{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T23:48:24Z","timestamp":1790034504177,"version":"4.0.1"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Anorexia\/appetite loss is common among older adults and may arise from underlying diseases, adverse drug effects or the physiological ageing process. This study aims to estimate the prevalence of anorexia\/appetite loss in older adults with associated factors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>Systematic review and meta-analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A comprehensive literature search of five electronic databases was conducted on 10 November 2024. Studies were eligible if they reported the prevalence of anorexia\/appetite loss in older adults using the Simplified Nutritional Appetite Questionnaire. A random-effects model was applied to calculate the overall prevalence of anorexia\/appetite loss. Predefined subgroup analyses were conducted to estimate the prevalence of anorexia\/appetite loss among older adults with varying characteristics.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Sixty-two studies from 24 countries (n\u2009=\u200980 176 participants) were included. The pooled prevalence of anorexia\/appetite loss was 29% (95% CI: 26%\u201334%). The pooled prevalence of anorexia\/appetite loss varied geographically, ranging from 22% (95% CI: 17%\u201327%) in South America to 55% (95% CI: 51%\u201359%) in Africa. By setting, anorexia\/appetite loss prevalence was 25% (95% CI: 21%\u201330%; n\u2009=\u200956 172) in communities, 38% (95% CI: 28%\u201350%; n\u2009=\u2009471) in nursing homes and 42% (95% CI: 32%\u201352%; n\u2009=\u20092498) in hospitals. Subgroup analyses showed that female sex, lower educational level, eating alone, oral problems and depression were associated with higher rates of anorexia\/appetite loss.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The high prevalence of anorexia\/appetite loss warrants attention. Further studies should explore a broader array of sociodemographic and biopsychosocial factors to enhance understanding of anorexia\/appetite loss and guide targeted interventions.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ageing\/afaf249","type":"journal-article","created":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T11:43:50Z","timestamp":1757763830000},"source":"Crossref","is-referenced-by-count":2,"title":["Global prevalence of anorexia and appetite loss among older adults: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"54","author":[{"given":"Wenjie","family":"Li","sequence":"first","affiliation":[{"name":"Department of General Medicine, The First Affiliated Hospital of Army Medical University , No. 29 Gaotanyan Street, Shapingba District, Chongqing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Ni","sequence":"additional","affiliation":[{"name":"Department of Infirmary, Wuxi Institute of Technology , Wuxi, Jiangsu ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongxiu","family":"Chen","sequence":"additional","affiliation":[{"name":"Innovation Center of Nursing Research and Nursing Key Laboratory of Sichuan Province, West China Hospital of Sichuan University , Chengdu, Sichuan ,","place":["China"]},{"name":"West China School of Nursing, Sichuan University , Chengdu, Sichuan ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meihong","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Nursing, Southwest Medical University , Luzhou, Sichuan ,","place":["China"]},{"name":"School of Health, The Affiliated Hospital of Southwest Medical University , Luzhou, Sichuan ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanlin","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of General Medicine, The First Affiliated 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