{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T05:13:08Z","timestamp":1792818788976,"version":"4.5.0"},"reference-count":75,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Cognitive impairment, dementia and sarcopenia significantly reduce the quality of life in middle-aged and older adults by impairing daily functioning, making cognitive decline a major concern for healthcare professionals.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To estimate the prevalence of sarcopenia and probable sarcopenia in middle-aged and older adults with cognitive impairment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Six databases\u2014Embase, Ovid MEDLINE, PubMed, CINAHL, Scopus and Web of Science was conducted through February 2025. Cohort and cross-sectional studies included, and a random-effects model was used for pooled prevalence analysis. Cognitive impairment is a decline in cognitive functions, including memory, attention and executive function, covering mild cognitive impairment and dementia. Sarcopenia is decreased skeletal muscle mass and function, assessed by muscle strength or physical performance.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 67 studies involving 23\u00a0532 participants revealed a pooled sarcopenia prevalence of 30.1% and a probable sarcopenia prevalence of 40.5%. Additionally, amongst adults aged 65 and older, the prevalence of sarcopenia was 32.7%. The prevalence of sarcopenia varied by setting: 25.3% in community-dwelling populations, 35.5% in hospitals and 41.5% in institutional settings. Moderating factors included age, female, body mass index, comorbidities and risk factors such as depression, diabetes, hypertension, malnutrition, osteoarthritis, alcohol consumption and smoking.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Approximately one-third of middle-aged and older adults with cognitive impairment demonstrate to have sarcopenia. Early detection and tailored interventions by public health professionals are crucial, particularly for individuals with mild cognitive impairment and dementia. Enhanced preventive strategies are essential to improving outcomes and reducing healthcare costs.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ageing\/afaf114","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T04:39:21Z","timestamp":1746679161000},"source":"Crossref","is-referenced-by-count":14,"title":["Prevalence of sarcopenia in middle-aged and older adults with cognitive impairment: a meta-analysis"],"prefix":"10.1093","volume":"54","author":[{"given":"Jia-You","family":"Ye","sequence":"first","affiliation":[{"name":"School of Nursing, College of Nursing, Taipei Medical University , Taipei City ,","place":["Taiwan"]},{"name":"School of Nursing, College of Medicine, Chang Gung University , Taoyuan City ,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Fang","family":"Chang","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Nursing, Taipei Medical University , Taipei City ,","place":["Taiwan"]},{"name":"Department of Medical Education, Taipei Medical University Hospital , Taipei City ,","place":["Taiwan"]},{"name":"Graduate Institute of Medical Sciences, National Defense Medical Center , Taipei City ,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruey","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Nursing, Taipei Medical University , Taipei City ,","place":["Taiwan"]},{"name":"Department of Nursing , Taipei Medical University-Shuang Ho Hospital, New Taipei City,","place":["Taiwan"]},{"name":"Post-Baccalaureate Program in Nursing, College of Nursing, Taipei Medical University , Taipei City ,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidayat","family":"Arifin","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Nursing, Taipei Medical University , Taipei City ,","place":["Taiwan"]},{"name":"Department of Basic Nursing, Faculty of Nursing, Universitas Airlangga , Surabaya, East Java ,","place":["Indonesia"]},{"name":"Research Group in Medical-Surgical Nursing, Faculty of Nursing, Universitas Airlangga , Surabaya, East Java ,","place":["Indonesia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Hui","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Nursing, Taipei Medical University , Taipei City ,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Jo","family":"Chiang","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Nursing, Taipei Medical University , Taipei City ,","place":["Taiwan"]},{"name":"School of Nursing, National Defense Medical Center , Taipei City ,","place":["Taiwan"]},{"name":"Department of Nursing, Tri-Service General Hospital , Taipei City ,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2683-0825","authenticated-orcid":false,"given":"Kondwani J","family":"Banda","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Nursing, Taipei Medical University , Taipei City ,","place":["Taiwan"]},{"name":"Endoscopy Unit, Surgery Department , Kamuzu Central Hospital, Lilongwe ,","place":["Malawi"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4882-3503","authenticated-orcid":false,"given":"Kuei-Ru","family":"Chou","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Nursing, Taipei Medical University , Taipei City ,","place":["Taiwan"]},{"name":"Department of Nursing, Taipei Medical University-Shuang Ho Hospital , New Taipei City ,","place":["Taiwan"]},{"name":"Research Center in Nursing Clinical Practice, Wan Fang Hospital Taipei Medical University , Taipei City ,","place":["Taiwan"]},{"name":"Psychiatric Research Center, Taipei Medical University Hospital , Taipei City ,","place":["Taiwan"]},{"name":"Research Center for Neuroscience, Taipei Medical University , Taipei City ,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,5,8]]},"reference":[{"key":"2025050800391742200_ref75","article-title":"World population prospects 2024 summary of results","volume":"9","author":"UN","year":"2024","journal-title":"United Nations"},{"key":"2025050800391742200_ref1","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1093\/gerona\/59.1.m24","article-title":"The top 10 hot topics in aging","volume":"59","author":"Morley","year":"2004","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2025050800391742200_ref2","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"American Psychiatric Association; Diagnostic and Statistical Manual of Mental Disorders: DSM-5","author":"American Psychiatric Association, D. 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