{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:22:45Z","timestamp":1791897765776,"version":"4.3.4"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T00:00:00Z","timestamp":1589760000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100001545","name":"Children's Tumor Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001545","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Neurofibromatosis (NF) is a rare genetic disorder associated with substantial deficits in quality of life (QoL). We have previously shown that in this population the Relaxation Response Resiliency Program for NF (3RP-NF) delivered via live videoconferencing is associated with sustained improvement in QoL from baseline through 6-month follow-up over and above an attention placebo control..<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Purpose<\/jats:title>\n                  <jats:p>To examine between- and within-group changes in QoL domains from baseline to 1-year follow-up and 6-month to 1-year follow-up.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We enrolled and randomized 63 adults with NF. Of these, 52 completed the 6-month follow-up and 53 completed 1-year follow-up. We assessed QoL with the World Health Organization Quality of Life\u2014Brief.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Participation in the 3RP-NF was associated with sustained improvement from baseline to 1 year in physical health QoL (12.68; 95% confidence interval [CI]: 1.76 to 23.59; p =.024) and social relations QoL (16.81; 95% CI: 3.03 to 30.59; p =.018) but not psychological and environmental QoL, over and above the control (between group changes). Participants in the 3RP-NF improved from baseline to 1 year in psychological (8.16; 95% CI: 1.17 to 15.14; p =.023) and social relations QoL (9.93; 95% CI: 1.10 to 18.77; p = .028; within-group changes). There were no other significant differences between or within groups from baseline\/6 months to 1 year.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The live video 3RP-NF shows promise in improving QoL dimensions over the course of 1 year. Results should be replicated in a fully powered randomized controlled trial.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Clinical Trial information<\/jats:title>\n                  <jats:p>ClinicalTrials.gov NCT03406208.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/abm\/kaaa030","type":"journal-article","created":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T12:49:22Z","timestamp":1589806162000},"page":"77-81","source":"Crossref","is-referenced-by-count":9,"title":["Mind\u2013Body Therapy via Videoconferencing in Patients With Neurofibromatosis: Analyses of 1-Year Follow-up"],"prefix":"10.1093","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7282-8865","authenticated-orcid":false,"given":"Ethan G","family":"Lester","sequence":"first","affiliation":[{"name":"Integrated Brain Health Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, One Bowdoin Square, Boston, MA, USA"},{"name":"Department of Psychiatry, Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa V","family":"Gates","sequence":"additional","affiliation":[{"name":"Integrated Brain Health Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, One Bowdoin Square, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3994-6488","authenticated-orcid":false,"given":"Ana-Maria","family":"Vranceanu","sequence":"additional","affiliation":[{"name":"Integrated Brain Health Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, One Bowdoin Square, Boston, MA, USA"},{"name":"Department of Psychiatry, Harvard Medical School, Boston, MA, 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A report from the WHOQOL group","volume":"13","author":"Skevington","year":"2004","journal-title":"Qual Life Res."},{"issue":"5","key":"2021021216473743400_CIT0013","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1007\/s00520-012-1664-8","article-title":"The minimal clinical important difference in the World Health Organization Quality of Life instrument\u2014100","volume":"21","author":"Den Oudsten","year":"2013","journal-title":"Support Care Cancer."},{"issue":"10","key":"2021021216473743400_CIT0014","doi-asserted-by":"crossref","first-page":"e11008","DOI":"10.2196\/11008","article-title":"Mind-body treatment for international English-speaking adults with neurofibromatosis via live videoconferencing: protocol for a single-blind randomized controlled trial","volume":"7","author":"Vranceanu","year":"2018","journal-title":"JMIR Res Protoc."}],"container-title":["Annals of Behavioral Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/abm\/article-pdf\/55\/1\/77\/36247187\/kaaa030.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/abm\/article-pdf\/55\/1\/77\/36247187\/kaaa030.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,13]],"date-time":"2021-02-13T01:42:45Z","timestamp":1613180565000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/abm\/article\/55\/1\/77\/5838775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,18]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,5,18]]},"published-print":{"date-parts":[[2021,2,12]]}},"URL":"https:\/\/doi.org\/10.1093\/abm\/kaaa030","relation":{},"ISSN":["0883-6612","1532-4796"],"issn-type":[{"value":"0883-6612","type":"print"},{"value":"1532-4796","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,1,1]]},"published":{"date-parts":[[2020,5,18]]}}}