{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T12:27:04Z","timestamp":1784204824597,"version":"3.55.0"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"vor","delay-in-days":5,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Only 6% of UK memory services meet Alzheimer\u2019s disease (AD) biomarker access guidelines, limiting psychiatrists\u2019 experience. Emerging AD blood biomarker (BBM) tests will potentially expand access. Exploring implementation barriers and enablers a priori can inform rollout strategies. This study examined current clinical practises, barriers and enablers to implementation and potential interventions to support implementation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In November 2024, Royal College of Psychiatrists Old Age Psychiatry Faculty members (n\u2009=\u2009172) participated in an online survey and four focus groups (n\u2009=\u200916 participants), informed by the Theoretical Domains Framework (TDF) and Behaviour Change Wheel. Demographic data were summarised descriptively. Mean (SD) belief statement scores for TDF domains and percentage agreement were calculated. Multiple linear regression examined associations between TDF domains and intention to use BBMs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Respondents were mainly consultants in England; &amp;lt;33% had used biomarkers. Key barriers to use were: \u2018Knowledge,\u2019 \u2018Environmental Context and Resources\u2019 and \u2018Goals.\u2019 Enablers included: \u2018Behavioural Regulation,\u2019 \u2018Social Influences\u2019 and \u2018Intention.\u2019 Mixed enablers\/barriers included: \u2018Beliefs about Consequences\u2019, \u2018Optimism\u2019 and \u2018Social\/Professional Role &amp; Identity\u2019. In regression analyses, \u2018Memory, Attention and Decision Processes\u2019 (B\u2009=\u20090.44, 95%CI 0.20\u20130.68), \u2018Beliefs about Consequences\u2019(B\u2009=\u20090.45, 95%CI 0.11\u20130.78), and \u2018Social Influences\u2019 (B\u2009=\u20090.24, 95%CI 0.04\u20130.44) were positively associated with intention, while \u2018Optimism\u2019 (B\u2009=\u2009-0.31,95% CI-0.58 to-0.04) and \u2018Emotion\u2019 (B\u2009=\u2009-0.33, 95%CI -0.60 to-0.06) were negatively associated. Key interventions were \u2018Guidelines\u2019 (e.g. appropriate use criteria) and \u2018Environmental Restructuring\u2019 to expand resources and re-organise pathways.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>A complex interplay of barriers and enablers influences AD BBM implementation. Interventions targeting clinician, service and policy levels are required to support their introduction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ageing\/afag117","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T12:48:33Z","timestamp":1776430113000},"source":"Crossref","is-referenced-by-count":1,"title":["Factors influencing implementation of an Alzheimer\u2019s disease blood test among UK old age psychiatrists: mixed-methods study using the theoretical domains framework"],"prefix":"10.1093","volume":"55","author":[{"given":"Jemma","family":"Hazan","sequence":"first","affiliation":[{"name":"Division of Psychiatry, University College London , London ,","place":["UK"]},{"name":"North London NHS Foundation Trust , London ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell","family":"Mealing","sequence":"additional","affiliation":[{"name":"North London NHS Foundation Trust , London 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