{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T13:13:44Z","timestamp":1784639624421,"version":"3.55.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T00:00:00Z","timestamp":1726876800000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>An observational cohort study conducted at a tertiary referral center for aortic surgery to describe the medical and surgical characteristics of patients assessed for abdominal aortic aneurysm repair and examine associations with 12-month outcome.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients with aortic aneurysms referred for discussion at the aortic multidisciplinary meeting (MDM). Data were collected via a prospectively maintained clinical database and included aneurysm characteristics, patient demographics, co-morbidities, geriatric syndromes, including frailty, management decision and 12-month mortality, both aneurysm-related and all-cause including cause of death. The operative and non-operative groups were compared statistically.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>621 patients referred to aortic MDM; 292 patients listed for operative management, 141 patients continued on surveillance, 138 patients for non-operative management. There was a higher 12-month mortality rate in the non-operative group compared to the operative group (41% vs 7%, P =\u2009&amp;lt;0.001). In the non-operative group, 16 patients (29%) died of aneurysm rupture within 12\u00a0months, with 39 patients (71%) dying from other medical causes. Non-operatively managed patients were older, more likely to have cardiac and respiratory disease and more likely to be living with frailty, cognitive impairment and functional limitation, compared to the operative group.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This study shows that preoperative geriatric syndromes and increased comorbidity lead to shared decision to non-operatively manage asymptomatic aortic aneurysms. Twelve-month mortality is higher in the non-operative group with the majority of deaths occurring due to cause other than aneurysm rupture. These findings support the need for preoperative comprehensive geriatric assessment followed by multispecialty discussion and shared decision making.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ageing\/afae193","type":"journal-article","created":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T14:06:37Z","timestamp":1726927597000},"source":"Crossref","is-referenced-by-count":8,"title":["Preoperative clinical characteristics and 12-month outcomes following operative or non-operative management of asymptomatic aortic aneurysms"],"prefix":"10.1093","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9258-2532","authenticated-orcid":false,"given":"Phoebe","family":"Scarfield","sequence":"first","affiliation":[{"name":"Perioperative Medicine for Older People Undergoing Surgery (POPS) , Department of Ageing and Health, , London SE1 9RT, UK"},{"name":"Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , Department of Ageing and Health, , London SE1 9RT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy R","family":"Sharkey","sequence":"additional","affiliation":[{"name":"Department of Cancer Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London , London SE1 9RT, UK"},{"name":"Department of Radiology, Guy's and St Thomas' NHS Foundation Trust , London SE1 9RT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jugdeep K","family":"Dhesi","sequence":"additional","affiliation":[{"name":"Honorary Professor , School of Life Course and Population Sciences, Faculty of Life Sciences and Medicine, , WC2R 2LS, UK"},{"name":"King\u2019s College London , School of Life Course and Population Sciences, Faculty of Life Sciences and Medicine, , WC2R 2LS, UK"},{"name":"Consultant Geriatrician , Perioperative Medicine for Older People Undergoing Surgery (POPS), Department of Ageing and Health, , London SE1 9RT, UK"},{"name":"Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , Perioperative Medicine for Older People Undergoing Surgery (POPS), Department of Ageing and Health, , London SE1 9RT, UK"},{"name":"Honorary Associate Professor Division of Surgery and Interventional Science, University College London , WC1E 6BT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bijan","family":"Modarai","sequence":"additional","affiliation":[{"name":"Consultant Vascular Surgeon, Guy\u2019s & St. Thomas\u2019 NHS Trust , SE1 7EH"},{"name":"Professor of Vascular Surgery at King\u2019s College London and Guy\u2019s and St Thomas\u2019 NHS Trust , SE1 7EH"},{"name":"School of Cardiovascular and Metabolic Medicine and Sciences, BHF Centre of Excellence , London WC2R 2LS, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R","family":"Tyrrell","sequence":"additional","affiliation":[{"name":"Consultant Vascular Surgeon, Guy\u2019s & St. Thomas\u2019 NHS Trust , SE1 7EH"},{"name":"Cleveland Clinic London , SW1X 7HY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith S L","family":"Partridge","sequence":"additional","affiliation":[{"name":"Consultant Geriatrician , Perioperative Medicine for Older People Undergoing Surgery (POPS), Department of Ageing and Health, , London SE1 9RT, UK"},{"name":"Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , Perioperative Medicine for Older People Undergoing Surgery (POPS), Department of Ageing and Health, , London SE1 9RT, UK"},{"name":"Honorary Senior Lecturer , School of Life Course and Population Sciences, Faculty of Life Sciences and Medicine, , WC2R 2LS"},{"name":"King\u2019s College London , School of Life Course and Population Sciences, Faculty of Life Sciences and Medicine, , WC2R 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