{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:46:24Z","timestamp":1792255584795,"version":"4.4.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T00:00:00Z","timestamp":1785715200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Hospitalised older adults are at increased risk of hospitalisation-associated disability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>to investigate the effects of an in-hospital exercise program on functional and cognitive outcomes in older adults admitted to an Acute Care for the Elderly (ACE) unit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This randomised controlled trial included acutely hospitalised older adults (\u226570\u00a0years) randomised to an exercise intervention based on VIVIFRAIL program [intervention group (IG)] or usual care [control group (CG)]. Exercise intervention included resistance\/power training, balance and gait exercises. Primary outcome was the Short Physical Performance Battery (SPPB). Secondary outcomes included handgrip strength, gait speed, balance, timed-up-and-go, sit-to-stand (STS) time and relative STS power, global cognitive function using Mini Mental State Examination (MMSE), executive function and depressive symptoms. Assessments were performed at ACE unit admission and discharge. Analyses followed the intention-to-treat principle using generalised estimating equations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty-seven participants (83.1\u2009\u00b1\u20095.1\u00a0years, 33% women) were randomised into the groups and performed 4\u2009\u00b1\u20092 exercise sessions across the hospitalisation period. Significant time \u00d7 group interactions were found for SPPB, STS time, maximal and mean relative STS power, balance and MMSE, favouring IG compared to CG. Between-groups mean differences at discharge were observed for SPPB [3.18 points, 95% CI (1.3, 5.1)], STS time [\u221211.3\u00a0s, (\u221220.6, \u22121.9)], maximal relative STS power [1.45\u00a0W\/Kg, (0.3, 2.5)], mean relative STS power [0.70\u00a0W\/Kg, (0.2, 1.2)] and MMSE [2.16 points, (0.6, 3.7)] favouring IG compared to CG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Multicomponent exercise may attenuate physical and cognitive declines during acute hospitalisation. These findings support the implementation of structured exercise programmes during hospitalisation. (Registration number: NCT06682598).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ageing\/afag301","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:27:07Z","timestamp":1791199627000},"source":"Crossref","is-referenced-by-count":0,"title":["Preservation of functional capacity and lower-limb mechanical power during acute hospitalisation: effects of a low-cost multicomponent exercise programme in older adults\u2014a randomised controlled trial"],"prefix":"10.1093","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5649-552X","authenticated-orcid":false,"given":"Marcelo","family":"Bandeira-Guimar\u00e3es","sequence":"first","affiliation":[{"name":"School of Physical Education, Physiotherapy and Dance, Universidade Federal do Rio Grande do Sul , Rua Felizardo, 750 ESEFID, Porto Alegre, RS 90690-200 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Vieillissement, Centre Hospitalo-Universitaire de Toulouse , Toulouse, Occitanie,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato G B","family":"de Mello","sequence":"additional","affiliation":[{"name":"School of Medicine, Universidade Federal do Rio Grande do Sul , Porto Alegre, RS ,","place":["Brazil"]},{"name":"Department of Internal Medicine, Hospital de Clinicas de Porto Alegre , Porto Alegre, RS ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martim","family":"Bottaro","sequence":"additional","affiliation":[{"name":"College of Physical Education, Strength and Conditioning Research Laboratory, Universidade de Bras\u00edlia , Bras\u00edlia, DF ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio H","family":"Moriguchi","sequence":"additional","affiliation":[{"name":"School of Medicine, Universidade Federal do Rio Grande do Sul , Porto Alegre, RS 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