{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:14:41Z","timestamp":1792631681890,"version":"4.5.0"},"reference-count":96,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T00:00:00Z","timestamp":1569801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advances in Nutrition"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1093\/advances\/nmz100","type":"journal-article","created":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T23:18:20Z","timestamp":1567034300000},"page":"185-199","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Perspective: Integration to Implementation (I-to-I) and the Micronutrient Forum\u2014Addressing the Safety and Effectiveness of Vitamin A Supplementation"],"prefix":"10.1016","volume":"11","author":[{"given":"Daniel J","family":"Raiten","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3135-084X","authenticated-orcid":false,"given":"Ian","family":"Darnton-Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherry A","family":"Tanumihardjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parminder S","family":"Suchdev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8656-2906","authenticated-orcid":false,"given":"Emorn","family":"Udomkesmalee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dora In\u00e9s","family":"Mazariegos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musonda","family":"Mofu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Kraemer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1435-0306","authenticated-orcid":false,"given":"Homero","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/advances\/nmz100_bib1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3945\/an.115.008581","article-title":"Integration to Implementation and the Micronutrient Forum: a coordinated approach for global nutrition. Case study application: safety and effectiveness of iron interventions","volume":"7","author":"Raiten","year":"2016","journal-title":"Adv Nutr"},{"key":"10.1093\/advances\/nmz100_bib2","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/S0140-6736(13)60843-0","article-title":"Nutrition-sensitive interventions and programmes: how can they help to accelerate progress in improving maternal and child nutrition?","volume":"382","author":"Ruel","year":"2013","journal-title":"Lancet"},{"issue":"2","key":"10.1093\/advances\/nmz100_bib3","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1467-3010.1975.tb01158.x","article-title":"Nutrition and infection","volume":"3","author":"Waterlow","year":"1975","journal-title":"Nutrition Bull"},{"issue":"5","key":"10.1093\/advances\/nmz100_bib4","doi-asserted-by":"crossref","first-page":"1039S","DOI":"10.3945\/jn.114.194571","article-title":"Inflammation and nutritional science for programs\/policies and interpretation of research evidence (INSPIRE)","volume":"145","author":"Raiten","year":"2015","journal-title":"J Nutr"},{"key":"10.1093\/advances\/nmz100_bib5","doi-asserted-by":"crossref","first-page":"349","DOI":"10.3945\/an.115.010215","article-title":"Overview of the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project","volume":"7","author":"Suchdev","year":"2016","journal-title":"Adv Nutr"},{"issue":"3","key":"10.1093\/advances\/nmz100_bib6","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3390\/nu9030190","article-title":"Vitamin A supplementation programs and country-level evidence of vitamin A deficiency","volume":"9","author":"Wirth","year":"2017","journal-title":"Nutrients"},{"key":"10.1093\/advances\/nmz100_bib7","series-title":"Global prevalence of vitamin A deficiency in populations at risk 1995\u20132005","author":"World Health Organization","year":"2005"},{"issue":"1","key":"10.1093\/advances\/nmz100_bib8","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/ije\/dyu274","article-title":"Premature abandonment of global vitamin A supplementation programmes is not prudent!","volume":"44","author":"Bhutta","year":"2015","journal-title":"Int J Epidemiol"},{"issue":"9","key":"10.1093\/advances\/nmz100_bib9","doi-asserted-by":"crossref","first-page":"e528","DOI":"10.1016\/S2214-109X(15)00039-X","article-title":"Trends and mortality effects of vitamin A deficiency in children in 138 low-income and middle-income countries between 1991 and 2013: a pooled analysis of population-based surveys","volume":"3","author":"Stevens","year":"2015","journal-title":"Lance Glob Health"},{"key":"10.1093\/advances\/nmz100_bib10","series-title":"Consolidado de legislaci\u00f3n para fortificaci\u00f3n de alimentos","author":"Comisi\u00f3n Nacional para la Fortificaci\u00f3n, Enriquecimiento y\/o Equiparaci\u00f3n de Alimentos","year":"2010"},{"key":"10.1093\/advances\/nmz100_bib11","series-title":"Guatemala: encuesta nacional de micronutrientes 2009\u20132010, ENMICRON","author":"Ministerio de Salud P\u00fablica y Asistencia Social (NSPAS)","year":"2012"},{"issue":"2","key":"10.1093\/advances\/nmz100_bib12","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1177\/0379572118774229","article-title":"Food fortification in low- and middle-income countries: a review of programs, trends, challenges and evidence-gaps","volume":"39","author":"Osendarp","year":"2018","journal-title":"Food Nutr Bull"},{"key":"10.1093\/advances\/nmz100_bib13","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1177\/15648265100311S105","article-title":"Vitamin A fortification of wheat flour: considerations and current recommendations","volume":"31","author":"Klemm","year":"2010","journal-title":"Food Nutr Bull"},{"issue":"88-103","key":"10.1093\/advances\/nmz100_bib14","article-title":"The research and implementation continuum of biofortified sweet potato and maize in Africa","volume":"1390","author":"Tanumihardjo","year":"2017","journal-title":"Ann N Y Acad Sci"},{"key":"10.1093\/advances\/nmz100_bib15","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.gfs.2017.01.009","article-title":"Improving nutrition through biofortification: a review of evidence from HarvestPlus, 2003 through 2016. What about?","volume":"12","author":"Bouis","year":"2017","journal-title":"Global Food Security"},{"issue":"12","key":"10.1093\/advances\/nmz100_bib16","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1017\/S0007114514000166","article-title":"A review of vitamin A equivalency of \u03b2-carotene in various food matrices for human consumption","volume":"111","author":"Van\u00a0Loo-Bouwman","year":"2014","journal-title":"Br J Nutr"},{"key":"10.1093\/advances\/nmz100_bib17","series-title":"Vitamin A supplementation","author":"World Health Organization","year":"2017"},{"key":"10.1093\/advances\/nmz100_bib18","series-title":"Guideline: vitamin A supplementation in infants and children 6\u201359 months of age","author":"World Health Organization","year":"2011"},{"key":"10.1093\/advances\/nmz100_bib19","series-title":"Coverage at a crossroads: new directions for VA supplementation programmes","author":"UNICEF","year":"2018"},{"key":"10.1093\/advances\/nmz100_bib20","doi-asserted-by":"crossref","unstructured":">20 Palmer A, Darnton-Hill I, West KW, Jr,. Vitamin A deficiency. In: de\u00a0Pee S, Taren D, Bloem MW, editors. Nutrition and health in a developing world. 3rd ed: Humana Press; 2017, p.; 181\u2013234.","DOI":"10.1007\/978-3-319-43739-2_9"},{"issue":"5","key":"10.1093\/advances\/nmz100_bib21","doi-asserted-by":"crossref","first-page":"798","DOI":"10.3945\/jn.117.247577","article-title":"Single high-dose vitamin A supplementation to neonatal piglets results in a transient dose response in extrahepatic organs and sustained increases in liver stores","volume":"147","author":"Gannon","year":"2017","journal-title":"J Nutr"},{"key":"10.1093\/advances\/nmz100_bib22","unstructured":">22 Engle-Stone R, Stewart CP, Vosti SA, Adams KP,. Preventative nutrition interventions. Tewdsbury, MA: Copenhagen Consensus Center; 2017."},{"issue":"11","key":"10.1093\/advances\/nmz100_bib23","doi-asserted-by":"crossref","first-page":"2194S","DOI":"10.3945\/jn.116.242271","article-title":"Estimating lives saved by achieving dietary micronutrient adequacy, with a focus on vitamin A intervention programs in Cameroon","volume":"147","author":"Engle-Stone","year":"2017","journal-title":"J Nutr"},{"key":"10.1093\/advances\/nmz100_bib24","doi-asserted-by":"crossref","first-page":"41","DOI":"10.2147\/NDS.S43523","article-title":"Prevention and control of micronutrient deficiencies in developing countries: current perspectives","volume":"6","author":"Faber","year":"2014","journal-title":"Nutr Diet Suppl"},{"key":"10.1093\/advances\/nmz100_bib25","series-title":"Effectiveness of vitamin A supplementation in the control of young child morbidity and mortality in developing countries","author":"Beaton","year":"1993"},{"issue":"12","key":"10.1093\/advances\/nmz100_bib26","first-page":"CD008524","article-title":"Vitamin A supplementation for preventing morbidity and mortality in children from 6 months to 5 years of age","volume":"8","author":"Imdad","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"10.1093\/advances\/nmz100_bib27","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1093\/ije\/dyv117","article-title":"An enigma: why vitamin A supplementation does not always reduce mortality even though vitamin A deficiency is associated with increased mortality","volume":"44","author":"Benn","year":"2015","journal-title":"Int J Epidemiol"},{"key":"10.1093\/advances\/nmz100_bib28","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1017\/S1368980012000560","article-title":"The use and interpretation of serum retinol distributions in evaluating the public health impact of vitamin A programmes","volume":"15","author":"Palmer","year":"2012","journal-title":"Public Health Nutr"},{"key":"10.1093\/advances\/nmz100_bib29","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1016\/S0140-6736(12)62125-4","article-title":"Vitamin A supplementation every 6 months with retinol in 1 million pre-school children in north India: DEVTA, a cluster-randomised trial","volume":"381","author":"Awasti","year":"2013","journal-title":"Lancet"},{"key":"10.1093\/advances\/nmz100_bib30","doi-asserted-by":"crossref","first-page":"e739","DOI":"10.1542\/peds.2014-0550","article-title":"High-dose vitamin A with vaccination after 6 months of age: a randomized trial","volume":"124","author":"Fisker","year":"2014","journal-title":"Pediatrics"},{"key":"10.1093\/advances\/nmz100_bib31","first-page":"CD008524","article-title":"Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age","volume":"3","author":"Imdad","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1093\/advances\/nmz100_bib32","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/ije\/dyu194","article-title":"Vitamin A policies need rethinking","volume":"44","author":"Mason","year":"2015","journal-title":"Int J Epidemiol"},{"issue":"6","key":"10.1093\/advances\/nmz100_bib33","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1007\/s12098-018-02851-x","article-title":"Does India need a universal high-dose vitamin A supplementation program?","volume":"86","author":"Greiner","year":"2019","journal-title":"Indian J Pediatr"},{"issue":"1","key":"10.1093\/advances\/nmz100_bib34","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1093\/ije\/dyu275","article-title":"Commentary: vitamin A policies need rethinking","volume":"44","author":"West","year":"2015","journal-title":"Int J Epidemiol"},{"key":"10.1093\/advances\/nmz100_bib35","unstructured":">35 Global Alliance for Vitamin A (GAVA). Internal briefing note on need for rethinking vitamin A policies [Internet]. Ottawa: GAVA; November 2, 2014; [cited July 22, 2019]. Available from: http:\/\/archive.wphna.org\/wp-content\/uploads\/2014\/12\/2014-11-GAVA-rebuttal-of-IJE-commentary-here.pdf,."},{"key":"10.1093\/advances\/nmz100_bib36","series-title":"Conditions for scaling back universal preschool vitamin A supplementation","author":"Global Alliance for Vitamin A (GAVA)","year":"2019"},{"issue":"9","key":"10.1093\/advances\/nmz100_bib37","doi-asserted-by":"crossref","first-page":"1816S","DOI":"10.3945\/jn.115.229708","article-title":"Biomarkers of Nutrition for Development (BOND)\u2014vitamin A review","volume":"146","author":"Tanumihardjo","year":"2016","journal-title":"J Nutr"},{"key":"10.1093\/advances\/nmz100_bib38","doi-asserted-by":"crossref","first-page":"658S","DOI":"10.3945\/ajcn.110.005777","article-title":"Vitamin A: biomarkers of nutrition for development","volume":"94","author":"Tanumihardjo","year":"2011","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/advances\/nmz100_bib39","unstructured":">39 Institute of Medicine. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium and zinc. Washington, DC: IOM; 2001."},{"issue":"6","key":"10.1093\/advances\/nmz100_bib40","doi-asserted-by":"crossref","first-page":"972","DOI":"10.3945\/jn.114.192245","article-title":"The acute phase response affected traditional measures of micronutrient status in rural Zambian children during a randomized, controlled feeding trial","volume":"144","author":"Bresnahan","year":"2014","journal-title":"J Nutr"},{"key":"10.1093\/advances\/nmz100_bib41","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1093\/jn\/126.2.451","article-title":"Vitamin A status of Indonesian children infected with Ascaris lumbricoides after dosing with vitamin A supplements and albendazole","volume":"126","author":"Tanumihardjo","year":"1996","journal-title":"J Nutr"},{"key":"10.1093\/advances\/nmz100_bib42","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1038\/sj.ejcn.1601953","article-title":"Vitamin A status and hemoglobin concentrations are improved in Indonesian children with vitamin A and deworming interventions","volume":"48","author":"Tanumihardjo","year":"2004","journal-title":"Eur J Clin Nutr"},{"key":"10.1093\/advances\/nmz100_bib43","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1093\/jn\/124.12.2477","article-title":"Vitamin A intake and status influence retinol balance, utilization and dynamics in rats","volume":"124","author":"Green","year":"1994","journal-title":"J Nutr"},{"key":"10.1093\/advances\/nmz100_bib44","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1024\/0300-9831\/a000042","article-title":"Provitamin A carotenoid bioavailability: what really matters?","volume":"80","author":"Tanumihardjo","year":"2010","journal-title":"Int J Vitam Nutr Res"},{"issue":"2","key":"10.1093\/advances\/nmz100_bib45","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1093\/ajcn\/72.2.455","article-title":"Bioconversion of plant carotenoids to vitamin A in Filipino school-aged children varies inversely with vitamin A status","volume":"72","author":"Ribaya-Mercado","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/advances\/nmz100_bib46","first-page":"373","article-title":"Food-based approaches for ensuring adequate vitamin A nutrition","volume":"7","author":"Tanumihardjo","year":"2008","journal-title":"Compr Rev Food Sci Food Safety"},{"issue":"1","key":"10.1093\/advances\/nmz100_bib47","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.abb.2010.06.032","article-title":"Molecular and dietary regulation of beta,beta-carotene 15,15'-monooxygenase 1 (BCMO1)","volume":"502","author":"Lietz","year":"2010","journal-title":"Arch Biochem Biophys"},{"issue":"2","key":"10.1093\/advances\/nmz100_bib48","doi-asserted-by":"crossref","first-page":"497","DOI":"10.3945\/ajcn.115.112383","article-title":"High provitamin A carotenoid serum concentrations, elevated retinyl esters, and saturated retinol-binding protein in Zambian preschool children are consistent with the presence of high liver vitamin A stores","volume":"102","author":"Mondloch","year":"2015","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/advances\/nmz100_bib49","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1038\/ejcn.2015.143","article-title":"Hypercarotenodermia in Zambia: which children turned orange during mango season?","volume":"69","author":"Tanumihardjo","year":"2015","journal-title":"Eur J Clin Nutr"},{"key":"10.1093\/advances\/nmz100_bib50","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/ajcn.81.2.427","article-title":"One-time vitamin A supplementation of lactating sows enhances hepatic retinol of offspring independent of dose size","volume":"81","author":"Valentine","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/advances\/nmz100_bib51","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1093\/ajcn\/86.4.1045","article-title":"One-time graded doses of vitamin A to weanling piglets enhance hepatic retinol but do not always prevent a deficient vitamin A status","volume":"86","author":"Surles","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/advances\/nmz100_bib52","doi-asserted-by":"crossref","first-page":"456","DOI":"10.30802\/AALAS-JAALAS-17-000148","article-title":"Vervets (Chlorocebus aethiops) consuming oil palm-derived carotenoids have higher hepatic vitamin A concentrations than controls","volume":"57","author":"Mondloch","year":"2018","journal-title":"J Am Assoc Lab Animal Sci"},{"key":"10.1093\/advances\/nmz100_bib53","series-title":"Vitamin A supplementation in children 6\u201359 months of age with severe acute malnutrition","author":"World Health Organization","year":"2018"},{"key":"10.1093\/advances\/nmz100_bib54","series-title":"Guideline: vitamin A supplementation in neonates","author":"World Health Organization","year":"2011"},{"key":"10.1093\/advances\/nmz100_bib55","series-title":"Vitamin A supplementation during pregnancy","author":"World Health Organization","year":"2018"},{"key":"10.1093\/advances\/nmz100_bib56","series-title":"Vitamin A supplementation in children with respiratory infections","author":"World Health Organization","year":"2018"},{"key":"10.1093\/advances\/nmz100_bib57","series-title":"Vitamin A supplementation in HIV-infected infants and children 6\u201359 months of age","author":"World Health Organization","year":"2018"},{"key":"10.1093\/advances\/nmz100_bib58","series-title":"Technical consultation on guidance to vitamin A supplementation programs for children 6\u201359 months of age","author":"Global Alliance for Vitamin A (GAVA)","year":"2012"},{"issue":"3","key":"10.1093\/advances\/nmz100_bib59","doi-asserted-by":"crossref","first-page":"190","DOI":"10.3390\/nu9030190","article-title":"Vitamin A supplementation programs and country-level evidence of vitamin A deficiency","volume":"9","author":"Wirth","year":"2017","journal-title":"Nutrients"},{"issue":"Suppl 1","key":"10.1093\/advances\/nmz100_bib60","doi-asserted-by":"crossref","first-page":"372S","DOI":"10.3945\/ajcn.116.142232","article-title":"Adjusting soluble transferrin receptor concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project","volume":"106","author":"Rohner","year":"2017","journal-title":"Am J Clin Nutr"},{"issue":"8","key":"10.1093\/advances\/nmz100_bib61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/nu10081100","article-title":"Approaches to assess vitamin A status in settings of inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project","volume":"10","author":"Larson","year":"2018","journal-title":"Nutrients"},{"issue":"6","key":"10.1093\/advances\/nmz100_bib62","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1136\/archdischild-2016-310631","article-title":"Vitamin A toxicity presenting as bone pain","volume":"102","author":"Baineni","year":"2017","journal-title":"Arch Dis Child"},{"key":"10.1093\/advances\/nmz100_bib63","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/nyas.13965","article-title":"Overlapping vitamin A interventions in the United States, Guatemala, Zambia, and South Africa: case studies: excessive intakes due to overlapping programs","volume":"1446","author":"Tanumihardjo","year":"2019","journal-title":"Ann NY Acad Sci"},{"issue":"6","key":"10.1093\/advances\/nmz100_bib64","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.3945\/ajcn.114.087379","article-title":"Biofortified orange maize is as efficacious as a vitamin A supplement in Zambian children even in the presence of high liver reserves of vitamin A: a community-based, randomized placebo-controlled trial","volume":"100","author":"Gannon","year":"2014","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/advances\/nmz100_bib65","doi-asserted-by":"crossref","first-page":"d5094","DOI":"10.1136\/bmj.d5094","article-title":"Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis","volume":"343","author":"Mayo-Wilson","year":"2011","journal-title":"BMJ"},{"issue":"Suppl. 2","key":"10.1093\/advances\/nmz100_bib66","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1177\/0379572116630481","article-title":"A changing landscape for VA programs: implications for optimal intervention packages, program monitoring, and safety","volume":"37","author":"Klemm","year":"2016","journal-title":"Food Nutr Bull"},{"key":"10.1093\/advances\/nmz100_bib67","series-title":"Technical consultation on guidance to vitamin A supplementation programs for children 6\u201359 months of age","author":"Global Alliance for Vitamin A (GAVA)","year":"2012"},{"key":"10.1093\/advances\/nmz100_bib68","series-title":"An\u00e1lisis de la situaci\u00f3n y tendencias de los micronutrientes clave en Guatemala, con un llamado a la acci\u00f3n desde las pol\u00edticas p\u00fablicas","author":"Mazariegos","year":"2016"},{"key":"10.1093\/advances\/nmz100_bib69","series-title":"Vitamin A sugar fortification in Central America: experience and lessons learned","author":"Mora","year":"2000"},{"issue":"1","key":"10.1093\/advances\/nmz100_bib70","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/heapol\/czs129","article-title":"Child health week in Zambia: costs, efficiency, coverage and a reassessment of need","volume":"29","author":"Fiedler","year":"2012","journal-title":"Health Pol Plan"},{"key":"10.1093\/advances\/nmz100_bib71","series-title":"Vitamin A fortification of sugar in Zambia 1998\u20132001","author":"Serlemitsos","year":"2001"},{"issue":"3","key":"10.1093\/advances\/nmz100_bib72","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1177\/0379572117707890","article-title":"Components of successful staple food fortification programs: lessons from Latin America","volume":"38","author":"Martorell","year":"2017","journal-title":"Food Nutr Bull"},{"issue":"1","key":"10.1093\/advances\/nmz100_bib73","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/ajcn\/34.1.41","article-title":"The effect of vitamin A fortification of sugar on the serum vitamin A levels of preschool Guatemalan children: a longitudinal evaluation","volume":"34","author":"Arroyave","year":"1981","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/advances\/nmz100_bib74","unstructured":">74 Dary O, Martinez C, Guamuch M,. Sugar fortification with vitamin A in Guatemala: the program\u2019s successes and pitfalls. In: Freire WB, editor. Nutrition and an active life from knowledge to action. Washington, DC: Pan American Health Organization; 2005, p. 43\u201359."},{"issue":"Suppl","key":"10.1093\/advances\/nmz100_bib75","doi-asserted-by":"crossref","first-page":"S63","DOI":"10.1177\/0379572116630480","article-title":"Assessing the safety of vitamin A delivered through large-scale intervention programs: workshop report on setting the research agenda","volume":"37","author":"Tanumihardjo","year":"2016","journal-title":"Food Nutr Bull"},{"key":"10.1093\/advances\/nmz100_bib76","unstructured":">76 Ministerio de Salud P\u00fablica y Asistencia Social (MSPAS). Encuesta nacional de micronutrientes 2009\u20132010 (ENMICRON 2009\u20132010). Guatemala; Ministerio de Salud P\u00fablica y Asistencia Social(MSPAS)\/Instituto Nacional de Estadistica (INE); 2012."},{"issue":"1","key":"10.1093\/advances\/nmz100_bib77","doi-asserted-by":"crossref","first-page":"124","DOI":"10.3945\/an.114.007443","article-title":"Fortification and health: challenges and opportunities","volume":"6","author":"Dwyer","year":"2015","journal-title":"Adv Nutr"},{"issue":"9 Suppl","key":"10.1093\/advances\/nmz100_bib78","doi-asserted-by":"crossref","first-page":"2927S","DOI":"10.1093\/jn\/132.9.2927S","article-title":"Food fortification","volume":"132","author":"Dary","year":"2002","journal-title":"J Nutr"},{"issue":"7 Pt 1","key":"10.1093\/advances\/nmz100_bib79","doi-asserted-by":"crossref","first-page":"S30","DOI":"10.1301\/002966402320285074","article-title":"Lessons learned with iron fortification in Central America","volume":"60","author":"Dary","year":"2002","journal-title":"Nutr Rev"},{"key":"10.1093\/advances\/nmz100_bib80","series-title":"Encuesta Nacional de Condiciones de Vida de Guatemala (ENCOVI 2006)","author":"Mench\u00fa","year":"2013"},{"issue":"6","key":"10.1093\/advances\/nmz100_bib81","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.3945\/ajcn.114.087379","article-title":"Biofortified orange maize is as efficacious as a vitamin A supplement in Zambian children even in the presence of high liver reserves of vitamin A: a community-based, randomized placebo-controlled trial","volume":"100","author":"Gannon","year":"2014","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/advances\/nmz100_bib82","doi-asserted-by":"crossref","unstructured":">82 Low JW,. Biofortifed crops with a visible trait: the example of orange-fleshed sweet potato in sub-Saharan Africa. In: Preedy VR, Srirajaskanthan R, Patel VB, editors. Handbook of food fortification and health. From concepts to public health applications, vol. 2. New York: Springer: Humana Press; 2013. p. 371\u201384.","DOI":"10.1007\/978-1-4614-7076-2_29"},{"issue":"4","key":"10.1093\/advances\/nmz100_bib83","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1177\/0379572117733841","article-title":"Poor performance of sugar fortification: retail sugar from one Zambian community does not meet statutory requirements for vitamin A fortification","volume":"38","author":"Greene","year":"2017","journal-title":"Food Nutr Bull"},{"key":"10.1093\/advances\/nmz100_bib84","doi-asserted-by":"crossref","first-page":"1015S","DOI":"10.3945\/jn.116.246157","article-title":"Coverage and utilization in food fortification programs: critical and neglected areas of evaluation","volume":"147","author":"Neufeld","year":"2017","journal-title":"J Nutr"},{"key":"10.1093\/advances\/nmz100_bib85","doi-asserted-by":"crossref","unstructured":">85 Gittelsohn J, Cristello A,. Sustaining a national MNP supplementation program: findings of the qualitative evaluation of the FORTIDOM pilot trial in Madagascar. Sight & Life Magazine. [Internet], 2014;28(2). Available from: https:\/\/www.dsm.com\/content\/dam\/dsm\/cworld\/en_US\/documents\/sal-magazine-2-2014.pdf,.","DOI":"10.52439\/ULLR2707"},{"issue":"3","key":"10.1093\/advances\/nmz100_bib86","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1177\/156482651103200315","article-title":"Understanding low usage of micronutrient powder in the Kakuma Refugee Camp, Kenya: findings from a qualitative study","volume":"32","author":"Kodish","year":"2011","journal-title":"Food Nutr Bull"},{"issue":"3","key":"10.1093\/advances\/nmz100_bib87","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1177\/156482651103200314","article-title":"Relationship of the availability of micronutrient powder with iron status and hemoglobin among women and children in the Kakuma Refugee Camp, Kenya","volume":"32","author":"Ndemwa","year":"2011","journal-title":"Food Nutr Bull"},{"key":"10.1093\/advances\/nmz100_bib88","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1748-5908-4-50","article-title":"Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science","volume":"4","author":"Damschroder","year":"2009","journal-title":"Implement Sci"},{"issue":"5","key":"10.1093\/advances\/nmz100_bib89","doi-asserted-by":"crossref","first-page":"981S","DOI":"10.3945\/jn.116.242842","article-title":"Assessing coverage of population-based and targeted fortification programs with the use of the Fortification Assessment Coverage Toolkit (FACT): background, toolkit development, and supplement overview","volume":"147","author":"Friesen","year":"2017","journal-title":"J Nutr"},{"key":"10.1093\/advances\/nmz100_bib90","series-title":"Vitamin A supplementation. Full set of recommendations","author":"World Health Organization","year":"2011"},{"key":"10.1093\/advances\/nmz100_bib91","doi-asserted-by":"crossref","unstructured":">91 Coughlin MM, Beck AS, Bankamp B,. Perspective on global measles epidemiology and control and the role of novel vaccination strategies. Viruses. [Internet], 2017;9(1):11. doi:10.3390\/v9010011 RPVPJ.","DOI":"10.3390\/v9010011"},{"issue":"9071","key":"10.1093\/advances\/nmz100_bib92","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0140-6736(96)12019-5","article-title":"Randomized trial of effect of vitamin A supplementation on antibody response to measles vaccine in Guinea-Bissau, west Africa","volume":"350","author":"Benn","year":"1997","journal-title":"Lancet"},{"issue":"3","key":"10.1093\/advances\/nmz100_bib93","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1177\/0379572116646280","article-title":"Safety and mortality benefits of delivering vitamin A supplementation at 6 months of age in sub-Saharan Africa","volume":"37","author":"Kupka","year":"2016","journal-title":"Food Nutr Bull"},{"issue":"1","key":"10.1093\/advances\/nmz100_bib94","first-page":"B4378","article-title":"Combining vitamin A and vaccines: convenience or conflict?","volume":"59","author":"Benn","year":"2012","journal-title":"Dan Med J"},{"issue":"34","key":"10.1093\/advances\/nmz100_bib95","doi-asserted-by":"crossref","first-page":"4304","DOI":"10.1016\/j.vaccine.2008.06.007","article-title":"Response to \u201cConflicting evidence for neonatal vitamin A supplementation (letter)\u201d by Benn et al","volume":"26","author":"Bhutta","year":"2008","journal-title":"Vaccine"},{"key":"10.1093\/advances\/nmz100_bib96","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.copbio.2016.10.006","article-title":"The intersection of climate\/environment, food, nutrition and health: crisis and opportunity","volume":"44","author":"Raiten","year":"2016","journal-title":"Curr Opinion Biotech"}],"container-title":["Advances in Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2161831322002502?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2161831322002502?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/advances\/advance-article-pdf\/doi\/10.1093\/advances\/nmz100\/30155582\/nmz100.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/advances\/advance-article-pdf\/doi\/10.1093\/advances\/nmz100\/30155582\/nmz100.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:59:45Z","timestamp":1761872385000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2161831322002502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":96,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["S2161831322002502"],"URL":"https:\/\/doi.org\/10.1093\/advances\/nmz100","relation":{},"ISSN":["2161-8313"],"issn-type":[{"value":"2161-8313","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Perspective: Integration to Implementation (I-to-I) and the Micronutrient Forum\u2014Addressing the Safety and Effectiveness of Vitamin A Supplementation","name":"articletitle","label":"Article Title"},{"value":"Advances in Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/advances\/nmz100","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 American Society for Nutrition","name":"copyright","label":"Copyright"}]}}