{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:12:45Z","timestamp":1787317965950,"version":"build-2736575974"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"Supplement_2","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Marie Sk\u0142odowska-Curie Career Development Fellowship","award":["713654"],"award-info":[{"award-number":["713654"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Emerging evidence suggests health-promoting properties of increased protein intake. There is increased interest in plant protein but a dearth of information in relation to its impact on muscle function. The objective of the present work was to examine the impact of intake of different types of proteins on muscle functional parameters including handgrip strength, biomarkers of metabolic health, sleep quality and quality of life in a group of older adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Healthy men and women aged 50\u00a0years and older entered a double-blinded, randomised, controlled nutritional intervention study with three parallel arms: high plant protein, high dairy protein and low protein. Participants consumed once daily a ready-to-mix shake (containing 20\u00a0g of protein in high protein groups) for 12\u00a0weeks. Changes in handgrip and leg strength, body composition, metabolic health, quality of life and sleep quality were analysed by linear mixed models in an intention-to-treat approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eligible participants (n\u00a0=\u2009171) were randomly assigned to the groups (plant: n\u00a0=\u200960, dairy: n\u00a0=\u200956, low protein: n\u00a0=\u200955) and 141 completed the study. Handgrip strength increased after the intervention (Ptime\u00a0=\u20090.038), with no significant difference between the groups. There was no significant difference between groups for any other health outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In a population of older adults, increasing protein intake by 20\u00a0g daily for 12\u00a0weeks (whether plant-based or dairy-based) did not result in significant differences in muscle function, body composition, metabolic health, sleep quality or quality of life, compared with the low protein group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ageing\/afae031","type":"journal-article","created":{"date-parts":[[2024,2,12]],"date-time":"2024-02-12T16:13:18Z","timestamp":1707754398000},"page":"ii13-ii19","source":"Crossref","is-referenced-by-count":8,"title":["Impact of increased protein intake in older adults: a 12-week double-blind randomised controlled trial"],"prefix":"10.1093","volume":"53","author":[{"given":"Janine","family":"Wirth","sequence":"first","affiliation":[{"name":"UCD UCD Institute of Food and Health, UCD School of Agriculture and Food Science, , Belfield, Dublin 4, Ireland"},{"name":"UCD UCD Conway Institute of Biomolecular and Biomedical Research, , Belfield, Dublin 4, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Segat","sequence":"additional","affiliation":[{"name":"Kerry Group, Global Technology and Innovation Center , Applied Health and Nutrition - Nutritional and Functional Proteins, Naas, Co. Kildare, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katy","family":"Horner","sequence":"additional","affiliation":[{"name":"UCD Institute of Sport and Health, , Belfield, Dublin 4, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Crognale","sequence":"additional","affiliation":[{"name":"UCD Institute of Sport and Health, , Belfield, Dublin 4, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Smith","sequence":"additional","affiliation":[{"name":"St. Vincents University Hospital Department of Clinical Chemistry, , Elm Park, Dublin 4, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice","family":"O\u2019Sullivan","sequence":"additional","affiliation":[{"name":"Kerry Group, Global Technology and Innovation Center , Applied Health and Nutrition - Nutritional and Functional Proteins, Naas, Co. Kildare, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine","family":"Brennan","sequence":"additional","affiliation":[{"name":"UCD UCD Institute of Food and Health, UCD School of Agriculture and Food Science, , Belfield, Dublin 4, Ireland"},{"name":"UCD UCD Conway Institute of Biomolecular and Biomedical Research, , Belfield, Dublin 4, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,5,15]]},"reference":[{"key":"2024051505594171700_ref1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1007\/s11892-019-1249-8","article-title":"Benefit-to-risk balance of weight loss interventions in older adults with obesity","volume":"19","author":"DiMilia","year":"2019","journal-title":"Curr Diab Rep"},{"key":"2024051505594171700_ref2","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1093\/nutrit\/nuv065","article-title":"Effects of dietary protein intake on body composition changes 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