{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:12:21Z","timestamp":1787008341607,"version":"build-2736575974"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T00:00:00Z","timestamp":1725580800000},"content-version":"vor","delay-in-days":5,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>People living in care homes often have problems with pain, anxiety and depression. Whether being on analgesia, anxiolytics or antidepressants has any bearing on pain severity and quality of life (QoL) in this population, requires further investigation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>(i) to examine the relationship between pain, anxiety and depression and medication use in care home residents and (ii) to compare those on medications to treat pain, anxiety and depression, and those who were not, and associations with pain severity and overall QoL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a secondary analysis of a randomised controlled trial testing a falls prevention intervention in care homes. We recorded pain, anxiety and depression, QoL measurements and prescribed medication use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In 1589 participants, the mean age was 84.7\u00a0years (\u00b19.3 SD), 32.2% were male and 67.3% had a diagnosis of dementia. 54.3% and 53.2% of participants had some level of pain and anxiety or depression respectively, regardless of prescribed medication use. There was a direct association between pain severity and being on any analgesia, opioid analgesia, and antidepressants, but no associations between pain severity and use of paracetamol and anxiolytics. QoL was best for residents with no pain and not on any analgesia, anxiolytics or antidepressants and worst for those with moderate-extreme pain and taking at least two of these classes of medications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Many care home residents live with pain, anxiety and depression. Addressing residents\u2019 pain may also increase their quality of life, but using medication alone to reach this goal may be inadequate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ageing\/afae196","type":"journal-article","created":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T23:41:04Z","timestamp":1724283664000},"source":"Crossref","is-referenced-by-count":6,"title":["Quality of life, pain and use of analgesic, anxiolytic and antidepressant medication, in people living in care homes"],"prefix":"10.1093","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3865-7334","authenticated-orcid":false,"given":"Jemima T","family":"Collins","sequence":"first","affiliation":[{"name":"Centre for Rehabilitation and Ageing , Injury, Recovery and Inflammation Sciences Academic Unit, School of Medicine, , Nottingham, UK"},{"name":"the University of Nottingham , Injury, Recovery and Inflammation Sciences Academic Unit, School of Medicine, , Nottingham, UK"},{"name":"University Hospitals Derby and Burton NHS Trust , Derby, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Irvine","sequence":"additional","affiliation":[{"name":"Centre for Research in Public Health and Community Care, University of Hertfordshire , Hatfield, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pip","family":"Logan","sequence":"additional","affiliation":[{"name":"Centre for Rehabilitation and Ageing , Injury, Recovery and Inflammation Sciences Academic Unit, School of Medicine, , Nottingham, UK"},{"name":"the University of Nottingham , Injury, Recovery and Inflammation Sciences Academic Unit, School of Medicine, , Nottingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Robinson","sequence":"additional","affiliation":[{"name":"Centre for Rehabilitation and Ageing , Injury, Recovery and Inflammation Sciences Academic Unit, School of Medicine, , Nottingham, UK"},{"name":"the University of Nottingham , Injury, Recovery and Inflammation Sciences Academic Unit, School of Medicine, , Nottingham, UK"},{"name":"Research and Innovation, Nottingham University Hospitals NHS Trust , Nottingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Sims","sequence":"additional","affiliation":[{"name":"Norwich Medical School, University of East Anglia , Norwich, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam L","family":"Gordon","sequence":"additional","affiliation":[{"name":"Centre for Rehabilitation and Ageing , Injury, Recovery and Inflammation Sciences Academic Unit, School of Medicine, , Nottingham, UK"},{"name":"the University of Nottingham , Injury, Recovery and Inflammation Sciences Academic Unit, School of Medicine, , Nottingham, UK"},{"name":"University Hospitals Derby and Burton NHS Trust , Derby, UK"},{"name":"Applied Research Collaboration-East Midlands (ARC-EM) , Nottingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,9,6]]},"reference":[{"key":"2024090603371023700_ref1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s12603-014-0001-y","article-title":"Patterns of chronic co-morbid medical conditions in older residents of U.S. nursing homes: Differences between the sexes and across the agespan","volume":"18","author":"Moore","year":"2014","journal-title":"J Nutr Health Aging"},{"key":"2024090603371023700_ref2","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.jamda.2020.11.025","article-title":"Social connection in long-term care homes: A scoping review of published research on the mental health impacts and potential strategies during COVID-19","volume":"22","author":"Bethell","year":"2021","journal-title":"J Am Med Dir Assoc"},{"key":"2024090603371023700_ref3","volume-title":"Care Home Market Study: Summary of the Final Report","author":"Competition and Markets Authority"},{"key":"2024090603371023700_ref4","doi-asserted-by":"crossref","first-page":"afac306","DOI":"10.1093\/ageing\/afac306","article-title":"Chronic pain in people living with dementia: Challenges to recognising and managing pain, and personalising intervention by phenotype","volume":"52","author":"Collins","year":"2023","journal-title":"Age Ageing"},{"key":"2024090603371023700_ref5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s40266-024-01101-4","article-title":"The difficulties of managing pain in people living with frailty: The potential for digital phenotyping","volume":"41","author":"Collins","year":"2024","journal-title":"Drugs Aging"},{"key":"2024090603371023700_ref6","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/s12877-016-0328-9","article-title":"Exploring the prevalence and variance of cognitive impairment, pain, neuropsychiatric symptoms and ADL dependency among persons living in nursing homes; 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