{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:57:53Z","timestamp":1791086273231,"version":"4.1.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Mobilisation within the first day following hip fracture surgery is recommended. However, an in-depth analysis of the association between early mobilisation and the risk of infection is lacking.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To examine the association between early mobilisation and the subsequent risk of hospital-treated infections following hip fracture surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Using nationwide registries, we included 36\u00a0229 patients aged \u226565 who underwent surgery for hip fracture (2016\u201321). Exposure was time from surgery to first mobilisation in hours. Outcomes were any hospital-treated infection, pneumonia, urinary tract infection and sepsis within 2\u201330\u00a0days and reoperation due to surgical-site infection within 2\u2013365\u00a0days of surgery. We calculated cumulative incidences (risks), risk differences (RD) and hazard ratios (HR) with 95% confidence intervals (CIs) using the inverse probability of treatment (IPT) weighted method to account for confounding.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Overall, 27\u00a0174 (75%) patients were mobilised \u226424\u00a0h, 2890 (8%) between 24 and 36\u00a0h, and 6165 (17%) were mobilised &amp;gt;36\u00a0h of surgery or had no registration of mobilisation time.<\/jats:p>\n                  <jats:p>In the weighted analysis, the risk of any infection was 12.9% (CI 11.7%\u201314.2%) in patients mobilised 24\u201336\u00a0h of surgery and 10.9% (CI 10.5%\u201311.7%) in those mobilised \u226424\u00a0h, corresponding to RD of 2.0% (CI 0.7\u20133.3) and HR of 1.2 (CI 1.1\u20131.3). Similar associations were observed for pneumonia and urinary tract infection but not for sepsis and reoperation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Infection is a common complication after hip fracture surgery. Mobilisation within 24\u00a0h is clearly associated with reduced infection risk. Our results emphasise the importance of early mobilisation and suggest a possible pathway for reducing complications and mortality after hip fracture.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ageing\/afaf007","type":"journal-article","created":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T12:14:01Z","timestamp":1736597641000},"source":"Crossref","is-referenced-by-count":22,"title":["Early mobilisation after hip fracture surgery reduces the risk of infection: an inverse probability of treatment weighted analysis"],"prefix":"10.1093","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0112-5801","authenticated-orcid":false,"given":"Thomas Johannesson","family":"Hjelholt","sequence":"first","affiliation":[{"name":"Department of Geriatrics, Aarhus University Hospital , Aarhus ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ina Trolle","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, Aarhus University Hospital , Aarhus ,","place":["Denmark"]},{"name":"Department of Clinical Epidemiology, Aarhus University , Aarhus, Midtjylland ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten Tange","family":"Kristensen","sequence":"additional","affiliation":[{"name":"Department of Physical and Occupational Therapy, Copenhagen University Hospital ,","place":["Denmark"]},{"name":"Department of Clinical Medicine, University of Copenhagen , Kobenhavn, Region Hovedstaden ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alma Becic","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, Aarhus University Hospital , Aarhus ,","place":["Denmark"]},{"name":"Department of Clinical Epidemiology, Aarhus University , Aarhus, Midtjylland 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