{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:20:12Z","timestamp":1787494812934,"version":"build-2736575974"},"reference-count":55,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T00:00:00Z","timestamp":1775952000000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anxiety and depressive mood are common among older adults at the peri-hospital period, impacting independence and well-being. Hospital factors such as physical symptoms burden (PSB) and sleep quality (SQ), may impact mood trajectories. This study aims to explore changes in anxiety and depressive mood from admission to discharge and one-month post-discharge, assessing the role of SQ, PSB and sedative-hypnotic medications (SHM) burden across timepoints.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a prospective study of older patients (65+) hospitalized in acute medical units. Interviews were conducted at admission, discharge and one-month post-discharge. A two-stage modelling approach was applied, separating in-hospital and peri-hospital trajectories of anxiety and depressive mood. Mixed-models analyses examined contributions of SQ and PSB, controlling for SHM burden, demographic and baseline characteristics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 683 (male: 54.9%; age 77.31\u2009\u00b1\u20096.67), 643 completed discharge interviews and 545 completed one-month post-discharge interviews. Anxiety and depressive mood worsened over time. Poor SQ, greater PSB (Banx\u00a0=\u2009.39, P &amp;lt; .001; Bdep\u00a0=\u00a0.25, P = &amp;lt; .001), and higher SHM burden (Banx = .55, P &amp;lt; .01) significantly predicted worse mental outcomes throughout hospitalization and post-discharge. SQ effects varied by timepoints: poor SQ was associated with heightened anxiety post-discharge (F(2,878) = 7.52, P &amp;lt; .001) and worsened depressive mood during hospitalization (F(2,874) = 7.99, P &amp;lt; .001). Higher SHM burden correlated with depressive mood at discharge (F(2,874) = 4.80, P &amp;lt; .01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Findings highlight the need to address anxiety and depressive mood in hospitalized older adults through improved sleep, symptoms relief, and cautious SHM use. Further research should explore long-term interventions to support mental health during and after hospitalization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ageing\/afag076","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T12:27:28Z","timestamp":1773664048000},"source":"Crossref","is-referenced-by-count":1,"title":["Mental health in the peri-hospital period of older patients: the roles of physical symptoms burden and sleep quality"],"prefix":"10.1093","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2855-0210","authenticated-orcid":false,"given":"Juliana","family":"Smichenko","sequence":"first","affiliation":[{"name":"University of Haifa - Faculty of Social Welfare and Health Sciences, The Cheryl Spencer Department of Nursing , Haifa, Haifa District, 3498838 ,","place":["Israel"]},{"name":"Clalit Research Institute, Innovation Division, Clalit Health Services , Tel-Aviv, Tel-Aviv District, 6209804 ,","place":["Israel"]},{"name":"University of Haifa - The Center of Research and Study of Aging , Haifa, Haifa District, 3498838 ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8234-5218","authenticated-orcid":false,"given":"Anna","family":"Zisberg","sequence":"additional","affiliation":[{"name":"University of Haifa - Faculty of Social Welfare and Health Sciences, The Cheryl Spencer Department of Nursing , Haifa, Haifa District, 3498838 ,","place":["Israel"]},{"name":"University of Haifa - The Center of Research and Study of Aging , Haifa, Haifa District, 3498838 ,","place":["Israel"]},{"name":"University of Haifa - ADVANCE Azrieli Advanced Nursing Center , Haifa, Haifa District, 3498838 ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4371-3567","authenticated-orcid":false,"given":"Tamar","family":"Shochat","sequence":"additional","affiliation":[{"name":"University of Haifa - Faculty of Social Welfare and Health Sciences, The Cheryl Spencer Department of Nursing , Haifa, Haifa District, 3498838 ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,12]]},"reference":[{"key":"2026041304193429000_ref1","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.jpsychores.2019.03.011","article-title":"Trajectories of cognitive-affective depressive symptoms in acutely hospitalized older adults: the hospital-ADL study","volume":"120","author":"Reichardt","year":"2018","journal-title":"J Psychosom Res"},{"key":"2026041304193429000_ref2","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1046\/j.1365-2648.2003.02802.x","article-title":"Anxiety and well-being in older people after discharge from hospital","volume":"44","author":"Kvaal","year":"2003","journal-title":"J Adv Nurs"},{"key":"2026041304193429000_ref3","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1186\/s12877-022-03324-9","article-title":"Comprehensive geriatric assessment is associated with increased antidepressant treatment in frail older people with unplanned hospital admissions\u2014results from the randomised controlled study CGA-Swed","volume":"22","author":"Westg\u00e5rd","year":"2022","journal-title":"BMC Geriatr"},{"key":"2026041304193429000_ref4","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.archger.2011.04.001","article-title":"Patterns and correlates of depression in hospitalized older adults","volume":"54","author":"Ciro","year":"2012","journal-title":"Arch Gerontol Geriatr"},{"key":"2026041304193429000_ref5","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1017\/S1041610209009399","article-title":"Depression and anxiety in medically unwell older adults: prevalence and short-term course","volume":"21","author":"Bryant","year":"2009","journal-title":"Int Psychogeriatrics"},{"key":"2026041304193429000_ref6","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1017\/S1041610215002306","article-title":"Anxiety symptoms during hospitalization of elderly are associated with increased risk of post-discharge falls","volume":"28","author":"Agmon","year":"2016","journal-title":"Int Psychogeriatrics"},{"key":"2026041304193429000_ref7","doi-asserted-by":"publisher","first-page":"3816","DOI":"10.1080\/09638288.2019.1610804","article-title":"Longitudinal depressive and anxiety symptoms of adult injury patients in Kenya and their risk factors","volume":"42","author":"Hung","year":"2019","journal-title":"Disabil Rehabil"},{"key":"2026041304193429000_ref8","doi-asserted-by":"publisher","first-page":"e02235","DOI":"10.1016\/j.heliyon.2019.e02235","article-title":"The effect of anxiety on cognition in older adult inpatients with depression: results from a multicenter observational study","volume":"5","author":"Martinussen","year":"2019","journal-title":"Heliyon."},{"key":"2026041304193429000_ref9","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1002\/gps.5285","article-title":"A prospective investigation of factors associated with depressive symptoms in older adults\u2019 post-hospitalisation","volume":"35","author":"Brown","year":"2020","journal-title":"Int J Geriatr Psychiatry"},{"key":"2026041304193429000_ref10","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1002\/ejp.998","article-title":"Do depression and anxiety profiles over time predict persistent post-surgical pain? 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