{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:22:09Z","timestamp":1791595329855,"version":"4.3.4"},"reference-count":61,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:00:00Z","timestamp":1728259200000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"European Union's Horizon 2020 Research and Innovation Programme","award":["769574"],"award-info":[{"award-number":["769574"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Falls have high socioeconomic costs. Information and communication technologies may support provision and monitoring of multisensory (MSR) physiotherapy programmes. The HOLOBalance platform used augmented reality holograms to provide patient-centred, individualised MSR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the platform\u2019s safety, acceptability and feasibility, investigate functional gait and dynamic balance benefits and provide data for a definitive trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and setting<\/jats:title><jats:p>Single-blinded pilot randomised controlled feasibility study. Interventions were conducted at clinical sites or participants\u2019 homes in three European countries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Community-dwelling older adults (median age 73\u00a0years; 64.2% female) at risk of falls were enrolled (May 2020-August 2021).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants were randomised to an 8-week clinic or home-based telerehabilitation MSR or OTAGO (control group) programme. Compliance, satisfaction, and adverse events determined feasibility. Clinical outcomes, assessed (blinded) within one-week prior to and post-intervention, included functional gait assessment (FGA), Mini BESTest and cognitive function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Randomisation to completion rate was 76.15% with 109 participants recruited (n\u2009=\u2009289 screened). Drop-out rate was similar between groups. Adverse events were reported (n\u2009=\u20093) in the control group. Sixty-nine percent would recommend the HOLOBalance intervention. Findings were similar for the home and clinic-based arms of each intervention; data was combined for analysis. FGA (95%CI [1.63, 4.19]) and Mini-BESTest (95%CI [1.46, 3.93]) showed greater improvement in the HOLOBalance group with a clinically meaningful change of 4\/30 noted for the FGA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>HOLObalance was feasible to implement and acceptable to older adults at risk of falls, with FGA and Mini-BEST improvements exceeding those for the OTAGO programme. A definitive trial is warranted.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ageing\/afae214","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T13:02:50Z","timestamp":1728306170000},"source":"Crossref","is-referenced-by-count":14,"title":["Feasibility and acceptability of the HOLObalance telerehabilitation system compared with standard care for older adults at risk of falls: the HOLOBalance assessor blinded pilot randomised controlled study"],"prefix":"10.1093","volume":"53","author":[{"given":"Marousa","family":"Pavlou","sequence":"first","affiliation":[{"name":"Centre for Human and Applied Physiological Sciences, King\u2019s College London , London,","place":["UK"]},{"name":"Ear Institute, University College London , London,","place":["UK"]},{"name":"Department of Audiovestibular Medicine , Royal National ENT and Eastman Dental Hospitals, , London,","place":["UK"]},{"name":"University College London Hospitals NHS Foundation Trust , Royal National ENT 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Athens,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitris","family":"Kikidis","sequence":"additional","affiliation":[{"name":"1st Department of Otorhinolaryngology , Head and Neck Surgery, , Athens,","place":["Greece"]},{"name":"National and Kapodistrian University of Athens, Hippocrateion General Hospital , Head and Neck Surgery, , Athens,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanasios","family":"Bibas","sequence":"additional","affiliation":[{"name":"1st Department of Otorhinolaryngology , Head and Neck Surgery, , Athens,","place":["Greece"]},{"name":"National and Kapodistrian University of Athens, Hippocrateion General Hospital , Head and Neck Surgery, , Athens,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitris","family":"Gatsios","sequence":"additional","affiliation":[{"name":"Unit of Medical Technology and Intelligent Information Systems , Department of Materials Science and Engineering, , Ioannina,","place":["Greece"]},{"name":"University of Ioannina , Department of Materials Science and Engineering, , Ioannina,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vassilis","family":"Tsakanikas","sequence":"additional","affiliation":[{"name":"Unit of Medical Technology and Intelligent Information Systems , Department of Materials Science and Engineering, , Ioannina,","place":["Greece"]},{"name":"University of Ioannina , Department of Materials Science and Engineering, , Ioannina,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios I","family":"Fotiadis","sequence":"additional","affiliation":[{"name":"Unit of Medical Technology and Intelligent Information Systems , Department of Materials Science and Engineering, , Ioannina,","place":["Greece"]},{"name":"University of Ioannina , Department of Materials Science and Engineering, , Ioannina,","place":["Greece"]},{"name":"Biomedical Research Institute , Ioannina,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Koutsouris","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Laboratory , School of Electrical and Computer Engineering, , Athens,","place":["Greece"]},{"name":"National Technical University of Athens , School of Electrical and Computer Engineering, , Athens,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Steinicke","sequence":"additional","affiliation":[{"name":"Human-Computer Interaction Group , Department of Informatics, , Hamburg,","place":["Germany"]},{"name":"Universit\u00e4t Hamburg , Department of Informatics, , Hamburg,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle Daniela","family":"Walz","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neuroscience , Faculty of Medicine, Medical Center, , Freiburg,","place":["Germany"]},{"name":"University of Freiburg , Faculty of Medicine, Medical Center, , Freiburg,","place":["Germany"]},{"name":"Department of Sport and Sport Science, University of Freiburg , Freiburg,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Maurer","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neuroscience , Faculty of Medicine, Medical Center, , Freiburg,","place":["Germany"]},{"name":"University of Freiburg , Faculty of Medicine, Medical Center, , Freiburg,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Papadopoulou","sequence":"additional","affiliation":[{"name":"1st Department of Otorhinolaryngology , Head and Neck Surgery, , Athens,","place":["Greece"]},{"name":"National and Kapodistrian University of Athens, Hippocrateion General Hospital , Head and Neck 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