{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T10:55:17Z","timestamp":1779101717199,"version":"3.51.4"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2022,12,26]],"date-time":"2022-12-26T00:00:00Z","timestamp":1672012800000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>objective indicators of sleep and mental health problems in family caregivers have rarely been reported.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>to study the use of prescription benzodiazepines and related drugs (BZDRD) in Finnish family caregivers and matched controls.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>prospective follow-up in 2012\u201317.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Setting<\/jats:title>\n                  <jats:p>nationwide register-linkage study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Subjects<\/jats:title>\n                  <jats:p>all individuals who received family caregiver\u2019s allowance in Finland in 2012 (N\u2009=\u200942,256; mean age 67\u00a0years; 71% women) and controls matched for age, sex and municipality of residence (N\u2009=\u200983,618).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>information on purchases of prescription BZDRD, including the number of defined daily doses (DDDs), between 2012 and 2017 was obtained from the Dispensations Reimbursable under the National Health Insurance Scheme register. Background information was obtained from national registers.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>more caregivers than controls used BZDRD, both among women (users per 100 person-years: 17.2 versus 15.2, P\u2009&amp;lt;\u20090.001) and men (14.6 versus 11.8, P\u2009&amp;lt;\u20090.001). These differences were largely explained by hypnotic BZDRD use. There were also more long-term BZDRD users per 100 person-years among caregivers than controls, both among women (5.0 versus 4.3, P\u2009=\u20090.001) and men (5.3 versus 3.8, P\u2009&amp;lt;\u20090.001). Use of hypnotic BZDRD in number of DDDs was higher in caregivers than in controls, particularly among men above 50\u00a0years. Caregivers used more anxiolytic BZDRD than controls from middle age to 75\u00a0years but less in the oldest age groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>higher level of BZDRD use among caregivers indicates that caregivers have more sleep and mental health problems than non-caregivers. Adequate treatment of these problems and support for caregiving should be ensured for caregivers.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ageing\/afac279","type":"journal-article","created":{"date-parts":[[2022,12,26]],"date-time":"2022-12-26T16:48:53Z","timestamp":1672073333000},"source":"Crossref","is-referenced-by-count":2,"title":["Use of prescription benzodiazepines and related drugs in family caregivers: a nation-wide register-based study"],"prefix":"10.1093","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0885-2788","authenticated-orcid":false,"given":"Tuija M","family":"Mikkola","sequence":"first","affiliation":[{"name":"Folkh\u00e4lsan Research Center , Helsinki, Finland"},{"name":"University of Helsinki Clinicum, Faculty of Medicine, , Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minna","family":"M\u00e4nty","sequence":"additional","affiliation":[{"name":"Unit of Strategy and Research, City of Vantaa , Vantaa, Finland"},{"name":"University of Helsinki Department of Public Health, , Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannu","family":"Kautiainen","sequence":"additional","affiliation":[{"name":"Folkh\u00e4lsan Research Center , Helsinki, Finland"},{"name":"Kuopio University Hospital Primary Health Care Unit, , Kuopio, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikaela B","family":"von Bonsdorff","sequence":"additional","affiliation":[{"name":"Folkh\u00e4lsan Research Center , Helsinki, Finland"},{"name":"University of Jyv\u00e4skyl\u00e4 Gerontology Research Centre and Faculty of Sport and Health Sciences, , Jyv\u00e4skyl\u00e4, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannu","family":"Koponen","sequence":"additional","affiliation":[{"name":"University of Helsinki and Helsinki University Hospital Department of Psychiatry, , Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5019-6230","authenticated-orcid":false,"given":"Teppo","family":"Kr\u00f6ger","sequence":"additional","affiliation":[{"name":"University of Jyv\u00e4skyl\u00e4 Department of Social Sciences and Philosophy, , Jyv\u00e4skyl\u00e4, Finland"},{"name":"Western Norway University of Applied Sciences Centre for Care Research West, , Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan G","family":"Eriksson","sequence":"additional","affiliation":[{"name":"Folkh\u00e4lsan Research Center , Helsinki, Finland"},{"name":"Singapore Institute for Clinical Sciences , Agency for Science, Technology, and Research, Singapore, Singapore"},{"name":"National University of Singapore Department of Obstetrics & Gynaecology and Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, , Singapore, Singapore"},{"name":"University of Helsinki Department of General Practice and Primary Health Care, , Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,12,19]]},"reference":[{"key":"2022122616011599600_ref1","doi-asserted-by":"crossref","first-page":"371.e11","DOI":"10.1016\/j.jamda.2017.12.098","article-title":"Fall-risk-increasing drugs: a systematic review and meta-analysis: II. 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