{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T13:05:56Z","timestamp":1762607156360},"reference-count":27,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[1968,8,1]],"date-time":"1968-08-01T00:00:00Z","timestamp":-44755200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[1968,8]]},"DOI":"10.1093\/ajcn\/21.8.820","type":"journal-article","created":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T03:43:36Z","timestamp":1517197416000},"page":"820-826","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"title":["Experimental Protein-Calorie Malnutrition"],"prefix":"10.1016","volume":"21","author":[{"given":"R.E.","family":"KIRSCH","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.F.","family":"BROCK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.J.","family":"SAUNDERS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/ajcn\/21.8.820_bib1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0022-3476(59)80067-6","article-title":"Review of current knowledge concerning kwashiorkor.","volume":"54","author":"JELLIFFE","year":"1959","journal-title":"J. Pediat."},{"key":"10.1093\/ajcn\/21.8.820_bib2","doi-asserted-by":"crossref","first-page":"877","DOI":"10.7326\/0003-4819-65-5-877","article-title":"Dietary protein deficiency.","volume":"65","author":"BROCK","year":"1966","journal-title":"Ann. Internal Med."},{"key":"10.1093\/ajcn\/21.8.820_bib3","unstructured":"BROCK, J. F., AND A. S. TRUSWELL. In press."},{"key":"10.1093\/ajcn\/21.8.820_bib4","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.1.4928.1439","article-title":"Effects of dietary protein, lipotropic factors and realimentation on total hepatic lipids and their distribution.","author":"BEST","year":"1955","journal-title":"Brit. Med. J."},{"key":"10.1093\/ajcn\/21.8.820_bib5","doi-asserted-by":"crossref","first-page":"523","DOI":"10.3181\/00379727-96-23527","article-title":"Kwashiorkor-like syndrome observed in monkeys fed maize.","volume":"96","author":"FOLLIS","year":"1957","journal-title":"Proc. Soc. Exptl. Biol. Med."},{"key":"10.1093\/ajcn\/21.8.820_bib6","first-page":"119","article-title":"Chemical pathology of acute amino acid deficiencies. 1. Morphologic changes in immature rats fed threonine, or methionine or histidine-devoid diets.","volume":"66","author":"SIDRANSKY","year":"1958","journal-title":"A.M.A. Arch. Pathol."},{"key":"10.1093\/ajcn\/21.8.820_bib7","first-page":"14","article-title":"Experimental protein deficiency.","volume":"80","author":"DEO","year":"1965","journal-title":"AM.A. Arch. Pathol."},{"key":"10.1093\/ajcn\/21.8.820_bib8","first-page":"445","article-title":"Experimental protein-calorie deficiency","volume":"2","author":"PLATT","year":"1964"},{"key":"10.1093\/ajcn\/21.8.820_bib9","first-page":"6","article-title":"Pathology of acute experimental protein malnutrition in the force-fed rat.","volume":"21","author":"PLATT","year":"1962","journal-title":"Proc. Nutr. Soc. Engl. Scot."},{"key":"10.1093\/ajcn\/21.8.820_bib10","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1079\/BJN19570036","article-title":"Effect of a low protein diet on the chemical composition of the bodies and tissues of young rats.","volume":"11","author":"WIDDOWSON","year":"1957","journal-title":"Brit. J. Nutr."},{"key":"10.1093\/ajcn\/21.8.820_bib11","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0140-6736(54)91502-0","article-title":"Kwashiorkor.","volume":"1","author":"BROCK","year":"1954","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/21.8.820_bib12","first-page":"273","article-title":"Studies in serum proteins. 5. A rapid procedure for the estimation of total protein, true albumin, total globulin, alpha globulin, beta globulin and gamma globulin in 1.0 ml. of serum.","volume":"18","author":"WOLFSON","year":"1948","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1093\/ajcn\/21.8.820_bib13","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1021\/ac60206a024","article-title":"Ion exchange chromatography of amino acids.","volume":"35","author":"HAMILTON","year":"1963","journal-title":"Anal. Chem."},{"key":"10.1093\/ajcn\/21.8.820_bib14","first-page":"637","article-title":"Proc. Technicon Symp. Automation Anal. Chem.","author":"EFRON","year":"1966","journal-title":"Proc. Technicon Symp. Automation Anal. Chem."},{"key":"10.1093\/ajcn\/21.8.820_bib15","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1038\/201546a0","article-title":"Perspectives in protein malnutrition.","volume":"201","author":"RAMALINGASWAMI","year":"1964","journal-title":"Nature"},{"key":"10.1093\/ajcn\/21.8.820_bib16","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/S0140-6736(66)92439-1","article-title":"Protein deficiencies and calorie deficiencies.","volume":"2","author":"MCCANCE","year":"1966","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/21.8.820_bib17","first-page":"523","article-title":"Clinical aspects of protein malnutrition","volume":"2","author":"VITERI","year":"1964"},{"key":"10.1093\/ajcn\/21.8.820_bib18","series-title":"Kwashiorkor.","article-title":"Kwashiorkor.","author":"TROWELL","year":"1954"},{"key":"10.1093\/ajcn\/21.8.820_bib19","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1749-6632.1961.tb35544.x","article-title":"The effects of protein depletion and repletion on the concentration and distribution of serum proteins and protein bound carbohydrates of the adult rat.","volume":"94","author":"WIEMER","year":"1961","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1093\/ajcn\/21.8.820_bib20","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1079\/BJN19610028","article-title":"The effect of dietary protein deficiency on transport of vitamin A in the blood and its storage in the liver.","volume":"15","author":"FRIEND","year":"1961","journal-title":"Brit. J. Nutr."},{"key":"10.1093\/ajcn\/21.8.820_bib21","first-page":"23","article-title":"The biochemical assessment of protein nutritional status. 1. Marginal hypoalbuminaemia. 2. Serum cholinesterase.","volume":"8","author":"SCHENDEL","year":"1962","journal-title":"S. African J. Lab. Clin. Med."},{"key":"10.1093\/ajcn\/21.8.820_bib22","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1136\/adc.33.172.499","article-title":"The plasma amino acids in malnutrition.","volume":"33","author":"WESTALL","year":"1958","journal-title":"Arch. Disease Childhood"},{"key":"10.1093\/ajcn\/21.8.820_bib23","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/S0140-6736(63)90734-7","article-title":"The plasma aminogram in kwashiorkor.","volume":"2","author":"HOLT","year":"1963","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/21.8.820_bib24","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1093\/ajcn\/11.5.517","article-title":"The free amino acids in blood plasma of children with kwashiorkor and marasmus.","volume":"11","author":"ARROYAVE","year":"1962","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1093\/ajcn\/21.8.820_bib25","unstructured":"Vis, H. Aspects et mechanismes des hyperaminoaciduries de l\u2019enfance, Brussels: Editions Arscia, 1964."},{"key":"10.1093\/ajcn\/21.8.820_bib26","first-page":"1","article-title":"Protein and amino acid metabolism in kwashiorkor.","volume":"29","author":"EDOZIEN","year":"1965","journal-title":"Clin. Sci."},{"key":"10.1093\/ajcn\/21.8.820_bib27","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0140-6736(67)92233-7","article-title":"Plasma free amino acids in protein calorie malnutrition. Reappraisal of its diagnostic value.","volume":"2","author":"SAUNDERS","year":"1967","journal-title":"Lancet"}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523321178?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523321178?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/21\/8\/820\/24192371\/820.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T13:30:07Z","timestamp":1698759007000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523321178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1968,8]]},"references-count":27,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1968,8]]}},"alternative-id":["S0002916523321178"],"URL":"https:\/\/doi.org\/10.1093\/ajcn\/21.8.820","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[1968,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Experimental Protein-Calorie Malnutrition","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ajcn\/21.8.820","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1968 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}