{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T16:12:40Z","timestamp":1784650360977,"version":"3.55.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>As people age they are at increased risk of cardiovascular disease, the leading cause of mortality and morbidity worldwide. Understanding cardiovascular ageing is essential to preserving healthy ageing and preventing serious health outcomes. This collection of papers published in Age and Ageing since 2011 cover key themes in cardiovascular ageing, with a separate collection on stroke and atrial fibrillation planned.<\/jats:p>\n               <jats:p>Treating high blood pressure remains important as people age and reduces strokes and heart attacks. That said, a more personalised approach to blood pressure may be even more important as people age to lower blood pressure to tight targets where appropriate but avoid overtreatment in vulnerable groups. As people age, more people experience blood pressure drops on standing (orthostatic hypotension), particularly as they become frail. This can predispose them to falls. The papers in this collection provide an insight into blood pressure and orthostatic hypotension. They highlight areas for further research to understand blood pressure changes and management in the ageing population.<\/jats:p>\n               <jats:p>Inpatient clinical care of older people with heart attacks differs from younger people in UK national audit data. People aged over 80 had improved outcomes in survival after heart attack over time, but had lower rates of specialist input from cardiology compared with younger people. This may partly reflect different clinical presentations, with heart attacks occurring in the context of other health conditions, frailty and multimorbidity. The care and outcomes of acute and chronic cardiovascular disease are impacted by the frailty and health status of an individual at baseline.<\/jats:p>\n               <jats:p>The research included in this collection reinforces the wide variations in the ageing population and the necessity to focus on the individual needs and priorities, and provide a person-centred multidisciplinary approach to care.<\/jats:p>","DOI":"10.1093\/ageing\/afac179","type":"journal-article","created":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:11:05Z","timestamp":1659917465000},"source":"Crossref","is-referenced-by-count":22,"title":["Age and ageing cardiovascular collection: blood pressure, coronary heart disease and heart failure"],"prefix":"10.1093","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3794-7065","authenticated-orcid":false,"given":"Jane A H","family":"Masoli","sequence":"first","affiliation":[{"name":"Healthcare for Older People, Royal Devon University Healthcare NHS Foundation Trust , Exeter , UK"},{"name":"Institute of Biomedical and Clinical Science, University of Exeter , Exeter UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekow","family":"Mensah","sequence":"additional","affiliation":[{"name":"Department of Elderly Care and Stroke Medicine, Brighton and Sussex University Hospitals Trust , Brighton , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chakravarthi","family":"Rajkumar","sequence":"additional","affiliation":[{"name":"Department of Elderly Care and Stroke Medicine, Brighton and Sussex University Hospitals Trust , Brighton , UK"},{"name":"Department of Medicine, Brighton and Sussex Medical School , Brighton , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,8,8]]},"reference":[{"key":"2022090221091938300_ref1","doi-asserted-by":"crossref","first-page":"2982","DOI":"10.1016\/j.jacc.2020.11.010","article-title":"Global burden of cardiovascular diseases and risk factors, 1990-2019: update from the GBD 2019 study","volume":"76","author":"Roth","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"2022090221091938300_ref2","article-title":"Hypertension management in older patients\u2014are the guideline blood pressure targets appropriate?","author":"Masoli","year":"2021","journal-title":"Age Ageing"},{"key":"2022090221091938300_ref3","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1093\/ageing\/afv141","article-title":"Blood pressure and 10-year mortality risk in the Milan Geriatrics 75+ Cohort Study: role of functional and cognitive status","volume":"44","author":"Ogliari","year":"2015","journal-title":"Age Ageing"},{"key":"2022090221091938300_ref4","doi-asserted-by":"crossref","DOI":"10.1093\/ageing\/afaa028","article-title":"Blood pressure in frail older adults: associations with cardiovascular outcomes and all-cause mortality","author":"Masoli","year":"2020","journal-title":"Age 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Open"},{"key":"2022090221091938300_ref8","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1093\/ageing\/afaa077","article-title":"Relationship between sarcopenia and orthostatic hypotension","volume":"49","author":"Soysal","year":"2020","journal-title":"Age Ageing"},{"key":"2022090221091938300_ref9","first-page":"439","article-title":"A prospective study of the association between orthostatic hypotension and falls: definition matters","volume":"46","author":"McDonald","year":"2017","journal-title":"Age Ageing"},{"key":"2022090221091938300_ref10","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/ageing\/afz173","article-title":"Combination non-pharmacologic intervention for orthostatic hypotension in older people: a phase 2 study","volume":"49","author":"Frith","year":"2020","journal-title":"Age Ageing"},{"key":"2022090221091938300_ref11","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.1938","article-title":"Twenty-year trends in outcomes for older adults with acute myocardial infarction in the United States","volume":"2","author":"Krumholz","year":"2019","journal-title":"JAMA Netw Open"},{"key":"2022090221091938300_ref12","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s12872-017-0482-9","article-title":"Mortality and morbidity trends after the first year in survivors of acute myocardial infarction: a systematic review","volume":"17","author":"Johansson","year":"2017","journal-title":"BMC Cardiovasc Disord"},{"key":"2022090221091938300_ref13","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1093\/ageing\/aft201","article-title":"Age-dependent improvements in survival after hospitalisation with acute myocardial infarction: an analysis of the Myocardial Ischemia National Audit Project (MINAP)","volume":"43","author":"Alabas","year":"2014","journal-title":"Age 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