{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:27:41Z","timestamp":1785770861709,"version":"3.56.0"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2020,1,11]],"date-time":"2020-01-11T00:00:00Z","timestamp":1578700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["15GRNT25700346"],"award-info":[{"award-number":["15GRNT25700346"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Study of Early Child Care and Youth Development"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Obesity is a cardiovascular disease risk factor and affects approximately 13.7 million U.S. children and adolescents between the ages 2 and 19 years old in 2015\u20132016.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To determine the relationship between children\u2019s average long-term exposure to maternal depressive symptoms age 1 month to Grade 6 and adolescents\u2019 body mass index (BMI) z-score at age 15 mediated by the adolescents\u2019 depressive symptom experience.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 1,364 infants and their families from the Eunice Kennedy Shriver National Institute of Child Health and Human Development Study of Early Child Care and Youth Development were recruited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mediation analyses revealed a significant relationship between children\u2019s average long-term exposure to maternal depressive symptoms from age 1 month to Grade 6 and adolescents\u2019 BMI z-score at age 15 (total effect = 0.015, p = .013, 95% confidence interval (CI): 0.0032, 0.027). The adolescents\u2019 experience of depressive symptoms significantly mediated this relationship (indirect effect = 0.0021, bias-corrected bootstrapped 95% CI: 0.0004, 0.0044), with this mediated relationship more pronounced in girls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Findings indicate the possible existence of a mediating role of adolescents\u2019 depressive symptoms experience in the pathway from average long-term exposure to maternal depressive symptoms during children\u2019s early life to adolescents\u2019 elevated BMI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/abm\/kaz069","type":"journal-article","created":{"date-parts":[[2020,1,11]],"date-time":"2020-01-11T08:26:23Z","timestamp":1578731183000},"page":"510-517","source":"Crossref","is-referenced-by-count":8,"title":["Adolescents\u2019 Depressive Symptom Experience Mediates the Impact of Long-Term Exposure to Maternal Depression Symptoms on Adolescents\u2019 Body Mass Index"],"prefix":"10.1093","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4389-7455","authenticated-orcid":false,"given":"Amber R","family":"Cordola Hsu","sequence":"first","affiliation":[{"name":"School of Community and Global Health, Claremont Graduate University, The Claremont Colleges , Claremont, CA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongzheng","family":"Niu","sequence":"additional","affiliation":[{"name":"School of Community and Global Health, Claremont Graduate University, The Claremont Colleges , Claremont, CA,","place":["USA"]},{"name":"Department of Epidemiology and Environmental Health, University at Buffalo, State University of New York , Buffalo, NY,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomeng","family":"Lei","sequence":"additional","affiliation":[{"name":"School of Community and Global Health, Claremont Graduate University, The Claremont Colleges , Claremont, CA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Kiresich","sequence":"additional","affiliation":[{"name":"School of Community and Global Health, Claremont Graduate University, The Claremont Colleges , Claremont, CA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yawen","family":"Li","sequence":"additional","affiliation":[{"name":"School of Social Work, San Diego State University , San Diego, CA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Chin","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Psychology, Claremont McKenna College, The Claremont Colleges , Claremont, CA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Xie","sequence":"additional","affiliation":[{"name":"School of Community and Global Health, Claremont Graduate University, The Claremont Colleges , Claremont, CA,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,1,11]]},"reference":[{"key":"2026041420203477700_CIT0001","author":"Center for Disease Control and Prevention (CDC)"},{"key":"2026041420203477700_CIT0002","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jpeds.2006.08.042","article-title":"Cardiovascular risk factors and excess adiposity among overweight children and adolescents: The Bogalusa Heart Study","volume":"150","author":"Freedman","year":"2007","journal-title":"J Pediatr."},{"key":"2026041420203477700_CIT0003","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1056\/NEJM199709253371309","article-title":"Obesity in adulthood\u2014The importance of childhood and parental obesity","volume":"337","author":"Bouchard","year":"1997","journal-title":"N Engl J Med."},{"key":"2026041420203477700_CIT0004","volume-title":"Growing Up with a Single Parent. 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