{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T16:10:50Z","timestamp":1757779850417},"reference-count":20,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[1966,12,1]],"date-time":"1966-12-01T00:00:00Z","timestamp":-97372800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[1966,12]]},"DOI":"10.1093\/ajcn\/19.5.379","type":"journal-article","created":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T03:44:24Z","timestamp":1517197464000},"page":"379-383","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Pyridoxine Deficiency and Tryptophan Metabolism in Chronic Alcoholics"],"prefix":"10.1016","volume":"19","author":[{"given":"M.P.","family":"WALSH","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.J.N.","family":"HOWORTH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"VINCENT","family":"MARKS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/ajcn\/19.5.379_bib1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/ajcn\/15.2.59","article-title":"Vitamin B6 requirement for adult men.","volume":"15","author":"BAKER","year":"1964","journal-title":"Am. J. Clin. Nutrition"},{"key":"10.1093\/ajcn\/19.5.379_bib2","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/ajcn\/14.1.56","article-title":"Recommendations for standardization of tryptophan load test.","volume":"14","author":"COURSIN","year":"1964","journal-title":"Am. J. Clin. Nutrition"},{"key":"10.1093\/ajcn\/19.5.379_bib3","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/bmj.1.5379.327","article-title":"Disorders of amino-acid transport.","volume":"1","author":"MILNE","year":"1964","journal-title":"Brit. M. J."},{"key":"10.1093\/ajcn\/19.5.379_bib4","doi-asserted-by":"crossref","first-page":"841","DOI":"10.3181\/00379727-98-24203","article-title":"Association of pyridoxine deficiency and convulsions in alcoholics.","volume":"98","author":"LERNER","year":"1958","journal-title":"Proc. Soc. Exper. Biol. & Med."},{"key":"10.1093\/ajcn\/19.5.379_bib5","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1056\/NEJM196012082632304","article-title":"Evidence for a defect in tryptophan metabolism in chronic alcoholism.","volume":"263","author":"OLSEN","year":"1960","journal-title":"New England J. Med."},{"key":"10.1093\/ajcn\/19.5.379_bib6","first-page":"565","article-title":"Urinary excretion of 5-H.I.A.A. in chronic alcoholism.","volume":"182","author":"MURPHY","year":"1962","journal-title":"J. A. M. A."},{"key":"10.1093\/ajcn\/19.5.379_bib7","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1136\/bmj.2.5420.1290","article-title":"Peripheral neuropathy of the alcoholic. I. Aetiological role of aneurin and other B-complex vitamins.","volume":"2","author":"FENNELLY","year":"1964","journal-title":"Brit. M. J."},{"key":"10.1093\/ajcn\/19.5.379_bib8","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0009-8981(65)90072-0","article-title":"Separation and estimation of tryptophan-nicotinic acid metabolites in urine by thin-layer chromatography.","volume":"11","author":"WALSH","year":"1965","journal-title":"Clin. chim. acta"},{"key":"10.1093\/ajcn\/19.5.379_bib9","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0021-9258(19)81408-4","article-title":"The identification of 5-hydroxy-3-indoleacetic acid in normal urine and a method for its assay.","volume":"216","author":"UDENFRIEND","year":"1955","journal-title":"J. Biol. Chem."},{"key":"10.1093\/ajcn\/19.5.379_bib10","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1093\/ajcp\/46.2_ts.282","article-title":"Determination of plasma pyridoxal phosphate using wheat germ glutamic-aspartic apotransaminase.","volume":"36","author":"WALSH","year":"1966","journal-title":"Am. J. Clin. Path."},{"key":"10.1093\/ajcn\/19.5.379_bib11","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1136\/bmj.1.4816.935-c","article-title":"Letter to Editor. Intravenous detoxication of alcohol.","volume":"1","author":"WORDSWORTH","year":"1953","journal-title":"Brit. M. J."},{"key":"10.1093\/ajcn\/19.5.379_bib12","first-page":"12","article-title":"The effect of pyridoxine hydrochloride in acute alcoholic intoxication.","volume":"46","author":"SMALL","year":"1955","journal-title":"J. Lab. & Clin. Med."},{"key":"10.1093\/ajcn\/19.5.379_bib13","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1042\/bj0610328","article-title":"The relation between thiamine, biotin and tryptophan metabolism, studied in the rat.","volume":"61","author":"DALGLIESH","year":"1955","journal-title":"Biochem. J."},{"key":"10.1093\/ajcn\/19.5.379_bib14","first-page":"65","article-title":"Studio sul metabolismo triptofano.","volume":"12","author":"QUAGLIARIELLO","year":"1963","journal-title":"Gior. biochim."},{"key":"10.1093\/ajcn\/19.5.379_bib15","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1093\/ajcn\/11.5.502","article-title":"Tryptophan and nicotinic acid metabolism in patients with cirrhosis of the liver.","volume":"11","author":"GABUZDA","year":"1962","journal-title":"Am. J. Clin. Nutrition"},{"key":"10.1093\/ajcn\/19.5.379_bib16","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/S0021-9258(18)57289-6","article-title":"The effect of pyridoxine deficiency on the tryptophan niacin transformation in rats.","volume":"174","author":"LING","year":"1948","journal-title":"J. Biol. Chem."},{"key":"10.1093\/ajcn\/19.5.379_bib17","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S0021-9258(18)56203-7","article-title":"Relation of tryptophan and niacin to pyridine nucleotides of tissue.","volume":"187","author":"WILLIAMS","year":"1950","journal-title":"J. Biol. Chem."},{"key":"10.1093\/ajcn\/19.5.379_bib18","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1056\/NEJM196402202700806","article-title":"Metabolic effects of alcohol on the liver.","volume":"270","author":"ISSELBACHER","year":"1964","journal-title":"New England J. Med."},{"key":"10.1093\/ajcn\/19.5.379_bib19","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/S0026-0495(65)80005-1","article-title":"Effects of experimentally induced intoxication on metabolism of ethanol-1-C14 in alcoholic subjects.","volume":"14","author":"MENDELSON","year":"1965","journal-title":"Metabolism"},{"key":"10.1093\/ajcn\/19.5.379_bib20","first-page":"101","article-title":"Pyridine nucleotides in the prevention, diagnosis and treatment of problem drinkers.","volume":"69","author":"O\u2019HOLLAREN","year":"1961","journal-title":"West. J. Surg."}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523308335?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523308335?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/19\/6\/379\/25412456\/379.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T13:25:45Z","timestamp":1698758745000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523308335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1966,12]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1966,12]]}},"alternative-id":["S0002916523308335"],"URL":"https:\/\/doi.org\/10.1093\/ajcn\/19.5.379","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[1966,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pyridoxine Deficiency and Tryptophan Metabolism in Chronic Alcoholics","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ajcn\/19.5.379","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1966 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}