{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:40:33Z","timestamp":1792456833462,"version":"4.5.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"vor","delay-in-days":78,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Enabling Research in Care Homes"},{"name":"Chief Scientist of Scotland leads for Ageing, Neuroprogressive and Dementia"},{"name":"Scottish Funding Council Brain Health Alliance for Research Challenges"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dementia is a global challenge, but benefits from local, context-specific evidence. With finite resource, and numerous potential research directions, formal priority setting can help develop equitable and relevant research agendas. We used this approach to establish dementia and brain health research priority questions for Scotland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A steering board of professionals and experts through lived experience guided the process, following established research prioritisation frameworks. Research questions were collected through surveys and refined to create an interim list. This was further rationalised through Delphi-style ranking involving cross-disciplinary, cross-sectoral interest-holders. After reaching consensus, each research question was assessed for potential impact.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Between April and July 2025, 706 participants submitted 2677 questions. These were consolidated into an interim list of 142 questions. Two ranking rounds (n\u00a0=\u2009242, n\u00a0=\u2009252) reduced the list to 20 questions (10 brain health, 10 dementia). Interest-holders included people living with cognitive impairment (n\u00a0=\u200948, 6\u00b78%), current or previous caregivers (n\u00a0=\u2009217, 30\u00b77%), public contributors (n\u00a0=\u2009261, 37\u00b70%), and professionals (n\u00a0=\u2009134, 19\u00b70%). Risk reduction was a leading brain health priority, while early diagnosis was a top dementia priority. Research around brain resilience and improving dementia care pathways was selected as having greatest potential impact.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We established Scotland-specific research priorities for brain health and dementia, which we advocate to researchers, funders and decision-makers. Our national research prioritisation exercise received engagement from diverse interest-holders, ensuring a range of voices will inform future research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ageing\/afag261","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:03:21Z","timestamp":1792454601000},"source":"Crossref","is-referenced-by-count":0,"title":["Scottish priorities for dementia and brain health research\u2014results of a national research priority setting exercise"],"prefix":"10.1093","volume":"55","author":[{"given":"Fenna Maria Alexandra","family":"Lunter","sequence":"first","affiliation":[{"name":"School of Cardiovascular and Metabolic Health, University of Glasgow , Glasgow, Scotland ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winnie","family":"Henry","sequence":"additional","affiliation":[{"name":"Public Contributor, NHS Research Scotland Neuroprogressive and Dementia Network , Edinburgh ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ross","sequence":"additional","affiliation":[{"name":"Public Contributor, NHS Research Scotland Neuroprogressive and Dementia Network , Edinburgh ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqui","family":"Kerr","sequence":"additional","affiliation":[{"name":"NHS Research Scotland Neuroprogressive and Dementia Network , Edinburgh ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Law","sequence":"additional","affiliation":[{"name":"NHS Research Scotland Neuroprogressive and Dementia Network , Edinburgh ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8701-9043","authenticated-orcid":false,"given":"Stephen","family":"Makin","sequence":"additional","affiliation":[{"name":"School of Medicine , Medical Sciences and Nutrition (Centre for Rural Health), , Aberdeen, Scotland ,","place":["UK"]},{"name":"University of Aberdeen , Medical Sciences and Nutrition (Centre for Rural Health), , Aberdeen, Scotland ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Mckean","sequence":"additional","affiliation":[{"name":"Brain Health Scotland, Alzheimer Scotland , Edinburgh ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom C","family":"Russ","sequence":"additional","affiliation":[{"name":"NHS Research Scotland Neuroprogressive and Dementia Network , Edinburgh ,","place":["UK"]},{"name":"Ageing and Health, Usher Institute , Edinburgh ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5678-4583","authenticated-orcid":false,"given":"Lucy","family":"Stirland","sequence":"additional","affiliation":[{"name":"Division of Psychiatry, The University of Edinburgh Centre for Clinical Brain Sciences, Kennedy Tower Royal Edinburgh Hospital , Morningside Terrace, Edinburgh EH10 5HF ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7375-4776","authenticated-orcid":false,"given":"Susan Deborah","family":"Shenkin","sequence":"additional","affiliation":[{"name":"Ageing and Health, The University of Edinburgh Usher Institute of Population Health Sciences and Informatics , 9 Little France Road, Edinburgh EH16 4UX ,","place":["UK"]},{"name":"Advanced Care Research Centre, The University of Edinburgh Usher Institute of Population Health Sciences and Informatics , Edinburgh ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4752-6988","authenticated-orcid":false,"given":"Jennifer Kirsty","family":"Burton","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Metabolic Health, University of Glasgow , Glasgow, Scotland ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1401-0181","authenticated-orcid":false,"given":"Terence J","family":"Quinn","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Metabolic Health, University of Glasgow , Glasgow, Scotland ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,20]]},"reference":[{"key":"2026101920031396900_ref1","volume-title":"World Alzheimer Report 2015. 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