McMurray JJ, Velazquez EJ, Rouleau JL, Kober L, Maggioni AP, Solomon SD. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med, 2003, 349: 1893-1906.","journal-title":"N Engl J Med"},{"key":"null","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.abb.2004.08.001","volume":"434","author":"Waring P","year":"2005","unstructured":"Waring P. Redox active calcium ion channels and cell death. Arch Biochem Biophys, 2005, 434: 33-42.","journal-title":"Arch Biochem Biophys"},{"key":"null","doi-asserted-by":"crossref","first-page":"a72","DOI":"10.2741\/pessah","volume":"7","author":"Pessah IN","year":"2002","unstructured":"Pessah IN, Kim KH, Feng W. Redox sensing properties of the ryanodine receptor complex. Front Biosci, 2002, 7: a72-a79.","journal-title":"Front Biosci"},{"key":"null","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1038\/415198a","volume":"415","author":"Bers DM","year":"2002","unstructured":"Bers DM. Cardiac excitation-contraction coupling. Nature, 2002, 415: 198-205.","journal-title":"Nature"},{"key":"null","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1161\/CIRCEP.107.754564","volume":"1","author":"Nattel S","year":"2008","unstructured":"Nattel S, Burstein B, Dobrev D. Atrial remodeling and atrial fibrillation: mechanisms and implications. Circ Arrhythm Electrophysiol, 2008, 1: 62-73.","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"null","doi-asserted-by":"crossref","first-page":"7159","DOI":"10.1074\/jbc.M308057200","volume":"279","author":"Wang MC","year":"2004","unstructured":"Wang MC, Collins RF, Ford RC, Berrow NS, Dolphin AC, Kitmitto A. The three-dimensional structure of the cardiac L-type voltage-gated calcium channel: comparison with the skeletal muscle form reveals a common architectural motif. J Biol Chem, 2004, 279: 7159-7168.","journal-title":"J Biol Chem"},{"key":"null","doi-asserted-by":"crossref","first-page":"3306","DOI":"10.1172\/JCI27167","volume":"115","author":"Bodi I","year":"2005","unstructured":"Bodi I, Mikala G, Koch SE, Akhter SA, Schwartz A. The L-type calcium channel in the heart: the beat goes on. J Clin Invest, 2005, 115: 3306-3317.","journal-title":"J Clin Invest"},{"key":"null","doi-asserted-by":"crossref","first-page":"491","DOI":"10.3390\/medicina44070064","volume":"44","author":"Treinys R","year":"2008","unstructured":"Treinys R, Jurevicius J. L-type Ca2+ channels in the heart: structure and regulation. Medicina, 2008, 44: 491-499.","journal-title":"Medicina"},{"key":"null","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1161\/CIRCRESAHA.108.175463","volume":"103","author":"Qi XY","year":"2008","unstructured":"Qi XY, Yeh YH, Xiao L, Burstein B, Maguy A, Chartier D, Villeneuve LR. Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current. Circ Res, 2008, 103: 845-854.","journal-title":"Circ Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"H377","DOI":"10.1152\/ajpheart.00289.2012","volume":"303","author":"Deo SH","year":"2012","unstructured":"Deo SH, Fisher JP, Vianna LC, Kim A, Chockalingam A, Zimmerman MC, Zucker IH. Statin therapy lowers muscle sympathetic nerve activity and oxidative stress in patients with heart failure. Am J Physiol Heart Circ Physiol, 2012, 303: H377-H385.","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"null","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.1365-2362.2011.02628.x","volume":"42","author":"Chiu CZ","year":"2012","unstructured":"Chiu CZ, Wang BW, Shyu KG. Use of atorvastatin to inhibit hypoxia-induced myocardin expression. Eur J Clin Invest, 2012, 42: 564-571.","journal-title":"Eur J Clin Invest"},{"key":"null","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S0008-6363(00)00106-1","volume":"47","author":"Gray DF","year":"2000","unstructured":"Gray DF, Bundgaard H, Hansen PS, Buhagiar KA, Mihailidou AS, Jessup W, Kjeldsen K. HMG CoA reductase inhibition reduces sarcolemmal Na(+)-K(+) pump density. Cardiovasc Res, 2000, 47: 329-335.","journal-title":"Cardiovasc Res"}],"container-title":["Acta Biochimica et Biophysica Sinica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/engine.scichina.com\/doi\/pdf\/3C1240F14A334AEFAD92C3DE13841E93","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/engine.scichina.com\/doi\/10.1093\/abbs\/gmw009","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/engine.scichina.com\/doi\/pdf\/3C1240F14A334AEFAD92C3DE13841E93","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T08:16:27Z","timestamp":1718439387000},"score":1,"resource":{"primary":{"URL":"http:\/\/engine.scichina.com\/doi\/10.1093\/abbs\/gmw009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,1]]},"references-count":28,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2016,4,1]]},"published-print":{"date-parts":[[2016,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/abbs\/gmw009","relation":{},"ISSN":["1672-9145"],"issn-type":[{"value":"1672-9145","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4,1]]}}}