{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T06:32:24Z","timestamp":1784874744548,"version":"3.55.0"},"reference-count":46,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T00:00:00Z","timestamp":1710720000000},"content-version":"vor","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Janet Owens Parkinson\u2019s UK Senior Research Fellowship","award":["F-1801"],"award-info":[{"award-number":["F-1801"]}]},{"name":"MRC Discovery Medicine North Doctoral Training Partnership"},{"name":"Newcastle Hospitals Charity","award":["8092"],"award-info":[{"award-number":["8092"]}]},{"name":"Clinical Research Fellowship"},{"DOI":"10.13039\/501100000320","name":"Alzheimer\u2019s Society","doi-asserted-by":"publisher","award":["239"],"award-info":[{"award-number":["239"]}],"id":[{"id":"10.13039\/501100000320","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000320","name":"Alzheimer\u2019s Society","doi-asserted-by":"publisher","award":["AS-CTF-14001"],"award-info":[{"award-number":["AS-CTF-14001"]}],"id":[{"id":"10.13039\/501100000320","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"UK Medical Research Council","doi-asserted-by":"publisher","award":["G0601022"],"award-info":[{"award-number":["G0601022"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000320","name":"Alzheimer\u2019s Society","doi-asserted-by":"publisher","award":["294"],"award-info":[{"award-number":["294"]}],"id":[{"id":"10.13039\/501100000320","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institute for Health and Care Research (NIHR) Newcastle Biomedical Research Centre"},{"DOI":"10.13039\/501100003776","name":"Newcastle upon Tyne Hospitals NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003776","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000774","name":"Newcastle University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000774","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NIHR\/Wellcome Trust Clinical Research Facility"},{"name":"NIHR South West Peninsula Applied Research Collaboration"},{"name":"Exeter Biomedical Research Centre"},{"name":"Health Education England (HEE)\/NIHR"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Inpatient prevalence of Parkinson\u2019s disease (PD) delirium varies widely across the literature. Delirium in general older populations is associated with adverse outcomes, such as increased mortality, dementia, and institutionalisation. However, to date there are no comprehensive prospective studies in PD delirium. This study aimed to determine delirium prevalence in hospitalised PD participants and the association with adverse outcomes, compared to a control group of older adults without PD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Participants were hospitalised inpatients from the \u2018Defining Delirium and its Impact in Parkinson\u2019s Disease\u2019 and the \u2018Delirium and Cognitive Impact in Dementia\u2019 studies comprising 121 PD participants and 199 older adult controls. Delirium was diagnosed prospectively using the Diagnostic and Statistical Manual of Mental Disorders 5th Edition criteria. Outcomes were determined by medical note reviews and\/or home visits 12\u00a0months post hospital discharge.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Delirium was identified in 66.9% of PD participants compared to 38.7% of controls (p\u2009&amp;lt;\u20090.001). In PD participants only, delirium was associated with a significantly higher risk of mortality (HR\u2009=\u20093.3 (95% confidence interval [CI]\u2009=\u20091.3\u20138.6), p\u2009=\u20090.014) and institutionalisation (OR\u2009=\u200910.7 (95% CI = 2.1\u201354.6), p\u2009=\u20090.004) 12\u00a0months post-discharge, compared to older adult controls. However, delirium was associated with an increased risk of developing dementia 12\u00a0months post-discharge in both PD participants (OR\u2009=\u20096.1 (95% CI\u2009=\u20091.3\u201329.5), p\u2009=\u20090.024) and in controls (OR\u2009=\u200913.4 (95% CI\u2009=\u20092.5\u201372.6), p\u2009=\u20090.003).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Delirium is common in hospitalised PD patients, affecting two thirds of patients, and is associated with increased mortality, institutionalisation, and dementia. Further research is essential to understand how to accurately identify, prevent and manage delirium in people with PD who are in hospital.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ageing\/afae046","type":"journal-article","created":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T08:19:51Z","timestamp":1710749991000},"source":"Crossref","is-referenced-by-count":13,"title":["Delirium is more common and associated with worse outcomes in Parkinson\u2019s disease compared to older adult controls: results of two prospective longitudinal cohort studies"],"prefix":"10.1093","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7162-8928","authenticated-orcid":false,"given":"Florence","family":"Gerakios","sequence":"first","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University , Newcastle upon Tyne , UK"},{"name":"Newcastle upon Tyne NHS Foundation Trust , Newcastle upon Tyne , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3126-9163","authenticated-orcid":false,"given":"Alison J","family":"Yarnall","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University , Newcastle upon Tyne , UK"},{"name":"Newcastle upon Tyne NHS Foundation Trust , Newcastle upon Tyne , UK"},{"name":"NIHR Newcastle Biomedical Research Centre , Faculty of Medical Sciences, , UK"},{"name":"Newcastle University , Faculty of Medical Sciences, , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8588-6124","authenticated-orcid":false,"given":"Gemma","family":"Bate","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University , Newcastle upon Tyne , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0558-7811","authenticated-orcid":false,"given":"Laura","family":"Wright","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University , Newcastle upon Tyne , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1560-1955","authenticated-orcid":false,"given":"Daniel","family":"Davis","sequence":"additional","affiliation":[{"name":"MRC Unit for Lifelong Health and Ageing, University College London , London , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1235-360X","authenticated-orcid":false,"given":"Blossom C M","family":"Stephan","sequence":"additional","affiliation":[{"name":"Institute of Mental Health , School of Medicine, , Nottingham , UK"},{"name":"Nottingham University , School of Medicine, , Nottingham , UK"},{"name":"Dementia Centre of Excellence , EnAble Institute, , Perth , Australia"},{"name":"Curtin University , EnAble Institute, , Perth , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0209-2503","authenticated-orcid":false,"given":"Louise","family":"Robinson","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute , Faculty of Medical Sciences, , Newcastle upon Tyne , UK"},{"name":"Newcastle University , Faculty of Medical Sciences, , Newcastle upon Tyne , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5307-663X","authenticated-orcid":false,"given":"Carol","family":"Brayne","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Cambridge , Cambridge , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7905-9336","authenticated-orcid":false,"given":"Glenn","family":"Stebbins","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Rush University Medical Center , Chicago , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7958-6558","authenticated-orcid":false,"given":"John-Paul","family":"Taylor","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University , Newcastle upon Tyne , UK"},{"name":"NIHR Newcastle Biomedical Research Centre , Faculty of Medical Sciences, , UK"},{"name":"Newcastle University , Faculty of Medical Sciences, , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7658-1209","authenticated-orcid":false,"given":"David J","family":"Burn","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University , Newcastle upon Tyne , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8912-4901","authenticated-orcid":false,"given":"Louise M","family":"Allan","sequence":"additional","affiliation":[{"name":"Centre for Research in Ageing and Cognitive Health, University of Exeter , Exeter , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah J","family":"Richardson","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University , Newcastle upon Tyne , UK"},{"name":"NIHR Newcastle Biomedical Research Centre , Faculty of Medical Sciences, , UK"},{"name":"Newcastle University , Faculty of Medical Sciences, , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2608-8285","authenticated-orcid":false,"given":"Rachael A","family":"Lawson","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University , Newcastle upon Tyne , UK"},{"name":"NIHR Newcastle Biomedical Research Centre , Faculty of Medical Sciences, , UK"},{"name":"Newcastle University , Faculty of Medical Sciences, , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,3,15]]},"reference":[{"key":"2024031808090293300_ref1","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/s41572-020-00223-4","article-title":"Delirium","volume":"6","author":"Wilson","year":"2020","journal-title":"Nat Rev Dis Primers"},{"key":"2024031808090293300_ref2","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1001\/jama.2017.12067","article-title":"Delirium in older persons: advances in diagnosis and treatment","volume":"318","author":"Oh","year":"2017","journal-title":"JAMA"},{"key":"2024031808090293300_ref3","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1007\/s00415-015-7760-1","article-title":"Review of delirium in patients with Parkinson's disease","volume":"262","author":"Vardy","year":"2015","journal-title":"J Neurol"},{"key":"2024031808090293300_ref4","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1186\/s12916-019-1458-7","article-title":"Delirium is prevalent in older hospital inpatients and associated with adverse outcomes: results of a prospective multi-Centre study on world delirium awareness day","volume":"17","author":"Geriatric Medicine Research C","year":"2019","journal-title":"BMC Med"},{"key":"2024031808090293300_ref5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.parkreldis.2018.09.025","article-title":"Defining delirium in idiopathic Parkinson's disease: a systematic review","volume":"64","author":"Lawson","year":"2019","journal-title":"Parkinsonism Relat Disord"},{"key":"2024031808090293300_ref6","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s00702-019-01980-7","article-title":"Management of delirium in Parkinson's disease","volume":"126","author":"Ebersbach","year":"2019","journal-title":"J Neural Transm (Vienna)"},{"key":"2024031808090293300_ref7","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/acps.13470","article-title":"Documentation and diagnosis of delirium in Parkinson's disease","volume":"147","author":"Cullinan","year":"2022","journal-title":"Acta Psychiatr Scand"},{"key":"2024031808090293300_ref8","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1093\/ageing\/afaa244","article-title":"Recurrent delirium over 12 months predicts dementia: results of the delirium and cognitive impact in dementia (DECIDE) study","volume":"50","author":"Richardson","year":"2021","journal-title":"Age Ageing"},{"key":"2024031808090293300_ref9","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1186\/s12877-021-02419-z","article-title":"Correction to: association between components of the delirium syndrome and outcomes in hospitalised adults: a systematic review and meta-analysis","volume":"21","author":"Tieges","year":"2021","journal-title":"BMC Geriatr"},{"key":"2024031808090293300_ref10","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/psyg.12914","article-title":"Poor prognostic impact of delirium: especially on mortality and institutionalisation","volume":"23","author":"Tachibana","year":"2023","journal-title":"Psychogeriatrics"},{"key":"2024031808090293300_ref11","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/s41531-021-00234-2","article-title":"First delirium episode in Parkinson's disease and parkinsonism: incidence, predictors, and outcomes","volume":"7","author":"Green","year":"2021","journal-title":"NPJ Parkinsons Dis"},{"key":"2024031808090293300_ref12","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/s12877-017-0479-3","article-title":"Protocol for the delirium and cognitive impact in dementia (DECIDE) study: a nested prospective longitudinal cohort study","volume":"17","author":"Richardson","year":"2017","journal-title":"BMC Geriatr"},{"key":"2024031808090293300_ref13","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","article-title":"Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases","volume":"55","author":"Hughes","year":"1992","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2024031808090293300_ref14","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/1471-2318-14-87","article-title":"The descriptive epidemiology of delirium symptoms in a large population-based cohort study: results from the Medical Research Council cognitive function and ageing study (MRC CFAS)","volume":"14","author":"Davis","year":"2014","journal-title":"BMC Geriatr"},{"key":"2024031808090293300_ref15","volume-title":"BRITAIN Mental Capacity Act 2005","author":"GREAT","year":"2005"},{"key":"2024031808090293300_ref16","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1111\/j.1532-5415.2011.03597.x","article-title":"The identification of frailty: a systematic literature review","volume":"59","author":"Sternberg","year":"2011","journal-title":"J Am Geriatr Soc"},{"key":"2024031808090293300_ref17","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1016\/S0140-6736(13)61570-6","article-title":"A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the cognitive function and ageing study I and II","volume":"382","author":"Matthews","year":"2013","journal-title":"Lancet"},{"key":"2024031808090293300_ref18","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/mdc3.12921","article-title":"Levodopa equivalent dose conversion factors: an updated proposal including Opicapone and safinamide","volume":"7","author":"Schade","year":"2020","journal-title":"Mov Disord Clin Pract"},{"key":"2024031808090293300_ref19","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/j.jagp.2013.05.003","article-title":"Abnormal level of arousal as a predictor of delirium and inattention: an exploratory study","volume":"21","author":"Tieges","year":"2013","journal-title":"Am J Geriatr Psychiatry"},{"key":"2024031808090293300_ref20","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1002\/jhm.1003","article-title":"Serial administration of a modified Richmond agitation and sedation scale for delirium screening","volume":"7","author":"Chester","year":"2012","journal-title":"J Hosp Med"},{"key":"2024031808090293300_ref21","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM-5","author":"American Psychiatric Association D","year":"2013"},{"key":"2024031808090293300_ref22","doi-asserted-by":"crossref","first-page":"e111823","DOI":"10.1371\/journal.pone.0111823","article-title":"Validation of a consensus method for identifying delirium from hospital records","volume":"9","author":"Kuhn","year":"2014","journal-title":"PloS One"},{"key":"2024031808090293300_ref23","first-page":"S81","article-title":"Parkinson's disease dementia: definitions, guidelines, and research perspectives in diagnosis","volume":"64 Suppl 2","author":"Goetz","year":"2008","journal-title":"Ann Neurol"},{"key":"2024031808090293300_ref24","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.3233\/JPD-212581","article-title":"Which neuropsychological tests? Predicting cognitive decline and dementia in Parkinson's disease in the ICICLE-PD cohort","volume":"11","author":"Lawson","year":"2021","journal-title":"J Parkinsons Dis"},{"key":"2024031808090293300_ref25","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1017\/S1041610204000390","article-title":"The informant questionnaire on cognitive decline in the elderly (IQCODE): a review","volume":"16","author":"Jorm","year":"2004","journal-title":"Int Psychogeriatr"},{"key":"2024031808090293300_ref26","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","article-title":"The Montreal cognitive assessment, MoCA: a brief screening tool for mild cognitive impairment","volume":"53","author":"Nasreddine","year":"2005","journal-title":"J Am Geriatr Soc"},{"key":"2024031808090293300_ref27","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1002\/mds.21507","article-title":"Clinical diagnostic criteria for dementia associated with Parkinson's disease","volume":"22","author":"Emre","year":"2007","journal-title":"Mov Disord"},{"key":"2024031808090293300_ref28","volume-title":"A Package for Survival Analysis in R","author":"Therneau","year":"2023"},{"key":"2024031808090293300_ref29","volume-title":"Survminer: Drawing Survival Curves Using 'ggplot2'","author":"Alboukadel Kassambara MKaPB","year":"2021"},{"key":"2024031808090293300_ref30","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-319-24277-4","volume-title":"ggplot2: Elegant Graphics for Data Analysis","author":"Wickham","year":"2016"},{"key":"2024031808090293300_ref31","volume-title":"Ggpubr: 'ggplot2' Based Publication Ready Plots","author":"Alboukadel Kassambara MKaPB","year":"2022"},{"key":"2024031808090293300_ref32","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1093\/ageing\/afq052","article-title":"Hospital use, institutionalisation and mortality associated with delirium","volume":"39","author":"Eeles","year":"2010","journal-title":"Age Ageing"},{"key":"2024031808090293300_ref33","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1001\/archinte.162.4.457","article-title":"Delirium predicts 12-month mortality","volume":"162","author":"McCusker","year":"2002","journal-title":"Arch Intern Med"},{"key":"2024031808090293300_ref34","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.h2538","article-title":"Outcome of delirium in critically ill patients: systematic review and meta-analysis","volume":"350","author":"Salluh","year":"2015","journal-title":"BMJ"},{"key":"2024031808090293300_ref35","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1001\/jama.2010.1013","article-title":"Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis","volume":"304","author":"Witlox","year":"2010","journal-title":"JAMA"},{"key":"2024031808090293300_ref36","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.parkreldis.2005.05.002","article-title":"Delirium in Parkinson's disease patients. A five-year follow-up study","volume":"11","author":"Serrano-Duenas","year":"2005","journal-title":"Parkinsonism Relat Disord"},{"key":"2024031808090293300_ref37","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1111\/j.1532-5415.2000.tb06891.x","article-title":"Predictors of nursing home placement in Parkinson's disease: a population-based, prospective study","volume":"48","author":"Aarsland","year":"2000","journal-title":"J Am Geriatr Soc"},{"key":"2024031808090293300_ref38","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1007\/s40263-018-0540-6","article-title":"Assessment and Management of Neuropsychiatric Symptoms in Parkinson's disease","volume":"32","author":"Mueller","year":"2018","journal-title":"CNS Drugs"},{"key":"2024031808090293300_ref39","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1002\/mds.26563","article-title":"Serum immune markers and disease progression in an incident Parkinson's disease cohort (ICICLE-PD)","volume":"31","author":"Williams-Gray","year":"2016","journal-title":"Mov Disord"},{"key":"2024031808090293300_ref40","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.49950","article-title":"Predisposing and precipitating factors associated with delirium: a systematic review","volume":"6","author":"Ormseth","year":"2023","journal-title":"JAMA Netw Open"},{"key":"2024031808090293300_ref41","article-title":"Frailty in Parkinson's disease: a systematic review and meta-analysis","volume":"4","author":"McMillan","year":"2021","journal-title":"Clin Park Relat Disord"},{"key":"2024031808090293300_ref42","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1111\/jgs.15503","article-title":"Frailty and delirium in older adults: a systematic review and meta-analysis of the literature","volume":"66","author":"Persico","year":"2018","journal-title":"J Am Geriatr Soc"},{"key":"2024031808090293300_ref43","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.jamda.2021.01.065","article-title":"The association between frailty and delirium among hospitalized patients: an updated meta-analysis","volume":"22","author":"Zhang","year":"2021","journal-title":"J Am Med Dir Assoc"},{"key":"2024031808090293300_ref44","doi-asserted-by":"crossref","first-page":"S262","DOI":"10.1111\/j.1532-5415.2011.03674.x","article-title":"Vulnerability: the crossroads of frailty and delirium","volume":"59","author":"Quinlan","year":"2011","journal-title":"J Am Geriatr Soc"},{"key":"2024031808090293300_ref45","first-page":"CD005563","article-title":"Interventions for preventing delirium in hospitalised non-ICU patients","volume":"2016","author":"Siddiqi","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"2024031808090293300_ref46","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/gps.5270","article-title":"Identifying delirium in Parkinson disease: a pilot study","volume":"35","author":"Lawson","year":"2020","journal-title":"Int J Geriatr Psychiatry"}],"container-title":["Age and Ageing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ageing\/article-pdf\/53\/3\/afae046\/56985069\/afae046.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ageing\/article-pdf\/53\/3\/afae046\/56985069\/afae046.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T08:20:33Z","timestamp":1710750033000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ageing\/article\/doi\/10.1093\/ageing\/afae046\/7629821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,1]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ageing\/afae046","relation":{},"ISSN":["0002-0729","1468-2834"],"issn-type":[{"value":"0002-0729","type":"print"},{"value":"1468-2834","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,3,1]]},"published":{"date-parts":[[2024,3,1]]},"article-number":"afae046"}}