{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:55:06Z","timestamp":1740138906035,"version":"3.37.3"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"5","funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["HG200387-08"],"award-info":[{"award-number":["HG200387-08"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Future-oriented emotions are associated with consequential health decision-making, including genomic testing decisions. However, little is known about the relative role of various future-oriented emotions in such decisions. Moreover, most research on predictors of decision making regarding genomic testing is conducted with white participants.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Purpose<\/jats:title>\n                  <jats:p>This study examined the role of future-oriented emotions in decisions to receive genomic testing results in U.S. individuals of African descent.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We analyzed cross-sectional survey data from a genomic sequencing cohort (N = 408). All participants identified as African, African-American, or Afro-Caribbean (Mage = 56.3, 74.7% female). Participants completed measures assessing anticipatory affect (worry about genetic testing results), anticipated distress (feeling devastated if genetic testing showed an increased risk for fatal disease), and anticipated regret (regretting a decision not to learn results). Outcomes were intentions for learning actionable, nonactionable, and carrier results.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Anticipated regret was robustly positively associated with intentions to receive actionable (b = 0.28, p &amp;lt; .001), nonactionable (b = 0.39, p &amp;lt; .001), and carrier (b = 0.30, p &amp;lt; .001) results. Anticipated distress was negatively associated with intentions to receive nonactionable results only (b = \u22120.16, p &amp;lt; .01). Anticipatory negative affect (worry) was not associated with intentions. At higher levels of anticipated regret, anticipated distress was less strongly associated with intentions to receive nonactionable results (b = 0.14, p = .02).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our results highlight the role of future-oriented emotions in genomic testing among participants who are typically underrepresented in genomic testing studies and behavioral medicine broadly. Future work should examine whether interventions targeting future-oriented emotions such as anticipated regret may have clinically meaningful effects in genetic counseling in similar cohorts.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/abm\/kaac069","type":"journal-article","created":{"date-parts":[[2022,11,10]],"date-time":"2022-11-10T18:43:42Z","timestamp":1668105822000},"page":"418-423","source":"Crossref","is-referenced-by-count":1,"title":["Future-oriented Emotions and Decisions to Receive Genomic Testing Results Among U.S. Adults of African Ancestry"],"prefix":"10.1093","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3511-4978","authenticated-orcid":false,"given":"Arielle S","family":"Gillman","sequence":"first","affiliation":[{"name":"Basic Biobehavioral and Psychological Sciences Branch, Behavioral Research Program, National Cancer Institute, National Institutes of Health , Bethesda, MD , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina A","family":"Iles","sequence":"additional","affiliation":[{"name":"Office of the Associate Director, Behavioral Research Program, National Cancer Institute, National Institutes of Health , Bethesda, MD , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William M P","family":"Klein","sequence":"additional","affiliation":[{"name":"Office of the Associate Director, Behavioral Research Program, National Cancer Institute, National Institutes of Health , Bethesda, MD , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara B","family":"Biesecker","sequence":"additional","affiliation":[{"name":"Research Triangle Institute International , Washington, DC , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie L","family":"Lewis","sequence":"additional","affiliation":[{"name":"Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health , Bethesda, MD , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie G","family":"Biesecker","sequence":"additional","affiliation":[{"name":"Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health , Bethesda, MD , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1069-9989","authenticated-orcid":false,"given":"Rebecca A","family":"Ferrer","sequence":"additional","affiliation":[{"name":"Basic Biobehavioral and Psychological Sciences Branch, Behavioral Research Program, National Cancer Institute, National Institutes of Health , Bethesda, MD , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,11,10]]},"reference":[{"issue":"12","key":"2023042206301930000_CIT0001","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1037\/hea0000683","article-title":"Behavioral 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