{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:26:33Z","timestamp":1792009593065,"version":"4.4.0"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Chinese National Science & Technology Pillar Program","award":["2020YFC2005600"],"award-info":[{"award-number":["2020YFC2005600"]}]},{"name":"Sichuan Science and Technology Program","award":["2022YFS0295"],"award-info":[{"award-number":["2022YFS0295"]}]},{"name":"Sichuan Science and Technology Program","award":["2022YFG0205"],"award-info":[{"award-number":["2022YFG0205"]}]},{"DOI":"10.13039\/501100013365","name":"West China Hospital, Sichuan University","doi-asserted-by":"publisher","award":["ZYJC21005"],"award-info":[{"award-number":["ZYJC21005"]}],"id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Health Research of Cadres in Sichuan Province","award":["SCR2022-101"],"award-info":[{"award-number":["SCR2022-101"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sarcopenia is an important prognostic factor, but its optimal screening methods remain challenging. Several new indices developed based on serum creatinine (Cr) and cystatin C (CysC) have been proposed to be diagnostic biomarkers for sarcopenia screening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This review aimed to evaluate the diagnostic accuracy of serum Cr- and CysC-based indices for sarcopenia diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We systematically searched MEDLINE, EMBASE, SCIE and SCOPUS from inception to 2 April 2023. Methodological quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. A bivariate random-effects model was used to synthesise the pooled sensitivity, specificity and area under the curves of the summary receiver operating characteristic (SROC-AUC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We retrieved 936 publications and included 16 studies with 5,566 participants (mean age ranged: 51.0\u201378.4\u00a0years, 50.2% men). The prevalence of sarcopenia ranged from 7.8 to 69.5%. All included studies presented a moderate to high risk of bias. The serum Cr- and CysC-based indices showed moderate diagnostic accuracy for sarcopenia (pooled sensitivity: 0.67, 95% CI 0.57\u20130.75; pooled specificity: 076, 95% CI 0.67\u20130.83; pooled SROC-AUC: 0.78, 95% CI 0.74\u20130.81). The Cr\/CysC ratio is the most widely studied index, followed by the Cr\u2009\u00d7\u2009eGFRcys index. Overall, both indicators had satisfactory and comparable performance in screening sarcopenia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Serum Cr- and CysC-based indices showed moderate diagnostic accuracy for sarcopenia. The most studied indices\u2014the Cr\/CysC ratio and Cr\u2009\u00d7\u2009eGFRcys index\u2014had comparable diagnostic accuracy for evaluating sarcopenia and may serve as surrogate markers for sarcopenia. However, further validation is required to verify these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ageing\/afad252","type":"journal-article","created":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T02:58:12Z","timestamp":1703300292000},"source":"Crossref","is-referenced-by-count":46,"title":["Diagnostic test accuracy of serum creatinine and cystatin C-based index for sarcopenia: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"53","author":[{"given":"Taiping","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University , Chengdu 610041, Sichuan , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University , Chengdu 610041, Sichuan , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotao","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Jiangyou 903 Hospital , Mianyang, Sichuan , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Sichuan University Library , Chengdu, Sichuan , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University , Chengdu 610041, Sichuan , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quhong","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University , Chengdu 610041, Sichuan , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangping","family":"Tu","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University , Chengdu 610041, Sichuan , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanli","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University , Chengdu 610041, Sichuan , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University , Chengdu 610041, Sichuan , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jirong","family":"Yue","sequence":"additional","affiliation":[{"name":"Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University , Chengdu 610041, Sichuan , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2256-0653","authenticated-orcid":false,"given":"Chenkai","family":"Wu","sequence":"additional","affiliation":[{"name":"Global Health Research Center, Duke Kunshan University , Kunshan, Jiangsu Province , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,1,20]]},"reference":[{"key":"2024020213493158400_ref1","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/ageing\/afz046","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"2024020213493158400_ref2","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","article-title":"Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment","volume":"21","author":"Chen","year":"2020","journal-title":"J Am Med Dir Assoc"},{"key":"2024020213493158400_ref3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0169548","article-title":"Health outcomes of sarcopenia: a systematic review and meta-analysis","volume":"12","author":"Beaudart","year":"2017","journal-title":"PloS One"},{"key":"2024020213493158400_ref4","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.maturitas.2018.11.003","article-title":"The health economics burden of sarcopenia: a systematic review","volume":"119","author":"Bruy\u00e8re","year":"2019","journal-title":"Maturitas"},{"key":"2024020213493158400_ref5","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1532-5415.2004.52014.x","article-title":"The healthcare costs of sarcopenia in the United States","volume":"52","author":"Janssen","year":"2004","journal-title":"J Am Geriatr Soc"},{"key":"2024020213493158400_ref6","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1093\/gerona\/glu010","article-title":"The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates","volume":"69","author":"Studenski","year":"2014","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2024020213493158400_ref7","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s13539-012-0079-1","article-title":"Serum creatinine as a marker of muscle mass in chronic kidney disease: results of a cross-sectional study and review of literature","volume":"4","author":"Patel","year":"2013","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"2024020213493158400_ref8","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1080\/00365519950185076","article-title":"Relationships among serum cystatin C, serum creatinine, lean tissue mass and glomerular filtration rate in healthy adults","volume":"59","author":"Vinge","year":"1999","journal-title":"Scand J Clin Lab Invest"},{"key":"2024020213493158400_ref9","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1093\/ckj\/sfad086","article-title":"Muscle mass, creatinine, cystatin C and selective glomerular hypofiltration syndromes","volume":"16","author":"Malmgren","year":"2023","journal-title":"Clin Kidney J"},{"key":"2024020213493158400_ref10","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/imj.1959.8.3.218","article-title":"Plasma creatinine level and creatinine clearance as tests of renal function","volume":"8","author":"Edwards","year":"1959","journal-title":"Australas Ann Med"},{"key":"2024020213493158400_ref11","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1080\/00365513.2022.2031279","article-title":"Cystatin C-based equations for estimating glomerular filtration rate do not require race or sex coefficients","volume":"82","author":"Ottosson Frost","year":"2022","journal-title":"Scand J Clin Lab Invest"},{"key":"2024020213493158400_ref12","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.0954-6820.1985.tb08880.x","article-title":"Serum concentration of cystatin C, factor D and beta 2-microglobulin as a measure of glomerular filtration rate","volume":"218","author":"Grubb","year":"1985","journal-title":"Acta Med Scand"},{"key":"2024020213493158400_ref13","doi-asserted-by":"crossref","first-page":"333","DOI":"10.3109\/00365513.2015.1025427","article-title":"Reduction in glomerular pore size is not restricted to pregnant women. Evidence for a new syndrome: 'Shrunken pore syndrome'","volume":"75","author":"Grubb","year":"2015","journal-title":"Scand J Clin Lab Invest"},{"key":"2024020213493158400_ref14","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1080\/00365513.2020.1759139","article-title":"Shrunken pore syndrome and mortality: a cohort study of patients with measured GFR and known comorbidities","volume":"80","author":"\u00c5kesson","year":"2020","journal-title":"Scand J Clin Lab Invest"},{"key":"2024020213493158400_ref15","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/joim.13589","article-title":"The complexity of kidney disease and diagnosing it - cystatin C, selective glomerular hypofiltration syndromes and proteome regulation","volume":"293","author":"Malmgren","year":"2023","journal-title":"J Intern Med"},{"key":"2024020213493158400_ref16","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1001\/jama.2017.19163","article-title":"Preferred reporting items for a systematic review and meta-analysis of diagnostic test accuracy studies: the PRISMA-DTA statement","volume":"319","author":"McInnes","year":"2018","journal-title":"JAMA"},{"key":"2024020213493158400_ref17","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jamda.2013.11.025","article-title":"Sarcopenia in Asia: consensus report of the Asian Working Group for Sarcopenia","volume":"15","author":"Chen","year":"2014","journal-title":"J Am Med Dir Assoc"},{"key":"2024020213493158400_ref18","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older People","volume":"39","author":"Cruz-Jentoft","year":"2010","journal-title":"Age Ageing"},{"key":"2024020213493158400_ref19","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1002\/jcsm.12977","article-title":"Serum creatinine and cystatin C-based diagnostic indices for sarcopenia in advanced non-small cell lung cancer","volume":"13","author":"Tang","year":"2022","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"2024020213493158400_ref20","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2020.111032","article-title":"A new index based on serum creatinine and cystatin C is useful for assessing sarcopenia in patients with advanced cancer","volume":"82","author":"Fu","year":"2021","journal-title":"Nutrition"},{"key":"2024020213493158400_ref21","doi-asserted-by":"crossref","first-page":"529","DOI":"10.7326\/0003-4819-155-8-201110180-00009","article-title":"QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies","volume":"155","author":"Whiting","year":"2011","journal-title":"Ann Intern Med"},{"key":"2024020213493158400_ref22","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.3348\/kjr.2015.16.6.1175","article-title":"Systematic review and meta-analysis of studies evaluating diagnostic test accuracy: a practical review for clinical researchers-Part I. General Guidance and Tips","volume":"16","author":"Kim","year":"2015","journal-title":"Korean J Radiol"},{"key":"2024020213493158400_ref23","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.jclinepi.2005.01.016","article-title":"The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed","volume":"58","author":"Deeks","year":"2005","journal-title":"J Clin Epidemiol"},{"key":"2024020213493158400_ref24","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1093\/ije\/31.1.88","article-title":"Asymmetric funnel plots and publication bias in meta-analyses of diagnostic accuracy","volume":"31","author":"Song","year":"2002","journal-title":"Int J Epidemiol"},{"key":"2024020213493158400_ref25","doi-asserted-by":"crossref","first-page":"902.e21","DOI":"10.1016\/j.jamda.2021.07.029","article-title":"Estimation of muscle mass using creatinine\/cystatin C ratio in Japanese community-dwelling older people","volume":"23","author":"Kusunoki","year":"2022","journal-title":"J Am Med Dir Assoc"},{"key":"2024020213493158400_ref26","doi-asserted-by":"crossref","first-page":"580","DOI":"10.23876\/j.krcp.21.214","article-title":"Serum cystatin C to creatinine ratio is associated with sarcopenia in non-dialysis-dependent chronic kidney disease","volume":"41","author":"An","year":"2022","journal-title":"Kidney Res Clin Pract"},{"key":"2024020213493158400_ref27","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1186\/s12890-022-02000-3","article-title":"Serum creatinine\/cystatin C ratio is a surrogate marker for sarcopenia in patients with idiopathic pulmonary fibrosis","volume":"22","author":"Fujita","year":"2022","journal-title":"BMC Pulm Med"},{"key":"2024020213493158400_ref28","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/j.clnu.2020.08.010","article-title":"Serum creatinine\/cystatin C ratio as a surrogate marker for sarcopenia in patients with chronic obstructive pulmonary disease","volume":"40","author":"Hirai","year":"2021","journal-title":"Clin Nutr"},{"key":"2024020213493158400_ref29","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s10157-020-01981-x","article-title":"Relationships between cystatin C- and creatinine-based eGFR in Japanese rural community- dwelling older adults with sarcopenia","volume":"25","author":"Kusunoki","year":"2021","journal-title":"Clin Exp Nephrol"},{"key":"2024020213493158400_ref30","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.828880","article-title":"A novel application of serum creatinine and cystatin C to predict sarcopenia in advanced CKD","volume":"9","author":"Lin","year":"2022","journal-title":"Front Nutr"},{"key":"2024020213493158400_ref31","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1111\/cen.14568","article-title":"Prevalence of sarcopenia after remission of hypercortisolism and its impact on HRQoL","volume":"95","author":"Martel-Duguech","year":"2021","journal-title":"Clin Endocrinol (Oxf)"},{"key":"2024020213493158400_ref32","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.diabres.2018.02.025","article-title":"Decreased the creatinine to cystatin C ratio is a surrogate marker of sarcopenia in patients with type 2 diabetes","volume":"139","author":"Osaka","year":"2018","journal-title":"Diabetes Res Clin Pract"},{"key":"2024020213493158400_ref33","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s41999-019-00197-x","article-title":"Serum creatinine and cystatin C-based index can be a screening biomarker for sarcopenia in older population","volume":"10","author":"Singhal","year":"2019","journal-title":"Eur Geriatr Med"},{"key":"2024020213493158400_ref34","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s12876-022-02093-4","article-title":"Serum creatinine\/cystatin C ratio as a surrogate marker for sarcopenia in patients with gastric cancer","volume":"22","author":"Sun","year":"2022","journal-title":"BMC Gastroenterol"},{"key":"2024020213493158400_ref35","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.clnesp.2021.12.027","article-title":"Assessment of sarcopenia and malnutrition using estimated GFR ratio (eGFRcys\/eGFR) in hospitalised adult patients","volume":"48","author":"Yoshida","year":"2022","journal-title":"Clin Nutr ESPEN"},{"key":"2024020213493158400_ref36","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.clnesp.2022.07.010","article-title":"Relationship between the creatinine\/cystatin C ratio and muscle mass measured by CT-scan in cancer patients","volume":"51","author":"Tlemsani","year":"2022","journal-title":"Clin Nutr ESPEN"},{"key":"2024020213493158400_ref37","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.963265","article-title":"Serum creatinine\/cystatin C ratio is a systemic marker of sarcopenia in patients with gastrointestinal stromal tumours","volume":"9","author":"Ding","year":"2022","journal-title":"Front Nutr"},{"key":"2024020213493158400_ref38","article-title":"A new index based on serum creatinine and cystatin C can predict the risks of sarcopenia, falls and fractures in old patients with low bone mineral density","volume":"14","author":"Ge","journal-title":"Nutrients"},{"key":"2024020213493158400_ref39","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1016\/j.jamda.2021.05.011","article-title":"Reliability and concurrent validity of the SARC-F and its modified versions: a systematic review and meta-analysis","volume":"22","author":"Voelker","year":"2021","journal-title":"J Am Med Dir Assoc"},{"key":"2024020213493158400_ref40","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.jamda.2018.04.001","article-title":"SARC-F for screening of sarcopenia among older adults: a meta-analysis of screening test accuracy","volume":"19","author":"Ida","year":"2018","journal-title":"J Am Med Dir Assoc"},{"key":"2024020213493158400_ref41","article-title":"Ultrasound imaging for the diagnosis and evaluation of sarcopenia: an umbrella review","volume":"12","author":"Wang","journal-title":"Life"},{"key":"2024020213493158400_ref42","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1002\/jcsm.12210","article-title":"The reliability and validity of ultrasound to quantify muscles in older adults: a systematic review","volume":"8","author":"Nijholt","year":"2017","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"2024020213493158400_ref43","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1177\/0269215511434994","article-title":"Reliability of real-time ultrasound for measuring skeletal muscle size in human limbs in vivo: a systematic review","volume":"26","author":"English","year":"2012","journal-title":"Clin Rehabil"},{"key":"2024020213493158400_ref44","article-title":"Ultrasound-derived muscle assessment system for older adults: a promising muscle mass estimation tool","volume":"51","author":"Tang","journal-title":"Age Ageing"},{"key":"2024020213493158400_ref45","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/jcsm.13149","article-title":"Diagnostic test accuracy of ultrasound for sarcopenia diagnosis: a systematic review and meta-analysis","volume":"14","author":"Fu","year":"2023","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"2024020213493158400_ref46","doi-asserted-by":"crossref","DOI":"10.1093\/pcmedi\/pbac013","article-title":"Precision intervention for sarcopenia","volume":"5","author":"Liu","year":"2022","journal-title":"Precis Clin Med"},{"key":"2024020213493158400_ref47","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1097\/CCM.0000000000002013","article-title":"Evaluating muscle mass by using markers of kidney function: development of the sarcopenia index","volume":"45","author":"Kashani","year":"2017","journal-title":"Crit Care Med"},{"key":"2024020213493158400_ref48","article-title":"Serum creatinine\/cystatin C ratio as a muscle mass evaluating tool and prognostic indicator for hospitalized patients: a meta-analysis","volume":"9","author":"Zheng","year":"2022","journal-title":"Front Med (Lausanne)"},{"key":"2024020213493158400_ref49","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"key":"2024020213493158400_ref50","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1056\/NEJMoa1114248","article-title":"Estimating glomerular filtration rate from serum creatinine and cystatin C","volume":"367","author":"Inker","year":"2012","journal-title":"N Engl J Med"}],"container-title":["Age and Ageing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ageing\/article-pdf\/53\/1\/afad252\/56545788\/afad252.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ageing\/article-pdf\/53\/1\/afad252\/56545788\/afad252.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T09:33:29Z","timestamp":1706866409000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ageing\/article\/doi\/10.1093\/ageing\/afad252\/7584448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,1]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1,2]]}},"URL":"https:\/\/doi.org\/10.1093\/ageing\/afad252","relation":{},"ISSN":["0002-0729","1468-2834"],"issn-type":[{"value":"0002-0729","type":"print"},{"value":"1468-2834","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,1,1]]},"published":{"date-parts":[[2024,1,1]]},"article-number":"afad252"}}