{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T04:10:06Z","timestamp":1751256606988,"version":"3.41.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1962,9,1]],"date-time":"1962-09-01T00:00:00Z","timestamp":-231465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[1962,9]]},"DOI":"10.1093\/ajcn\/11.3.180","type":"journal-article","created":{"date-parts":[[2018,1,30]],"date-time":"2018-01-30T07:50:11Z","timestamp":1517298611000},"page":"180-186","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"title":["Factors Affecting Human Antibody Response"],"prefix":"10.1016","volume":"11","author":[{"given":"ROBERT E.","family":"HODGES","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"WILLIAM B.","family":"BEAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARGARET A.","family":"OHLSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ROBERTA E.","family":"BLEILER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/ajcn\/11.3.180_bib1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3181\/00379727-66-16010","article-title":"Circulating antibodies in vitamin deficiency states. I. Pyridoxine, riboflavin and pantothenic acid deficiencies","volume":"66","author":"AXELROD","year":"1947","journal-title":"Proc. Soc. Exper. Biol & Med."},{"key":"10.1093\/ajcn\/11.3.180_bib2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/jn\/72.3.325","article-title":"Effects of pantothenic acid, pyridoxine and thiamine deficiencies upon antibody formation to influenza virus PR-8 in rats","volume":"72","author":"AXELROD","year":"1960","journal-title":"J. Nutrition"},{"key":"10.1093\/ajcn\/11.3.180_bib3","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1001\/archinte.1958.00260130157016","article-title":"Vitamin B6 in internal medicine","volume":"101","author":"WAYNE","year":"1958","journal-title":"Arch. Int. Med."},{"key":"10.1093\/ajcn\/11.3.180_bib4","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/ajcn\/11.2.85","article-title":"Factors affecting human antibody response, \u026a\u026a\u026a. Immunologic responses of men deficient in pantothenic acid","volume":"11","author":"HODGES","year":"1962","journal-title":"Am. J. Clin. Nutrition"},{"key":"10.1093\/ajcn\/11.3.180_bib5","doi-asserted-by":"crossref","first-page":"580","DOI":"10.3181\/00379727-76-18565","article-title":"Plasma cholesterol levels of cholesterol fed control and deficient monkeys","volume":"76","author":"GREENBERG","year":"1951","journal-title":"Proc. Soc. Exper. Biol. & Med."},{"key":"10.1093\/ajcn\/11.3.180_bib6","first-page":"121","article-title":"Seborrheic dermatitis. A local metabolic defect involving pyridoxine","volume":"40","author":"SCHREINER","year":"1952","journal-title":"J. Lab. & Clin. Med."},{"key":"10.1093\/ajcn\/11.3.180_bib7","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0021-9258(19)52742-9","article-title":"Studieson free erythrocyte protoporphyrin, plasma copper and plasma iron in normal and pyridoxine- deficient swine","volume":"172","author":"CARTWRIGHT","year":"1948","journal-title":"J. Biol. Chem."},{"key":"10.1093\/ajcn\/11.3.180_bib8","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3181\/00379727-91-22284","article-title":"Pyridoxine responsive anemia in the human adult","volume":"91","author":"HARRIS","year":"1956","journal-title":"Proc. Soc. Exper. Biol. & Med."},{"key":"10.1093\/ajcn\/11.3.180_bib9","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1093\/ajcn\/1.3.200","article-title":"Pyridoxine deficiency in the human infant","volume":"1","author":"SNYDERMAN","year":"1953","journal-title":"Am. J. Clin. Nutrition"},{"key":"10.1093\/ajcn\/11.3.180_bib10","doi-asserted-by":"crossref","first-page":"312","DOI":"10.3181\/00379727-77-18762","article-title":"Relationship of pyridoxine deficiency to adrenal function in production of leucocytes in man","volume":"77","author":"MUELLER","year":"1951","journal-title":"Proc. Soc. Exper. Biol. & Med."},{"key":"10.1093\/ajcn\/11.3.180_bib11","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1172\/JCI103756","article-title":"Pantothenic acid deficiency in man","volume":"37","author":"HODGES","year":"1958","journal-title":"J. Clin. Invest."},{"key":"10.1093\/ajcn\/11.3.180_bib12","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1001\/jama.1954.02940390030009","article-title":"Convulsive seizures in infants with pyridoxine-deficient diet","volume":"154","author":"COURSIN","year":"1954","journal-title":"J.A.M.A."},{"key":"10.1093\/ajcn\/11.3.180_bib13","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/S0022-3565(25)25762-7","article-title":"Xanthurenic acid excretion and possible pyridoxine deficiency produced by isonicotinic acid hydrazide and other convulsant hydrazides","volume":"128","author":"WILLIAMS","year":"1960","journal-title":"J. Pharmacol. & Exper. Therap."},{"key":"10.1093\/ajcn\/11.3.180_bib14","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3181\/00379727-82-20100","article-title":"Effect of vitamin B\u00ab deficiency on hepatic transaminase and cysteine desulfhydrase systems","volume":"82","author":"MEISTER","year":"1953","journal-title":"Proc. Soc. Exper. Biol. & Med."},{"key":"10.1093\/ajcn\/11.3.180_bib15","doi-asserted-by":"crossref","first-page":"555","DOI":"10.3181\/00379727-84-20709","article-title":"Antagonist studies. Comparison of desoxypyridoxine and pyridoxine deficiency therapy on various vitamin Be enzymes","volume":"84","author":"DIETRICH","year":"1953","journal-title":"Proc. Soc. Exper. Biol. & Med."},{"key":"10.1093\/ajcn\/11.3.180_bib16","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1093\/jn\/71.4.416","article-title":"The relative effects of pyridoxine deficiency on two plasma transaminases in the growing and in the adult rat","volume":"71","author":"BRIN","year":"1960","journal-title":"J. Nutrition"},{"key":"10.1093\/ajcn\/11.3.180_bib17","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1172\/JCI103559","article-title":"Quantitative studies on human urinary metabolites of tryptophan as affected by isoniazide and desoxypyridoxine","volume":"36","author":"PRICE","year":"1957","journal-title":"J. Clin. Invest."}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523345933?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523345933?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/11\/3\/180\/23692002\/180.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T03:56:36Z","timestamp":1751255796000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523345933"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1962,9]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1962,9]]}},"alternative-id":["S0002916523345933"],"URL":"https:\/\/doi.org\/10.1093\/ajcn\/11.3.180","relation":{},"ISSN":["0002-9165"],"issn-type":[{"type":"print","value":"0002-9165"}],"subject":[],"published":{"date-parts":[[1962,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Factors Affecting Human Antibody Response","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ajcn\/11.3.180","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1962 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}