{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T03:43:32Z","timestamp":1774323812648,"version":"3.50.1"},"reference-count":21,"publisher":"China Science Publishing & Media Ltd.","issue":"6","license":[{"start":{"date-parts":[[2018,4,25]],"date-time":"2018-04-25T00:00:00Z","timestamp":1524614400000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"funder":[{"name":"Major Research Plan of the National Natural Science Foundation of China","award":["91539205"],"award-info":[{"award-number":["91539205"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770393"],"award-info":[{"award-number":["81770393"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["engine.scichina.com"],"crossmark-restriction":false},"short-container-title":["ABBS"],"published-print":{"date-parts":[[2018,4,1]]},"DOI":"10.1093\/abbs\/gmy038","type":"journal-article","created":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T19:13:05Z","timestamp":1523560385000},"page":"560-566","update-policy":"https:\/\/doi.org\/10.1360\/scp-crossmark-policy-page","source":"Crossref","is-referenced-by-count":10,"title":["The inhibitory effect of BK&amp;lt;sub&amp;gt;Ca&amp;lt;\/sub&amp;gt; channels induced by autoantibodies against angiotensin II type 1 receptor is independent of AT1R"],"prefix":"10.3724","volume":"50","author":[{"given":"Peng","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengli","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingwei","family":"Bian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaochen","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huirong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2026","published-online":{"date-parts":[[2018,4,25]]},"reference":[{"key":"null","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0140-6736(00)03577-7","volume":"357","author":"Roberts JM","year":"2001","unstructured":"Roberts JM, Cooper DW. Pathogenesis and genetics of pre-eclampsia. Lancet, 2001, 357: 53-56.","journal-title":"Lancet"},{"key":"null","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1161\/HYPERTENSIONAHA.107.107607","volume":"51","author":"Huppertz B","year":"2008","unstructured":"Huppertz B. Placental origins of preeclampsia: challenging the current hypothesis. Hypertension, 2008, 51: 970-975.","journal-title":"Hypertension"},{"key":"null","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1172\/JCI4106","volume":"103","author":"Wallukat G","year":"1999","unstructured":"Wallukat G, Homuth V, Fischer T, Lindschau C, Horstkamp B, Jupner A, Baur E. Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor. J Clin Invest, 1999, 103: 945-952.","journal-title":"J Clin Invest"},{"key":"null","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1097\/HJH.0b013e328304dbff","volume":"26","author":"Yang X","year":"2008","unstructured":"Yang X, Wang F, Chang H, Zhang S, Yang L, Wang X, Cheng X. Autoantibody against AT1 receptor from preeclamptic patients induces vasoconstriction through angiotensin receptor activation. J Hypertens, 2008, 26: 1629-1635.","journal-title":"J Hypertens"},{"key":"null","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1016\/j.febslet.2010.02.045","volume":"584","author":"Hill MA","year":"2010","unstructured":"Hill MA, Yang Y, Ella SR, Davis MJ, Braun AP. Large conductance, Ca2+-activated K+ channels (BKCa) and arteriolar myogenic signaling. FEBS Lett, 2010, 584: 2033-2042.","journal-title":"FEBS Lett"},{"key":"null","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1161\/HYPERTENSIONAHA.111.179952","volume":"58","author":"Hu XQ","year":"2011","unstructured":"Hu XQ, Xiao D, Zhu R, Huang X, Yang S, Wilson S, Zhang L. Pregnancy upregulates large-conductance Ca(2+)-activated K(+) channel activity and attenuates myogenic tone in uterine arteries. Hypertension, 2011, 58: 1132-1139.","journal-title":"Hypertension"},{"key":"null","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s11010-014-2221-1","volume":"398","author":"Gao N","year":"2014","unstructured":"Gao N, Wang H, Zhang X, Yang Z. The inhibitory effect of angiotensin II on BKCa channels in podocytes via oxidative stress. Mol Cell Biochem, 2014, 398: 217-222.","journal-title":"Mol Cell Biochem"},{"key":"null","doi-asserted-by":"crossref","first-page":"L1275","DOI":"10.1152\/ajplung.00259.2003","volume":"286","author":"Barman SA","year":"2004","unstructured":"Barman SA, Zhu S, White RE. PKC activates BKCa channels in rat pulmonary arterial smooth muscle via cGMP-dependent protein kinase. Am J Physiology Lung Cell Mol Physiol, 2004, 286: L1275-L1281.","journal-title":"Am J Physiology Lung Cell Mol Physiol"},{"key":"null","first-page":"1","volume":"2016","author":"Wei M","year":"2016","unstructured":"Wei M, Zhao C, Zhang S, Wang L, Liu H, Ma X. Preparation and biological activity of the monoclonal antibody against the second extracellular loop of the angiotensin II type 1 receptor. Clin Dev Immunol, 2016, 2016: 1-10.","journal-title":"Clin Dev Immunol"},{"key":"null","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1038\/nm.1856","volume":"14","author":"Zhou CC","year":"2008","unstructured":"Zhou CC, Zhang Y, Irani RA, Zhang H, Mi T, Popek EJ, Hicks MJ. Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice. Nat Med, 2008, 14: 855-862.","journal-title":"Nat Med"},{"key":"null","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1093\/emboj\/19.5.942","volume":"19","author":"Lin YF","year":"2000","unstructured":"Lin YF, Jan YN, Jan LY. Regulation of ATP\u2010sensitive potassium channel function by protein kinase A\u2010mediated phosphorylation in transfected HEK293 cells. EMBO J, 2000, 19: 942-955.","journal-title":"EMBO J"},{"key":"null","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1161\/01.RES.77.5.936","volume":"77","author":"White RE","year":"1995","unstructured":"White RE, Darkow DJ, Lang JL. Estrogen relaxes coronary arteries by opening BKCa channels through a cGMP-dependent mechanism. Circ Res, 1995, 77: 936-942.","journal-title":"Circ Res"},{"key":"null","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1089\/ars.2011.4365","volume":"17","author":"Zhang S","year":"2012","unstructured":"Zhang S, Zhang X, Yang L, Yan Z, Yan L, Tian J, Li X. Increased susceptibility to metabolic syndrome in adult offspring of angiotensin type 1 receptor autoantibody-positive rats. Antioxid Redox Signal, 2012, 17: 733-743.","journal-title":"Antioxid Redox Signal"},{"key":"null","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1097\/00000539-200003000-00009","volume":"90","author":"Samain E","year":"2000","unstructured":"Samain E, Bouillier H, Marty J, Safar M, Dagher G. The effect of propofol on angiotensin II-induced Ca(2+) mobilization in aortic smooth muscle cells from normotensive and hypertensive rats. Anesth Analg, 2000, 90: 546-552.","journal-title":"Anesth Analg"},{"key":"null","doi-asserted-by":"crossref","first-page":"e57451","DOI":"10.1371\/journal.pone.0057451","volume":"8","author":"Brereton MF","year":"2013","unstructured":"Brereton MF, Wareing M, Jones RL, Greenwood SL. Characterisation of K+ channels in human fetoplacental vascular smooth muscle cells. PLoS One, 2013, 8:","journal-title":"PLoS One"},{"key":"null","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1085\/jgp.200509421","volume":"127","author":"Ma Z","year":"2006","unstructured":"Ma Z, Lou XJ, Horrigan FT. Role of charged residues in the S1\u2013S4 voltage sensor of BK channels. J Gen Physiol, 2006, 127: 309-328.","journal-title":"J Gen Physiol"},{"key":"null","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1523\/JNEUROSCI.22-05-01550.2002","volume":"22","author":"Wang YW","year":"2002","unstructured":"Wang YW, Ding JP, Xia XM, Lingle CJ. Consequences of the stoichiometry of Slo1 alpha and auxiliary beta subunits on functional properties of large-conductance Ca2+-activated K+ channels. J Neurosci, 2002, 22: 1550-1561.","journal-title":"J Neurosci"},{"key":"null","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.tins.2010.06.004","volume":"33","author":"Lee US","year":"2010","unstructured":"Lee US, Cui J. BK channel activation: structural and functional insights. Trends Neurosci, 2010, 33: 415-423.","journal-title":"Trends Neurosci"},{"key":"null","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1085\/jgp.116.3.411","volume":"116","author":"Cox DH","year":"2000","unstructured":"Cox DH, Aldrich RW. Role of the beta1 subunit in large-conductance Ca(2+)-activated K(+) channel gating energetics. Mechanisms of enhanced Ca(2+) sensitivity. J Gen Physiol, 2000, 116: 411-432.","journal-title":"J Gen Physiol"},{"key":"null","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1038\/nrn1992","volume":"7","author":"Salkoff L","year":"2006","unstructured":"Salkoff L, Butler A, Ferreira G, Santi C, Wei A. High-conductance potassium channels of the SLO family. Nat Rev Neurosci, 2006, 7: 921-931.","journal-title":"Nat Rev Neurosci"},{"key":"null","first-page":"H912","volume":"258","author":"Toro L","year":"1990","unstructured":"Toro L, Amador M, Stefani E. ANG II inhibits calcium-activated potassium channels from coronary smooth muscle in lipid bilayers. Am J Physio, 1990, 258: H912-H915.","journal-title":"Am J Physio"}],"container-title":["Acta Biochimica et Biophysica Sinica"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/engine.scichina.com\/doi\/pdf\/16EBDA48D5834C608721697FDB22DE57","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/engine.scichina.com\/doi\/10.1093\/abbs\/gmy038","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/engine.scichina.com\/doi\/pdf\/16EBDA48D5834C608721697FDB22DE57","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T06:10:19Z","timestamp":1660889419000},"score":1,"resource":{"primary":{"URL":"http:\/\/engine.scichina.com\/doi\/10.1093\/abbs\/gmy038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,1]]},"references-count":21,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2018,4,25]]},"published-print":{"date-parts":[[2018,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/abbs\/gmy038","relation":{},"ISSN":["1672-9145"],"issn-type":[{"value":"1672-9145","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4,1]]}}}