{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T18:24:34Z","timestamp":1782757474084,"version":"3.54.5"},"reference-count":17,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1969,5,1]],"date-time":"1969-05-01T00:00:00Z","timestamp":-21168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1969,5,1]],"date-time":"1969-05-01T00:00:00Z","timestamp":-21168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The American Journal of Clinical Nutrition"],"published-print":{"date-parts":[[1969,5]]},"DOI":"10.1093\/ajcn\/22.5.535","type":"journal-article","created":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T09:12:30Z","timestamp":1516698750000},"page":"535-548","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":188,"title":["Experimental Scurvy in Man"],"prefix":"10.1016","volume":"22","author":[{"given":"ROBERT E.","family":"HODGES","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EUGENE M.","family":"BAKER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JAMES","family":"HOOD","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HOWERDE E.","family":"SAUBERLICH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"STEVEN C.","family":"MARCH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/ajcn\/22.5.535_bib1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1753-4887.1968.tb00850.x","article-title":"Present knowledge of ascorbic acid.","volume":"26","author":"KING","year":"1968","journal-title":"Nutr. Rev."},{"key":"10.1093\/ajcn\/22.5.535_bib2","unstructured":"Recommended Dietary allowances. Natl. Acad. Sci-Natl. Res. Council Publ. 1146. (6th rev. ed.) 1964, p. 23-24."},{"key":"10.1093\/ajcn\/22.5.535_bib3","year":"1950"},{"key":"10.1093\/ajcn\/22.5.535_bib4","series-title":"Med. Res. Council Special Rept. Ser.","article-title":"Med. Res. Council Special Rept. Ser.","author":"BARTLEY","year":"1953"},{"key":"10.1093\/ajcn\/22.5.535_bib5","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1001\/jama.1967.03130190119018","article-title":"The use of prisoners for medical research.","volume":"202","author":"HODGES","year":"1967","journal-title":"J. Am. Med. Assoc."},{"key":"10.1093\/ajcn\/22.5.535_bib6","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/ajcn\/22.5.549","article-title":"Metabolism of ascorbic-1-14C acid in experimental human scurvy.","volume":"22","author":"BAKER","year":"1969","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1093\/ajcn\/22.5.535_bib7","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/ajcn\/11.2.85","article-title":"Factors affecting human antibody response. III. Immunologic responses of men deficient in pantothenic acid.","volume":"11","author":"HODGES","year":"1962","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1093\/ajcn\/22.5.535_bib8","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1093\/ajcn\/22.5.559","article-title":"Ocular lesions in scurvy.","volume":"22","author":"HOOD","year":"1969","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1093\/ajcn\/22.5.535_bib9","unstructured":"BURKLEY, K. Urinary hydroxyproline excretion in scurvy (Master\u2019s Thesis). Iowa City: University of Iowa, 1968."},{"key":"10.1093\/ajcn\/22.5.535_bib10","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S0140-6736(00)94709-3","article-title":"William Stark, M.D., an eighteenth century experiment in nutrition.","volume":"2","author":"DRUMMOND","year":"1935","journal-title":"Lancet"},{"key":"10.1093\/ajcn\/22.5.535_bib11","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1056\/NEJM194009052231001","article-title":"Experimental human scurvy.","volume":"223","author":"CRANDON","year":"1940","journal-title":"New Engl. J. Med."},{"key":"10.1093\/ajcn\/22.5.535_bib12","first-page":"303","article-title":"Vitamin C economy in the human subject.","volume":"75","author":"PIJOAN","year":"1944","journal-title":"Bull. Johns Hopkins Hosp."},{"key":"10.1093\/ajcn\/22.5.535_bib13","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1042\/bj0302291","article-title":"On the amount of ascorbic acid in blood and urine. The daily human requirements for ascorbic acid.","volume":"30","author":"VAN EEKELEN","year":"1936","journal-title":"Biochem. J."},{"key":"10.1093\/ajcn\/22.5.535_bib14","first-page":"1","article-title":"\u00dcber experimentelle. Skorbut. Ein Beitrag zur Lehre von dem Einfluss einer einseitigen Nahrung. Z.","volume":"72","author":"HOLST","year":"1912","journal-title":"Hyg. Infektionskrankh."},{"key":"10.1093\/ajcn\/22.5.535_bib15","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1136\/bmj.2.4632.863","article-title":"The Falkland Islands Dependencies Survey.","volume":"2","author":"ROBERTS","year":"1949","journal-title":"Brit. Med. J."},{"key":"10.1093\/ajcn\/22.5.535_bib16","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/j.1749-6632.1961.tb46123.x","article-title":"Human requirements for vitamin C and its use in clinical medicine.","volume":"92","author":"GOLDSMITH","year":"1961","journal-title":"Ann. N.Y. Acad. Sei."},{"key":"10.1093\/ajcn\/22.5.535_bib17","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1038\/1911008b0","article-title":"Influence of scurvy and lathyrism (odoratism) on hydroxyproline excretion.","volume":"191","author":"MARTIN","year":"1961","journal-title":"Nature"}],"container-title":["The American Journal of Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523323013?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002916523323013?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ajcn\/article-pdf\/22\/5\/535\/24158489\/535.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T19:43:03Z","timestamp":1733946183000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002916523323013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,5]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1969,5]]}},"alternative-id":["S0002916523323013"],"URL":"https:\/\/doi.org\/10.1093\/ajcn\/22.5.535","relation":{},"ISSN":["0002-9165"],"issn-type":[{"value":"0002-9165","type":"print"}],"subject":[],"published":{"date-parts":[[1969,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Experimental Scurvy in Man","name":"articletitle","label":"Article Title"},{"value":"The American Journal of Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/ajcn\/22.5.535","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1969 American Society for Nutrition. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}