{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T16:42:23Z","timestamp":1792773743015,"version":"4.5.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000},"content-version":"vor","delay-in-days":81,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fall-risk-increasing drugs (FRIDs) may contribute to a higher falls-risk in older people, but research examining standardised screening tools is limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To examine FRID prevalence in community-dwelling older adults, any association with subsequent fall-related hospital admissions, and FRID prescriptions before and after admission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects\/setting<\/jats:title>\n                    <jats:p>Adults aged \u226565\u00a0years across 44 general practices in Ireland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Fourteen FRIDs, defined by Screening Tool of Older Persons Prescriptions in older adults with high Fall risk (STOPPFall) criteria, were examined as time-varying exposures from 2012 to 2016. The association between FRID exposure and fall-related admissions was estimated using Cox proportional hazards models, adjusted for relevant confounders. Participants\u2019 FRID use pre- and post-fall-related admission was analysed descriptively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>Of the 35 942 participants, 16 780 (47%) were prescribed at least one long-term FRID at baseline, and 867 (2.4%) experienced a subsequent fall-related admission. Long-term FRID use was associated with a higher risk of fall-related admission [adjusted hazard ratio (aHR) 2.85, 95% CI 2.13\u20133.82, P\u00a0&amp;lt;\u2009.001], demonstrating a stronger association with an increasing FRID burden\u2014one FRID: aHR 2.81 (95% CI 2.07\u20133.82, P\u00a0&amp;lt;\u2009.001); \u22655 FRIDs: 5.67 (95% CI 3.70\u20138.70, P\u00a0&amp;lt;\u2009.001). Long-term FRID prevalence measured pre- and post-fall-related admission was unchanged (53.9%\u201353.2%). A total of 148 (19.5%) participants had a FRID discontinued, 86 (11.3%) were prescribed an additional FRID and 110 (14.5%) had a FRID initiated for the first time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>FRID use, defined via STOPPFall, was prevalent in older adults and associated with a substantially increased risk of injurious falls. FRID use remained unchanged following discharge. Guidelines recommend including medication review in fall-risk assessments, but further work is needed to embed this across health systems.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ageing\/afag303","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T16:05:17Z","timestamp":1792771517000},"source":"Crossref","is-referenced-by-count":0,"title":["Fall-risk-increasing drug use in older community-dwelling adults: prevalence, association with fall-related admissions and post-discharge prescribing changes\u2014a retrospective cohort study"],"prefix":"10.1093","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5823-9614","authenticated-orcid":false,"given":"Steven","family":"Gilmore","sequence":"first","affiliation":[{"name":"Department of General Practice, School of Medicine, University College Cork , Cork 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Population Health, RCSI University of Medicine and Health Sciences , Dublin ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2986-5994","authenticated-orcid":false,"given":"Caroline","family":"McCarthy","sequence":"additional","affiliation":[{"name":"Department of General Practice, RCSI University of Medicine and Health Sciences , Dublin ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9369-749X","authenticated-orcid":false,"given":"Ryan","family":"Muddiman","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences , Dublin 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