{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:46:46Z","timestamp":1787240806330,"version":"build-2736575974"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T00:00:00Z","timestamp":1685318400000},"content-version":"vor","delay-in-days":28,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000377","name":"Dunhill Medical Trust","doi-asserted-by":"publisher","award":["RTF107\/0117"],"award-info":[{"award-number":["RTF107\/0117"]}],"id":[{"id":"10.13039\/501100000377","id-type":"DOI","asserted-by":"publisher"}]},{"name":"British Geriatrics Society Bulpitt Undergraduate Scholarship"},{"name":"Royal Society via a Sir Henry Dale Fellowship","award":["211182\/Z\/18\/Z"],"award-info":[{"award-number":["211182\/Z\/18\/Z"]}]},{"DOI":"10.13039\/501100013373","name":"NIHR Oxford Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013373","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>it is not known if clinical practice reflects guideline recommendations for the management of hypertension in older people and whether guideline adherence varies according to overall health status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>to describe the proportion of older people attaining National Institute for Health and Care Excellence (NICE) guideline blood pressure targets within 1 year of hypertension diagnosis and determine predictors of target attainment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>a nationwide cohort study of Welsh primary care data from the Secure Anonymised Information Linkage databank including patients aged \u226565\u00a0years newly diagnosed with hypertension between 1st June 2011 and 1st June 2016. The primary outcome was attainment of NICE guideline blood pressure targets as measured by the latest blood pressure recording up to 1\u00a0year after diagnosis. Predictors of target attainment were investigated using logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>there were 26,392 patients (55% women, median age 71 [IQR 68\u201377] years) included, of which 13,939 (52.8%) attained a target blood pressure within a median follow-up of 9 months. Success in attaining target blood pressure was associated with a history of atrial fibrillation (OR 1.26, 95% CI 1.11, 1.43), heart failure (OR 1.25, 95% CI 1.06, 1.49) and myocardial infarction (OR 1.20, 95% CI 1.10, 1.32), all compared to no history of each, respectively. Care home residence, the severity of frailty, and increasing co-morbidity were not associated with target attainment following adjustment for confounder variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>blood pressure remains insufficiently controlled 1 year after diagnosis in nearly half of older people with newly diagnosed hypertension, but target attainment appears unrelated to baseline frailty, multi-morbidity or care home residence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ageing\/afad077","type":"journal-article","created":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T20:59:23Z","timestamp":1684961963000},"source":"Crossref","is-referenced-by-count":2,"title":["Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study"],"prefix":"10.1093","volume":"52","author":[{"given":"Oliver","family":"Todd","sequence":"first","affiliation":[{"name":"Academic Unit for Ageing and Stroke Research , University of Leeds, Leeds, England LS2 9LH , UK"},{"name":"Bradford Institute for Health Research , Bradford Teaching Hospitals NHS Trust, Bradford, England BD9 6RJ , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Johnson","sequence":"additional","affiliation":[{"name":"School of Medicine , University of Leeds, Leeds, England, LS2 9LH , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Wilkinson","sequence":"additional","affiliation":[{"name":"Hull York Medical School, University of York , York, England YO10 5DD , UK"},{"name":"Academic Cardiovascular Unit, South Tees NHS Foundation Trust , Middlesbrough, England TS4 3BY , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"Hollinghurst","sequence":"additional","affiliation":[{"name":"Health Data Research UK (HDR-UK) , University of Swansea, Swansea, Wales SA2 8PP , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatendashe B","family":"Dondo","sequence":"additional","affiliation":[{"name":"Leeds Institute for Cardiovascular and Metabolic Medicine , University of Leeds, Leeds, England LS2 9LH , UK"},{"name":"Leeds Institute for Data Analytics , University of Leeds, Leeds, England LS2 9LH , UK"},{"name":"Department of Cardiology , Leeds Teaching Hospitals NHS Trust, Leeds, England LS2 9LH , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad E","family":"Yadegarfar","sequence":"additional","affiliation":[{"name":"School of Life Course & Population Sciences , King\u2019s College London, London, England WC2R 2LS , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James P","family":"Sheppard","sequence":"additional","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences, University of Oxford , Oxford, England OX2 6GG , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J","family":"McManus","sequence":"additional","affiliation":[{"name":"Nuffield Department of Primary Care Health Sciences, University of Oxford , Oxford, England OX2 6GG , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris P","family":"Gale","sequence":"additional","affiliation":[{"name":"Leeds Institute for Cardiovascular and Metabolic Medicine , University of Leeds, Leeds, England LS2 9LH , UK"},{"name":"Leeds Institute for Data Analytics , University of Leeds, Leeds, England LS2 9LH , UK"},{"name":"Department of Cardiology , Leeds Teaching Hospitals NHS Trust, Leeds, England LS2 9LH , 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